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1

Regulates NP prescriptive authority

State Board of Nursing

2

APRNs care for the patient from a

holistic approach and include the patient in decision making regarding their care

3

Clinical judgement in prescribing includes:

factoring in the cost to the patient of the medications prescribed

4

Criteria for choosing an effective drug for a disorder include:

consulting nationally recognized guidelines for disease management

5

The time required for the amount of drug in the body to decrease by 50%

Half-life

6

When prescribing based on schedule, be aware of:

half-life

7

After four to five half-lives, what does a drug reach?

Steady state

8

Drugs that have a significant first-pass effect are

rapidly metabolized by the liver and may have little if any desire action

9

Drugs metabolized in the liver by phase I or phase II reactions

change drug molecules to a form that an excretory organ can excrete

10

Hypoalbuminemia

May affect the distribution of drugs to target tissues

11

Bioavailability issues are especially important for drugs with:

narrow therapeutic ranges or sustained-release mechanisms

12

CYP3A4 enzyme can:

induce or inhibit metabolism of another drug

13

Grapefruit juice contains furanocoumarins that have been found to:

inhibit CYP3A4, leading to decreased first-pass metabolism

14

To achieve the best effect, take enteric-coated tablets with:

at least 8 ounces of fluid

15

If crushed could possibly result in toxicity

sustained-release capsules

16

What is an advantage of sublingual medication?

Absorbed rapidly

17

Factors that affect gastric drug absorption include:

lipid solubility of the drug

18

A rich blood supply to the area of absorption leads to:

better absorption

19

Treatment goals in prescribing should always be:

patient-centered

20

Therapeutic goals when prescribing include:

curative, palliative, preventative

21

When determining drug treatment, the NP should:

individualize the drug choice for the specific patient

22

Patient education regarding prescribed medications includes:

discussion of expected adverse drug reactions

23

What is passive monitoring?

Instructing the patient to report if the drug is not effective

24

Who regulates the official labeling for all prescription and OTC drugs?

FDA

25

FDA approval is also required for:

medical devices

26

Off-label prescribing is legal if:

there is scientific evidence to support use

27

Which drugs require a new prescription each month?

Schedule II drugs

28

Which scheduled drugs cannot be faxed to the pharmacy?

Schedule I and II

29

Which scheduled drugs can be faxed to the pharmacy?

Schedule III-V

30

What are some strategies to prevent misuse of controlled prescription drugs?

Limit-setting, chemical dependency screening tools, and practicing "just say no"