Exam 1 Flashcards

(47 cards)

1
Q

What Disorder do these drugs Tx?
Are these Drugs 1st or 2nd Generation?
Do they treat + or - S&S?

Haloperidol (Haldol)

Chlorpromazine (Thorazine)
Thioridazine (Mellaril)
Perphenazine (Trilafon)
Trifluoeerazine (Stelazine)
Fluphenazine (Prolixin)

Loxapine (Loxitane)
Molindone (Moban)

A
  • Schizophrenia
  • 1st Generation
  • Treat + S&S
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What Disorder do these drugs Tx?
Are these Drugs 1st or 2nd Generation?
Do they treat + or - S&S?

Aripiprazole (Abilify)

Clozapine (Clozaril)
Quetiapine (Seroquel)
Olanzapine (Zyprexa)
Asenapine (Saphris)

Risperidone (Risperdel)
Paliperidone (Invega)
Ziprasidone (Geodon)
Iloperidone (Fanapt)
Lurasidone (Latuda)
A
  • Schizophrenia
  • 2nd Generation
  • Both + & - S&S
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which Generation of drugs for Schizophrenia cause MORE Extrapyramidal Side Effects (EPS)?

What are those Symptoms?

A

-1st Generation

  • Pseudoparkinsonism
  • Acute Dystonic Reactions
  • Akathisia
  • Tardive Dyskenesia
  • Anticholenergic (↑ in 1st gen but also in 2nd gen)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is Pseudoparkinsonism?

What is used to Treat it?

A

-S&S of 1st gen drugs that Mimic Parkinsons; Mask like face, Shuffling gate, Stiff/Stooped Posture, Drooling, Tremor, Pill Rolling.

  • Artane,
  • Benztropine (Cogentin)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is an acute Dystonic Reaction?

What is used to treat it?

A
  • S&S of 1st gen drugs; Contraction of tongue/jaw, face, neck, back.
  • 2 types: Opisthotonos, Oculogyric Crisis

-Drugs: Benadryl, Benztropine (Cogentin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is Akathisia?

What is used to treat?

A
  • S&S of 1st gen Drugs; Incessant fidgeting/rocking

- Drugs: Propranolol (Inderal), Lorazepam (Ativan), Diazapam (Valium)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is Tardive Dyskinesia?

What is used to treat?

A
  • S&S of 1st gen drugs; excessive Facial fidgeting r/t mouth/tongue; Choreic movements in limbs (Rapid irregular movements/Jerky), Athetoid Limb movements (Slow Serpentine like movements), Pelvic Thrusts
  • No Known Treatment; Screening Q3mths (AIM Scale)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is Neuroleptic Malignant Syndrome?

What is used to Treat it?

A

-SE of 1st gen Drugs; Increased autonomic System S&S: Increase RR, HR, Temp, HTN, Diaphoresis (Sweating), Rigidity

-Bromocriptine (Parlodel) Used 1st
Dantrolene (Dantrium) Used 2nd

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the Anticholergenic S&S?

A
  • “Can’t see, Can’t Pee, Can’t spit, Can’t Shit”

- Dry mouth, urinary retention, constipation, blurred vision, photo-sensitivity, dry eyes, Impotence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

—Adjuncts to Antipsychotic Medications—
Valium, Ativan, Xanex, and Librium are all examples of what category of drug?

______ is a Mood Stabilizer.

What other category of drug is used as an adjunct?

A
  • Benzodiazapines
  • Lithium
  • Antidepressants/SSRI’s used to treat Depression in Schizo Pt’s
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the 4 A’s for Alzheimers??

A
  • Amnesia (Memory loss)
  • Aphasia (Loss of Language ability)
  • Apraxia (Loss of learned motor skills (arms in pants)
  • Agnosia (don’t recognize the familiar; senses)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are these drugs used for??
Catagory and action?

Razadyne
Excelon
Aricept
Cognex (BAD S&S)

Namenda

A
  • Alzheimer’s
  • Cholinesterase Inhibitors
  • Prevent Breakdown of acetylcholine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What Disorder do these drugs Tx?
Are these Drugs 1st or 2nd Generation?
Haloperidol (Haldol)

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Tx what?
1st or 2nd Generation?
Chlorpromazine (Thorazine)

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Thioridazine (Mellaril)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Perphenazine (Trilafon)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Trifluoeerazine (Stelazine)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Fluphenazine (Prolixin)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Loxapine (Loxitane)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
20
Q

Molindone (Moban)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 1st Generation
  • Treat + S&S
21
Q

Tx what?
1st or 2nd Generation?
Aripiprazole (Abilify)

A

Schizophrenia

  • 2nd Generation
  • Both + & - S&S
22
Q

Clozapine (Clozaril)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 2nd Generation
  • Both + & - S&S
23
Q

Quetiapine (Seroquel)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 2nd Generation
  • Both + & - S&S
24
Q

Olanzapine (Zyprexa)
Tx what?
1st or 2nd Generation?

A

Schizophrenia

  • 2nd Generation
  • Both + & - S&S
25
Asenapine (Saphris) Tx what? 1st or 2nd Generation?
Schizophrenia - 2nd Generation - Both + & - S&S
26
Risperidone (Risperdel) Tx what? 1st or 2nd Generation?
Schizophrenia - 2nd Generation - Both + & - S&S
27
Paliperidone (Invega) Tx what? 1st or 2nd Generation?
Schizophrenia - 2nd Generation - Both + & - S&S
28
Lurasidone (Latuda) Tx what? 1st or 2nd Generation?
Schizophrenia - 2nd Generation - Both + & - S&S
29
Ziprasidone (Geodon) Tx what? 1st or 2nd Generation?
Schizophrenia - 2nd Generation - Both + & - S&S
30
Iloperidone (Fanapt) Tx what? 1st or 2nd Generation?
Schizophrenia - 2nd Generation - Both + & - S&S
31
``` Phenobarbital (Luminal) Class (2) Tx What? SE? Nursing considerations: ```
- anticonvulsant, barbiturate - generalized tonic-clonic, status epilepticus, partial, myoclonic, neonatal seizures - hangover, laryngospasms, angiodema, serum sickness (NOT suicidal ideation) - IV status epilepticus, dilute w/ NS PO maintenance 1st choice for seizures in neonates RISK OF LONGTERM COGNITIVE DYSFUNCTION 15-18 mg/kg IV
32
``` Phenytoin (Dilantin) Class (2) Tx What? SE? Nursing considerations: ```
- anti-convulsant, hydantoin - genralized tonic-clonic, status epilepticus, partial, - gingival hyperplasia, hirsutism, agranulocytosis (chk CBC) Rapid IV may cause severe hypOtension, CNS depression. - PO with or after food, IV undiluted 1-3 mg/kg & 50 mg/min INCOMPATIBLE WITH DEXTROSE! DO NOT GIVE WITH D5H20 ETC.
33
``` Carbamazepine (Tegretol) Class Tx What? SE? Nursing considerations: ```
- anticonvulsant generalized & partial seizures - drowsiness, ataxia, - Give with food, Q6-12 months CBC & LFT OK for kids under 6, weight dosing. 35 mg/kg
34
``` Gabapentin (Neurontin) Class (2) Tx What? SE? Nursing considerations: ```
- anticonvulsant, GABA analog - partial & general seizures - drowsiness, sedation - don't stop abruptly
35
``` The following drugs are use to Tx what? Carbamazepine (Tegretol) Clonazepam (Klonopin) Ethosuximide (Zarontin) Lamotrigine (Lamictal) Levetiracetam (Keppra) Oxcarbazepine (Trileptal) Phenobarbital (Luminal) Phenytoin (Dilantin) Topiramate (Topamax) Valproates (Depakeane, Depakote) ```
- seizures
36
Ethosuximide (Zarontin) | Used to Tx what type of seizure?
Absence | give with food
37
Clonazepam (Klonopin) | Used to Tx what type of seizure?
myoclonic, partial, atypical absence seizures
38
Lamotrigine (Lamictal) | Used to Tx what type of seizure?
ALL types of seizures
39
Levetiracetam (Keppra) | Used to Tx what type of seizure?
adjunct for partial add on therapy for generalized myoclonic epilepsy
40
Oxcarbazepine (Trileptal) | Used to Tx what?
Epilepsy in Children 2-16
41
Topiramate (Topamax) | Used to Tx what type of seizure?
MOST types of seizures (WTF!?!!) (Complete BS notes - thanks again Wake Tech!) Watch for kidney issues - care with Hx of renal calculi & Ketogenic diet
42
Valproates (Depakeane, Depakote) Used to Tx what type of seizure? Nursing considerations?
Generalized & Partial With or after food Q6-12 months CBC LFTs NOT for kids <2 years
43
``` Diazepam (Valium) Why given for seizures? Category (3) SE Order of preference for admin: 1, 2, 3 routes Nursing considerations? ```
- Stops seizures - benzodiazepine, anticonvulsant, sedative - RESP DEPRESSION - 1. IV, 2. IM, 3. PR - Children give over 3-5 min. Rpt Q 15-30 min up to 10 mg. Rpt 2-4 hours Adults 5 mg/min q 10-15 min total 30 mg
44
``` Why are these 3 meds given to pt. experiencing seizures? Which one is given via IV in the ICU? Diazepam (Valium) Lorazepam (Ativan) Midalozam (Versed) ```
Given to STOP seizures - follow with anti convulsant med. | - Lorazepam (Ativan)
45
Lorazepam (Ativan) Why given for seizures? Category (3) SE
- Stops seizures - benzodiazepine, antianxiety, sedative - RESP DEPRESSION, APNEA & CARDIAC ARREST with rapid IV admin
46
Which drug is preferred for status epilepticus & why?
Lorazepam (Ativan) | rapid onset, long 1/2 life
47
Midalozam (Versed) Why given for seizures? Category SE
Stops seizures - benzodiazepine, - RESP DEPRESSION, APNEA & CARDIAC ARREST