Exam 1 Flashcards
Pitocin MOA
Synthetic oxytocin
Stimulates uterine contraction (CTXN) and milk let-down
When is Pitocin used
Induction of labor
Postpartum hemorrhage (PPH)
Pitocin route and dosages
IV
Induction: 1-2 milliunits/min, increased every 15-20 mins
PPH: 125-200 milliunits/min or 10-20 units IM
Nursing considerations for Pitocin
Monitor FHT and CTXN q 15 mins
Monitor for uterine tachysystole - more than 5 contractions in 10 mins over 30 min window
Decrease Pitocin if uterine tachysystole or baby distress occurs
Cytotec (misoprostol) uses
Cervical ripening
Tx for postpartum hemorrhage
Cytotec (misoprostol) routes
Oral, vaginal, rectal
Cytotec (misoprostol) adverse effects
H/A
N/V/D
Fever/chills
Nursing considerations for Cytotec (misoprostol)
For:
Cervical ripening - continuous fetal monitoring
Postpartum hemorrhage (PPH) - monitor vaginal bleeding and uterine tone
Methergine (methylergonovine) uses
Tx of uterine atony (soft uterus) and PPH (postpartum hemorrhage)
Methergine (methylergonovine) route and dose
0.2 IM q 2-4 hours
Up to 5 doses
Methergine (methylergonovine) adverse effects
HTN & hypotension
N/V
H/A
Tinnitus
Dizziness
Contraindications for Methergine (methylergonovine)
HTN or pregnancy induced HTN - AE
Preeclampsia
CVD
Lactation
Nursing considerations for Methergine (methylergonovine)
Check BP before giving (do not give if >140/90)
Monitor vaginal bleeding and uterine tone (therapeutic effect)
Hemabate (carboprost/15methyl pg f) uses
Postpartum uterine bleeding r/t uterine atony
Hemabate (carboprost/15methyl pg f) route and dose
0.25 mg (250 mcg) IM q 15-90 mins
Hemabate (carboprost/15methyl pg f) adverse effects
Explosive diarrhea
N/V
H/A
Fever/chills
Tachycardia
HTN
Contraindications for Hemabate (carborprost/15methyl pg f)
Asthma
HTN
Cardiac, pulmonary, or hepatic disease
Nursing considerations for Hemabate (carboprost/15methyl pg f)
Administer with antidiarrhea (adverse effect)
Monitor vaginal bleeding and uterine tone (therapeutic effect)
TXA (Tranexamic acid) use
PPH
TXA (Tranexamic acid) route and dose
1g slow IV injection
Mixed with 50 or 100 mL IVF
- Administer over 10 minutes
TXA (Tranexamic acid) adverse effects
Hypotension
Visual abnormalities
N/V/D
Anaphylaxis
Contraindications for TXA (Tranexamic acid)
Hx or risk of thromboembolic disease
Caution with pt with renal impairment
Nursing considerations for TXA (Tranexamic acid)
Monitor hemodynamic - assessing for thromboembolic events (contraindication)
Magnesium sulfate MOA
CNS depressant
Relaxes smooth muscle - uterus