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Flashcards in Exam 1 Deck (84)
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1

What is etiology? And what are the risks

Origin of disease "why"
Risks are inherited or environmental

2

What is pathogenesis?

Steps in development "how"

3

What are morphological changes?

They can be gross or microscopic, biochemical, structural, functional

4

What describes how a disease develops and outlines the steps of development, such as cellular and molecular changes

Pathogenesis

5

Cardiac myocytes undergo what to compensate for chronic hypertension

Hypertrophy

6

What is the term indicating an increase in the number of cells

Hyperplasia

7

A viral infection that results in a wart formation is an example of pathological...

Hyperplasia

8

Diminished blood supply or loss of innervation to a cell are most likely to produce....

Atrophy

9

Decreased cellular protein synthesis combined with increased protein degradation is the hallmark feature of what

Atrophy

10

What involves replacing one adult cell type with another adult cell type

Metaplasia

11

What adaptation to stress increases the likelihood of developing cancer

Metaplasia

12

True or False, a cell that has been injured will always die as a result

False

13

Is inflammation associated with necrosis or apoptosis

Necrosis

14

Which pattern of tissue necrosis requires a histologic exam

Fibrinoid necrosis

15

What term describes destructive fragmentation of the nucleus within a dying cell?

Karyorrhexis

16

Hypoxia to neurons within the CNS are likely to produce

Liquefactive necrosis

17

Is timing of the injury impactful in cellular response to injurious stimuli?

No; duration, type, and severity are much more impactful

18

True or False; mitochondria are resistant to the deleterious effects of hypoxia

False

19

An influx of intracellular calcium will stimulate what by activating caspases?

Apoptosis

20

True or False; reactive oxygen species are produced in all cells during normal aerobic respiration

True

21

True of false; reactive oxygen species are the most damaging to mucous membranes

False

22

What term describes nuclear shrinkage within a dying cell?

pyknosis

23

What term describes nuclear fading within a dying cell?

Karyolysis

24

True or False; ischemia to a tissue will inhibit oxidative phosphorylation as well as glycolysis

True

25

Prolonged ischemia that produces irreversible cellular injury will stimulate what?

Necrosis

26

Restoration of blood flow to ischemic tissue is most likely to cause damage to what kind of tissue?

Myocardium

27

Accumulation of triglycerides within hepatic parenchyma is termed what?

Steatosis

28

Deposition of calcium into necrotic tissue is termed what?

Dystrophic calcification

29

Pathological hypercalcemia causing deposition of calcium into normal tissues is termed what?

Metastatic calcification

30

What involves telomeres shortening and limiting the capacity fro the cell to replicate

Replicative senescence