exam 1 Flashcards

1
Q

You work in a lab. You engineer a mutant mouse that doesn’t synthesize a protein important for breakdown of the sugar galactose and study the results. What type of geneticist are you?

A

Molecular geneticist

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2
Q

Which of the following could be used to study the effects of drugs on gene expression?

A

molecular genetics

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3
Q

A cellular structure that contains genetic information is called a ___________.

A

chromosome

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4
Q

_______ is the use of the information in gene sequences to synthesize functional proteins that affect cellular characteristics.

A

Gene expression

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5
Q

Which one of the following is NOT one of the general classes of macromolecules that are necessary for cellular function?

A

ions

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6
Q

Genetic variation is ultimately based upon which of the following?

A

variations in nucleotide sequence of the DNA

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7
Q

Ball pythons of the same species can look very different from one another. In fact, there are at least 26 types of ball pythons, characterized by their color, eyes, and markings. The blue-eyed leucistic ball python has blue eyes and white scales. The bumblebee ball python has black and yellow scales. The coral glow ball python has purple and orange scales. What term best describes these different types of pythons?

A

Morphs

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8
Q

Chronic myelogenous leukemia cells are characterized by the so-called Philadelphia chromosome, which contains part of chromosome 22 fused with chromosome 9. The Philadelphia chromosome is the result of a translocation, in which two chromosomes exchange material. The genetic variation found in chronic myelogenous leukemia is therefore due to

A

major alterations in the structure of a chromosome.

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9
Q

What is the first step that both scientists and students perform to answer questions in genetics?

A

Gathering background information

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10
Q

Genetics is an experimental, as opposed to theoretical, science because ______.

A

hypotheses are tested by performing experiments

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11
Q

Which of the following would contain genetic material that is 100% identical?

A

sister chromatids

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12
Q

During this phase of the cell cycle, the sister chromatids are formed in eukaryotes.

A

S phase

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13
Q

A cytogeneticist would primarily do which of the following?

A

examine chromosomes using a karyotype

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14
Q

The location of a gene on a chromosome is called its _____________.

A

locus

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15
Q

The process of meiosis II is similar to that of __________.

A

mitosis

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16
Q

A species has a diploid number of 36. If meiosis didn’t occur, and gametes were produced by mitosis, each gamete would contain ______ chromosomes, and a fertilized egg would contain ______ chromosome.

A

36; 72

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17
Q

Select the phase when the chromosomes line up in the center of the cell.

A

Metaphase

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18
Q

Cytokinesis in animals occurs through the formation of a ______, whereas in plants a ______ forms.

A

cleavage furrow; cell plate

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19
Q

A pollen grain in a plant represents the ________.

A

male gametophyte

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20
Q

Oogenesis is a gametogenic process in which cells undergo ________ to produce _______.

A

meiosis; egg cells

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21
Q

What aspect of meiosis best explains Mendel’s law of independent assortment?

A

random alignment of different bivalents during Meiosis I

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22
Q

Which situation below would violate the law of independent assortment, as understood by Mendel?

A

A gene for leaf shape is linked to a gene for petal number nearby on the same chromosome, so their alleles usually segregate together.

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23
Q

Mendel’s law of independent assortment states that ______ randomly assort their ______ during the formation of haploid cells.

A

genes; alleles

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24
Q

An individual who has two identical alleles for a trait is said to be ___________.

A

homozygous

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25
The genetic composition of an individual is called its _____________.
genotype
26
If over several generations a character does not vary in a group of organisms, that group can be called a _______.
true-breeding line
27
Which of the following characteristics made the pea plant Pisum sativum an ideal organism for Mendel's studies?
It has the ability to self-fertilize. It was possible to cross-fertilize one plant with another. It has easily identifiable traits.
28
Recall that in pea plants, purple flower color is dominant and white is recessive. If two heterozygous plants are crossed, what is the probability that the first two offspring will have purple flowers?
9/16
29
The chance that a future event will occur is called ____________.
probability
30
In humans, patterns of inheritance are often studied using which of the following?
pedigree analysis
31
Who originally identified a highly condensed structure in the interphase of nuclei?
Barr and Bertram
32
What gene is most responsible for X-inactivation?
Xist
33
Dosage compensation offsets the problems associated with differences in the number of _______ chromosomes in many species.
sex
34
An example of a mechanism in which sex is determined by environmental factors is
fertilized eggs incubated at one temperature produce males, whereas eggs incubated at a different temperature produce females.
35
Sex determination in humans and Drosophila is similar in the fact that
males have one X chromosome and females have two X chromosomes.
36
A male that is produced from an unfertilized haploid egg is an example of what type of sex determination system?
haplo-diploid
37
If a gene is located on the X chromosome, but not the Y, it is said to be an example of ________.
sex-linkage
38
Brown spotting of the teeth in humans is caused by a dominant X-linked gene. If a man with normal teeth marries a woman with brown teeth who had a father with normal teeth, then _______ of their daughters will have brown teeth.
50%
39
Glucose-6-phosphate dehydrogenase deficiency (G6PDD) is an X-linked recessive disease. What is the probability that the brother of a girl with G6PDD will also have G6PDD if their mother is unaffected.
50%
40
The first person to experimentally determine that a trait is located on a specific chromosome was ____________.
Morgan
41
If a geneticist describes a trait as being 70% penetrant, what would that mean?
Only 70% of the individuals who have a particular genotype express the trait.
42
An experiment in which plants with the same genotype are raised under conditions that differ in soil quality could evaluate _____.
the norm of reaction
43
If a combination of two or more genes is required to produce a specific trait, it is called a(n) _______.
gene interaction
44
Epistasis occurs when the alleles of one gene mask the phenotypic effects of the alleles of another gene at a different locus. This phenomenon can be observed in the sweet pea, Lathyrus odoratus: C (one purple-color-producing) allele is dominant to c (white) P (another purple-color-producing) allele is dominant to p (white) cc or pp masks the P or C alleles, producing white color Determine the genotypic and phenotypic ratios of a cross between a purple and white sweet pea above.
1 CcPP (purple) : 1 CcPp (purple) : 1 ccPP (white) : 1 ccPp (white)
45
In overdominance, the _______ genotype is beneficial over the _______ genotypes.
heterozygous; homozygous
46
At the molecular level, type A and type B blood differ in which of the following characteristics?
the antigens present on the surface of the red blood cells the type of sugar found in each type the antibodies that are generated against the other type of blood
47
The alleles that cause Huntington disease in humans are an example of ____________.
lethal alleles
48
In rabbits, full coat color (C  ) is the dominant trait. A second allele, chinchilla (c ch ), is recessive to full coat color. Himalayan coat color (c h ) is recessive to chinchilla and full coat colors, and albino (c ) is recessive to all coat colors. If two chinchilla rabbits mate, what coat color is not possible in their offspring?
full coat color
49
If an allele is dominant in one sex and recessive in another, it is an example of ___________.
sex-influenced inheritance
50
The multiple effects of a single gene on the phenotype of an organism is called _______.
pleiotropy
51
What disease is associated with imprinting?
Angelman Syndrome
52
What is the type of inheritance that is based on a reversible modification of genomic DNA that results in the alleles of only one parent being transcriptionally active?
epigenetic
53
How is a chloroplast genome similar to a prokaryotic genome?
They are both circular.
54
What type of inheritance is observed with extranuclear DNA?
Cytoplasmic inheritance
55
Contribution of mitochondria by the sperm cell to the zygote is called
paternal leakage.
56
Diseases associated with mitochondria mutations in humans are usually
degenerative.
57
Which of the following is primarily responsible for the maternal effect?
nurse cells
58
If a snail that has a right hand twist and is DD is mated to a snail that has a left hand twist and is dd what is the expected ratio of progeny?
It depends on which parent snail is female and which is male.
59
The symbiotic relationship where one organism lives inside another species is called
endosymbiosis.
60
Mitochondria are thought to have originated from ______, and chloroplasts likely arose from ______.
purple bacteria; cyanobacteria