Exam 1 Flashcards

(74 cards)

1
Q

A disease caused by fat accumulation in the liver

A

• Non-Alcoholic Fatty Liver Disease

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2
Q

Population of people highly affected by diabetes

A

• American Indian

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3
Q

Cells of the liver

A

• Hepatocytes

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4
Q

A form of diabetes that occurs during pregnancy

A

• Gestational

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5
Q

The most common form of diabetes

A

• Type 2

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6
Q

Looks at the rise and fall of glucose and is used to diagnose diabetes

A

• Glucose Tolerance Test

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7
Q

The type of cell that secretes glucagon

A

• Alpha

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8
Q

Once insulin binds to the cell, what comes to the surface to allow glucose to enter?

A

• Glucose Transporter

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9
Q

Looks at glycalated hemoglobin

A

• A1C

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10
Q

What cycle does glucose go into after entering the cell?

A

• Glycolysis

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11
Q

The hormone that is elevated during starvation or fasting

A

• Glucagon

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12
Q

Type of diabetes that is immune to insulin

A

• Type 1

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13
Q

Cluster of cells in the pancreas that contains alpha and beta cells

A

• Islet of Langerhans

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14
Q

Type 2 diabetes is characterized by a state of..

A

• Insulin resistance

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15
Q

The type of cell that secretes insulin

A

• Beta

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16
Q

Insulin binds here to start glucose intake

A

• Insulin receptor

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17
Q

Ketone synthesis

A

• Ketogenesis

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18
Q

The energy of the cell

A

• ATP

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19
Q

The process of making glucose in the liver

A

• Gluconeogenesis

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20
Q

Condition of having too much glucose in the blood

A

• Hyperglycemia

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21
Q

When do beta cells stop growing?

A

• Puberty

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22
Q

The hormone needed for the uptake of glucose

A

• Insulin

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23
Q

Released from fat and are part of the proposed mechanism of insulin resistance

A

• Cytokines

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24
Q

A cholesterol like molecule that helps in fat digestion and could be involved in insulin

A

• Bile salts

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25
Where transcription occurs
Nucleus
26
amino acid codon GGU
Glycine
27
a mutation that is a result of one base being altered
Point
28
start codon
AUG
29
a mutation that causes the reading frame if the genetic code to be misread
frameshift
30
all your DNA collectively
Genome
31
scientist known for discovery of DNA
Watson
32
unique absence of 3 bases
codon
33
proteins are made of
amino acids
34
type of bond between bases of DNA
Hydrogen
35
nucleic acid composed of 2 strands- your genetic material
DNA
36
a mutation that doesn't change the protein
silent
37
a mutation that occurs when a base is swapped for another base
substitution
38
where transcription stops
terminator
39
a gene that is always turned on an maintains normal activity
housekeeping
40
where translation occurs
ribosome
41
enzyme required for transcription
polymerase
42
the process of making RNA
transcription
43
main difference between DNA and RNA
sugar
44
where a ribosome is located
endoplasmic reticulum
45
a mutation that is a result of a base removed
deletion
46
coding regions in DNA
exons
47
substances that cause mutations
mutagen
48
process of making proteins
translation
49
single stranded nucleic acid that is a copy of DNA
RNA
50
previously thought of as your genetic material in the 1930's
proteins
51
a segment of DNA that codes for a trait
gene
52
DNA must be _______ prior to transcription
unwound
53
what is the #1 cause of death in US
Heart disease
54
_____ refers to the number of persons with a disease at any one time
Prevalence
55
a disease that causes lesions is classified as
structural
56
what is used for energy in the cell
ATP
57
I haven't been feeling well. What is this called for a clinician
symptom
58
what drug targets AMPK and is the most prescribed class of drug
biguanide
59
someone who performs autopsies
anatomic pathologist
60
which occurs most frequently
type 2
61
the central dogma of genetics is
DNA -->RNA --> protein
62
______ are health problems that interfere with a person's ability to function
disbilities
63
why do some T2DM need insulin therapy
Beta cells die out
64
which is NOT a symptom of T2DM
decreased urine output
65
someone's entire genetic code is known as
genome
66
a cell in the fat/adipose tissue is called
adipocyte
67
what method involves using scientific literature, clinical knowledge, and a patient's ideas/wishes
Evidence-based medicine
68
what molecule starts the process of insulin secretion
glucose
69
what tissue secretes insulin
pancreas
70
main cause of T2DM
genetics, bad eating habits, sedentary lifestyles
71
following eating, which statement is true
insulin goes up, blood glucose goes down
72
which type of diabetes is characterized as insulin resistant
type 2
73
a muation masked because the code is degenerative and doesn't affect the amino acid sequence. this is a _____ mutation
silent
74
how many amino acids are there
20