Exam 2

Question 1

Clomipramine (Anafranil)

Treats? Class? SE?

Answer 1

Treats OCD
Tricyclic Anti-Depressant
SE: cardiac

Question 2

These drugs are all \_\_\_\_\_? (category)
Citalopram (Celexa)
Escitalopram (Lexapro)
Fluvoxamine (Luvox)
Paroxetine (Paxil)
Fluoxetine (Prozac)
Sertraline (Zoloft)

Answer 2

Selective serotonin reuptake inhibitors (SSRIs)

Question 3

These drugs are all \_\_\_\_\_? (category)
Bupropion (Wellbutrin)
Nefazodone (Serzone)
Trazodone (Desyrel)
Buspirone (Buspar)

Answer 3

Atypical antidepressants

Question 4

These drugs are all \_\_\_\_\_? (category)
Mirtazapine (Remeron)
Duloxetine (Cymbalta)
Venlafaxine (Effexor)
Desvenlafaxine (Pristiq)

Answer 4

Dual Action Reuptake Inhibitors
SEROTONIN & NOREPINEPHRINE
SNRIs (Serotonin & norepi reuptake inhibs)

Question 5

These drugs are all _____? (category)
Atomoxetine (Strattera)
Reboxetine (Vestra)

Answer 5

Selective Norepinephrine Reuptake inhibitors

selective NRIs

Question 6

These drugs are all \_\_\_\_\_? (category)
Amitriptyline (Elavil
Maprotiline (Ludiomil)
Nortriptyline (Pamelor)
Protriptyline (Vivactil)

Clomipramine (Anafranil)
Desipramine (Norpramin)
Imipramine (Tofranil)
Trimipramine (Surmontil)

Amoxapine (Asendin)
Doxepin (Sinequan)

Answer 6

Tricyclic antidepressants (TCAs)

Question 7

These drugs are all \_\_\_\_\_? (category)
Isocarboxazid (Marplan)
Phenelzine (Nardil)
Tranylcypromine (Parnate)
Selegiline (Eldepryl, EMSAM)

Answer 7

Monoamine oxidase inhibitors (MAOIs)

Question 8

First-line mood stabilizing drugs (2)

Answer 8

Lithium Carbonate (LiCO3) 
Divalproex (Depakote)

Question 9

Olanzapine

• Class?
• Tx Mania or Depression?

Answer 9

• Class? Mood stabilizer

- Mania or hypomania

Question 10

Lithium Carbonate (LiCO3)

• Tx?
• How long B4 effects seen?
• Dose

Answer 10

• Acute Tx for mania and depressive episodes
  Prevention for recurrent mania and depressive episodes
• 10-21 days
• 600mg - 900mg PO BID or TID

Question 11

• Maintenance blood level of LiCO3?
• Toxicity level?
• Life threatening emergency level?

Answer 11

• 0.4 - 1.3 mEq/L
  -No greater than 1.5 mEq/L
  1.5 - 2.0 early Toxicity
  2 - 2.5 severe toxicity
• > 2.0 mEq/L

Question 12

Proscar (Finasteride)
Tx what?
Side effects?

Answer 12

Tx BPH
Side effects: Breast cancer/Allergic reaction
Impotence, loss of interest in sex, or trouble having an orgasm;
abnormal ejaculation;
swelling in hands or feet;
swelling or tenderness in breasts;
dizziness

Question 13

Drugs for Gallbladder:

1. Pain (2)
2. Anti-inflammatory
3. Anticholinergic/antispasmodics
4. (Not for which population?)

Answer 13

1. Morphine and dilaudid
2. Ketorolac(Toradol)
3. Dicyclomine (Bentyl, Lomine)
4. – not for older adults

Question 14

celexa

class?

Answer 14

SSRI

Question 15

lexapro

class?

Answer 15

SSRI

Question 16

luvox

class?

Answer 16

SSRI

Question 17

paxil

class?

Answer 17

SSRI

Question 18

prozac

class?

Answer 18

SSRI

Question 19

zoloft

class?

Answer 19

SSRI

Question 20

SE of all antidepressants may include:
1.
2.

Answer 20

Suicidal ideation

worsening depression

Question 21

Simple SE of TCAs include:

Answer 21

anticholinergic (can’t see, can’t pee, can’t spit. can’t shit)
tachycardia
postural hypotension

Question 22

TCAs work by inhibiting reuptake of ___ & ____

Answer 22

norepinephrine & serotonin

Question 23

Toxic effects of TCAs include:

Answer 23

CARDIOVASCULAR
dysrhythmia
tachycardia
MI 
heart block
Over dose is LETHAL

Question 24

Best time of day to take TCAs?

Answer 24

At night

Question 25

Simple SE of SSRIs include:

Answer 25

``` agitation Headache Nausea Sleeplessness OR daytime drowsiness tremors dizziness sexual dysfunction (decreased drive/ no orgasms :( autonomic SE including:dry mouth, sweating, weight changes, nausea, loose BM. ```

Question 26

``` The following are s/s of which drug side effect? They are caused by which class of drugs? Interactions with what may cause this? hyperactivity/restlessness, tachycardia, hyperpyrexia, elevated BP, AMS, hostility, mood change, seizures, muscle spasms (Myoclonus), abdominal pain, diarrhea, cardiovascular shock and may be incompatible with life! ```

Answer 26

serotonin syndrome SSRIs MAOIs Herbals such as St. John's Wort

Question 27

SE of atypical antidepressants:

Answer 27

Nausea, headache, anxiety, dizziness

Question 28

SE of SNRIs

Answer 28

nausea headache sexual dysfunction SIADH

Question 29

SE MAOIs general + Most severe!

Answer 29

``` HYPOTENSION sedation, weakness, fatigue insomnia changes in cardiac rhythm muscle cramps anorgasmia/impotence urinary hesitancy/constipation weight gain MOST SEVERE HYPERTENSIVE CRISIS ```

Question 30

These are what kinds of drugs? Used for what? Cimetidine (Tagamet) Famotidine (Pepcid) Nizatidine (Axid) Ranitidine (Zantac)

Answer 30

- H2-receptor blockers | - Peptic Ulcers

Question 31

These are what kinds of drugs? Used for what? ``` Dexlansoprazole (Dexilant) Esomeprazole (Nexium) Lansoprazole (Prevacid) Omeprazole (Prilosec) Pantoprazole (Protonix) Rabeprazole (Aciphex) ```

Answer 31

- proton pump inhibitors (PPI) | - Peptic Ulcers

Question 32

Bismuth is also known as_______.

Answer 32

Pepto-Bismol