Exam 1 Flashcards

1
Q

What Disorder do these drugs Tx?
Are these Drugs 1st or 2nd Generation?
Do they treat + or - S&S?

Haloperidol (Haldol)

Chlorpromazine (Thorazine)
Thioridazine (Mellaril)
Perphenazine (Trilafon)
Trifluoeerazine (Stelazine)
Fluphenazine (Prolixin)

Loxapine (Loxitane)
Molindone (Moban)

A
  • Schizophrenia
  • 1st Generation
  • Treat + S&S
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2
Q

What Disorder do these drugs Tx?
Are these Drugs 1st or 2nd Generation?
Do they treat + or - S&S?

Aripiprazole (Abilify)

Clozapine (Clozaril)
Quetiapine (Seroquel)
Olanzapine (Zyprexa)
Asenapine (Saphris)

Risperidone (Risperdel)
Paliperidone (Invega)
Ziprasidone (Geodon)
Iloperidone (Fanapt)
Lurasidone (Latuda)
A
  • Schizophrenia
  • 2nd Generation
  • Both + & - S&S
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3
Q

Which Generation of drugs for Schizophrenia cause MORE Extrapyramidal Side Effects (EPS)?

What are those Symptoms?

A

-1st Generation

  • Pseudoparkinsonism
  • Acute Dystonic Reactions
  • Akathisia
  • Tardive Dyskenesia
  • Anticholenergic (↑ in 1st gen but also in 2nd gen)
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4
Q

What is Pseudoparkinsonism?

What is used to Treat it?

A

-S&S of 1st gen drugs that Mimic Parkinsons; Mask like face, Shuffling gate, Stiff/Stooped Posture, Drooling, Tremor, Pill Rolling.

  • Artane,
  • Benztropine (Cogentin)
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5
Q

What is an acute Dystonic Reaction?

What is used to treat it?

A
  • S&S of 1st gen drugs; Contraction of tongue/jaw, face, neck, back.
  • 2 types: Opisthotonos, Oculogyric Crisis

-Drugs: Benadryl, Benztropine (Cogentin)

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6
Q

What is Akathisia?

What is used to treat?

A
  • S&S of 1st gen Drugs; Incessant fidgeting/rocking

- Drugs: Propranolol (Inderal), Lorazepam (Ativan), Diazapam (Valium)

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7
Q

What is Tardive Dyskinesia?

What is used to treat?

A
  • S&S of 1st gen drugs; excessive Facial fidgeting r/t mouth/tongue; Choreic movements in limbs (Rapid irregular movements/Jerky), Athetoid Limb movements (Slow Serpentine like movements), Pelvic Thrusts
  • No Known Treatment; Screening Q3mths (AIM Scale)
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8
Q

What is Neuroleptic Malignant Syndrome?

What is used to Treat it?

A

-SE of 1st gen Drugs; Increased autonomic System S&S: Increase RR, HR, Temp, HTN, Diaphoresis (Sweating), Rigidity

-Bromocriptine (Parlodel) Used 1st
Dantrolene (Dantrium) Used 2nd

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9
Q

What are the Anticholergenic S&S?

A
  • “Can’t see, Can’t Pee, Can’t spit, Can’t Shit”

- Dry mouth, urinary retention, constipation, blurred vision, photo-sensitivity, dry eyes, Impotence

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10
Q

—Adjuncts to Antipsychotic Medications—
Valium, Ativan, Xanex, and Librium are all examples of what category of drug?

______ is a Mood Stabilizer.

What other category of drug is used as an adjunct?

A
  • Benzodiazapines
  • Lithium
  • Antidepressants/SSRI’s used to treat Depression in Schizo Pt’s
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11
Q

What are the 4 A’s for Alzheimers??

A
  • Amnesia (Memory loss)
  • Aphasia (Loss of Language ability)
  • Apraxia (Loss of learned motor skills (arms in pants)
  • Agnosia (don’t recognize the familiar; senses)
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12
Q

What are these drugs used for??
Catagory and action?

Razadyne
Excelon
Aricept
Cognex (BAD S&S)

Namenda

A
  • Alzheimer’s
  • Cholinesterase Inhibitors
  • Prevent Breakdown of acetylcholine
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13
Q

What Disorder do these drugs Tx?
Are these Drugs 1st or 2nd Generation?
Haloperidol (Haldol)

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
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14
Q

Tx what?
1st or 2nd Generation?
Chlorpromazine (Thorazine)

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
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15
Q

Thioridazine (Mellaril)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
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16
Q

Perphenazine (Trilafon)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
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17
Q

Trifluoeerazine (Stelazine)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
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18
Q

Fluphenazine (Prolixin)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
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19
Q

Loxapine (Loxitane)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
20
Q

Molindone (Moban)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
21
Q

Tx what?
1st or 2nd Generation?
Aripiprazole (Abilify)

A

Schizophrenia

  • 2nd Generation
  • Both + & - S&S
22
Q

Clozapine (Clozaril)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 2nd Generation
  • Both + & - S&S
23
Q

Quetiapine (Seroquel)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 2nd Generation
  • Both + & - S&S
24
Q

Olanzapine (Zyprexa)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 2nd Generation
  • Both + & - S&S
25
Q

Asenapine (Saphris)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 2nd Generation
  • Both + & - S&S
26
Q

Risperidone (Risperdel)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 2nd Generation
  • Both + & - S&S
27
Q

Paliperidone (Invega)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 2nd Generation
  • Both + & - S&S
28
Q

Lurasidone (Latuda)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 2nd Generation
  • Both + & - S&S
29
Q

Ziprasidone (Geodon)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 2nd Generation
  • Both + & - S&S
30
Q

Iloperidone (Fanapt)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 2nd Generation
  • Both + & - S&S
31
Q
Phenobarbital (Luminal)
Class (2)
Tx What?
SE?
Nursing considerations:
A
  • anticonvulsant, barbiturate
  • generalized tonic-clonic, status epilepticus, partial, myoclonic, neonatal seizures
  • hangover, laryngospasms, angiodema, serum sickness (NOT suicidal ideation)
  • IV status epilepticus, dilute w/ NS
    PO maintenance
    1st choice for seizures in neonates
    RISK OF LONGTERM COGNITIVE DYSFUNCTION
    15-18 mg/kg IV
32
Q
Phenytoin (Dilantin)
Class (2)
Tx What?
SE?
Nursing considerations:
A
  • anti-convulsant, hydantoin
  • genralized tonic-clonic, status epilepticus, partial,
  • gingival hyperplasia, hirsutism, agranulocytosis (chk CBC) Rapid IV may cause severe hypOtension, CNS depression.
  • PO with or after food, IV undiluted 1-3 mg/kg & 50 mg/min
    INCOMPATIBLE WITH DEXTROSE! DO NOT GIVE WITH D5H20 ETC.
33
Q
Carbamazepine (Tegretol)
Class 
Tx What?
SE?
Nursing considerations:
A
  • anticonvulsant
    generalized & partial seizures
  • drowsiness, ataxia,
  • Give with food, Q6-12 months CBC & LFT
    OK for kids under 6, weight dosing. 35 mg/kg
34
Q
Gabapentin (Neurontin)
Class (2)
Tx What?
SE?
Nursing considerations:
A
  • anticonvulsant, GABA analog
  • partial & general seizures
  • drowsiness, sedation
  • don’t stop abruptly
35
Q
The following drugs are use to Tx what?
Carbamazepine (Tegretol)
Clonazepam (Klonopin)
Ethosuximide (Zarontin)
Lamotrigine (Lamictal)
Levetiracetam (Keppra)
Oxcarbazepine (Trileptal)
Phenobarbital (Luminal)
Phenytoin (Dilantin)
Topiramate (Topamax)
Valproates (Depakeane, Depakote)
A
  • seizures
36
Q

Ethosuximide (Zarontin)

Used to Tx what type of seizure?

A

Absence

give with food

37
Q

Clonazepam (Klonopin)

Used to Tx what type of seizure?

A

myoclonic, partial, atypical absence seizures

38
Q

Lamotrigine (Lamictal)

Used to Tx what type of seizure?

A

ALL types of seizures

39
Q

Levetiracetam (Keppra)

Used to Tx what type of seizure?

A

adjunct for partial
add on therapy for generalized
myoclonic epilepsy

40
Q

Oxcarbazepine (Trileptal)

Used to Tx what?

A

Epilepsy in Children 2-16

41
Q

Topiramate (Topamax)

Used to Tx what type of seizure?

A

MOST types of seizures (WTF!?!!)
(Complete BS notes - thanks again Wake Tech!)
Watch for kidney issues - care with Hx of renal calculi & Ketogenic diet

42
Q

Valproates (Depakeane, Depakote)
Used to Tx what type of seizure?
Nursing considerations?

A

Generalized & Partial
With or after food
Q6-12 months CBC LFTs
NOT for kids <2 years

43
Q
Diazepam (Valium)
Why given for seizures?
Category (3)
SE
Order of preference for admin: 1, 2, 3 routes
Nursing considerations?
A
  • Stops seizures
  • benzodiazepine, anticonvulsant, sedative
  • RESP DEPRESSION
    1. IV, 2. IM, 3. PR
  • Children give over 3-5 min. Rpt Q 15-30 min up to 10 mg. Rpt 2-4 hours
    Adults 5 mg/min q 10-15 min total 30 mg
44
Q
Why are these 3 meds given to pt. experiencing seizures?
Which one is given via IV in the ICU?
Diazepam (Valium)
Lorazepam (Ativan)
Midalozam (Versed)
A

Given to STOP seizures - follow with anti convulsant med.

- Lorazepam (Ativan)

45
Q

Lorazepam (Ativan)
Why given for seizures?
Category (3)
SE

A
  • Stops seizures
  • benzodiazepine, antianxiety, sedative
  • RESP DEPRESSION, APNEA & CARDIAC ARREST with rapid IV admin
46
Q

Which drug is preferred for status epilepticus & why?

A

Lorazepam (Ativan)

rapid onset, long 1/2 life

47
Q

Midalozam (Versed)
Why given for seizures?
Category
SE

A

Stops seizures

  • benzodiazepine,
  • RESP DEPRESSION, APNEA & CARDIAC ARREST