Exam 1-Cells Matrix, Ossification, Bone Density, Bone Variation Flashcards

1
Q

The four basic tissues of the human body

A

epithelial
muscle
neural
connective tissues

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2
Q

What is osetology?

A

the study of bone

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3
Q

The three primary cell types of bone

A

osteoblasts, osteocytes, and osteoclasts

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4
Q

The function of each cell type

A

osteoblasts-form bone
osteocytes-maintain or nuture bone
osteoclasts-remodel bone

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5
Q

What are bone cells embedded in?

A

an amorphous matrix consisting of ground substance, protein fibers, and various materials

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6
Q

What is the primary constituent of the ground substance?

A

glycosaminoglycans

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7
Q

What types of glycosaminoglycans dominate in bone?

A

chondroitin sulfate, keratin sulfates and hyularonic acid

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8
Q

What is the principal type of protein fiber in bone?

A

collagen type I

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9
Q

What are the primary constituents of bone mineral?

A

calcium, phosphate, citrate and carbonate ions

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10
Q

What is the most frequently described deposit in bone?

A

hydroxyapatite

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11
Q

Bone is also the repository for what additional ions?

A

sodium, magnesium, fluoride, lead, strontium, and radium

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12
Q

What is wolff’s law as it pertain’s to bone?

A

living tissue will respond to stressors; boen is formed or absorbed in response to stress

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13
Q

What are the three responses of bone that allow it to be described as “living”?

A

ability to heal, to remodel, and to age

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14
Q

What is the name given to the pattern of ossification in mesenchyme?

A

intramembranous ossification

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15
Q

What is the timing for the apperance of intramembranous ossificaiton?

A

from the second to third month in utero

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16
Q

What is the name given to the pattern of ossification in cartilage?

A

endochondral ossification

17
Q

What is the timing for the apperance of endochondral ossification?

A

from the second to fifth month in utero

18
Q

What part of the skull is derived from endochondral ossificaiton?

A

chondocranium

19
Q

Which bone of the appendicular skeleton is formed by both endochondral and intramembranous ossification?

A

the clavicle

20
Q

What are the names given to the center of ossificaiton based on time of apperance?

A

primary centers of ossification before birth

secondary centers of ossificaiton after birth

21
Q

Mature bone is described as being composed of what areas based on bone density?

A

cortical or compact bone and spongy, cancellous or trabecular bone

22
Q

What is the name given to bone below the articular surface?

A

subchondral bone

23
Q

What is the name of the outer fibro-cellular covering of bone?

A

the periosteum

24
Q

What is the name given to the fibro-cellular lining of bone?

A

the endosteum

25
Q

What is the primary source of variation observed in bone?

A

sexual dimorphism (gender variation), ontogenetic variation (growth or age variation), geographic or population-based variation (ethnic variation) and idiosyncratic variation (individual variation)