Exam 1: CH 2, 16, 20 Flashcards

(63 cards)

1
Q

Patient refuses tablets stating she cannot swallow pills. What will the nurse do?

A

Call pharmacy and ask for the liquid form

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2
Q

Study of what the BODY does to the DRUG

A

Pharmacokinetics
- absorption (first pass effect)
- distribution (albumin)
- metabolism (liver)
- excretion (kidneys)

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3
Q

study of what the DRUG does to the BODY

A

PharmacoDynamics

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4
Q

clinical use of drugs to prevent and treat diseases

A

Pharmacotherapeutics

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5
Q

science of the adverse effects of drugs and other chemicals on living organisms

A

Toxicology

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6
Q

Study of natural vs synthetic drug sources

A

Pharmacognosy

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7
Q

When a drug is absorbed orally, in the gastric mucosa, or small intestine

A

Enteral route
- oral
- sublingual
- buccal
- rectal

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8
Q

route of drug given Intravenously

A

Parenteral Route

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9
Q

Nurse preparing to administer transdermal patch and finds the patient already has one. What will the nurse do?

A

remove old patch and apply new patch to a different clean area

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10
Q

Type of Route
medication given by Skin, Eyes, Ears, Nose, Lungs (inhalation), Rectum, Vagina

A

Topical

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11
Q

what is Cytochrome P-450 important for?

A

Metabolism of drugs

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12
Q

Physiologic state in which the amount of drug removed via elimination is equal to amount of drug absorbed with each dose

A

Steady state

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13
Q

Healthcare provider has changed route from PO to IV, what can the nurse expect with the IV dose?

A

IV Dose will be lower because of first pass effect

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14
Q

What is the extent of drug absorption?

A

Bioavailability

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15
Q

Route for slowest pain relief?

A

PO or Mouth

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16
Q

A patient is taking Buspirone, the nurse interprets that the patient may have which disorder?

A

Anxiety Disorder

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17
Q

Before beginning a patients therapy with SSRI’s, the nurse will assess for concurrent use of which medications?

A

Warfarin

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18
Q

When a patient is receiving a second gen antipsychotic drug, like risperidone, the nurse will monitor for which therapeutic effect?

A

Decreased paranoia and delusions

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19
Q

involuntary motor symptoms
parkinson’s
tardive dyskinesia
akathisia
tremors

A

Extrapyramidal Symptoms
(EPS)

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20
Q

NO TYRAMINE WHILE TAKING _____?

A

MAOI’s
no fermented food or drink
including alcohol

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21
Q

What are correct lithium levels?

A

0.6-1.2

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22
Q

common adverse effect of phenothiazines? (antipsychotic drug)

A

dry mouth

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23
Q

AVOID TAKING ST. JOHN’s WORT while taking ______.

A

SSRI’s

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24
Q

while monitoring a depressed patient who has just started SSRI’s the nurse will observe for what problem during the early time frame?

A

self injury or suicidal tendencies

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25
a patient has been admitted to the emergency department with suspected overdose of a Trycyclic antidepressant (TCA’s) the nurse will prepare for what immediate concern?
Cardiac Dysrythmias
26
how long does it take for patients to notice any therapeutic effects?
4-6 weeks
27
CLOZAPINE is an ______ drug, monitor for what adverse effect?
Antipsychotic, Severe neutropenia
28
With MAOI’s avoid processed meats and foods with tyramine. for example
Salami sandwich
29
A patient wants to take ginseng supplement, the nurse instructs the patient to look for which potential adverse effect?
Palpations and anxiety
30
What are symptoms of serotonin syndrome?
Agitation Tremors SWEATING
31
Trycyclic antidepressants cause serious cardiac dysrythmias if what happens?
Overdose
32
Which statements are true regarding the SSRI’s?
Therapeutic effects may not be seen for about 4-6 weeks after the medication starts
33
Anti Anxiety Drugs
Benzo’s -pam Alprozolam Lorazepam Diazepam
34
Anti- Anxiety (Benzo) Adverse Effects & Overdose Antidote
SEDATION Drowsiness loss of coordination ANTIDOTE for Benzo OD - Flumazenil (Romazicon)
35
Buspirone is also an anti-anxiety medication but is not a _______?
Benzo
36
Mood Stabilizing Drug?
Gabapentin Lithium - Sodium levels checked with this
37
SNRI Drug Ex. Adverse Effects
Cymbalta GI Upset anorexia
38
Lithium Level therapeutic range with Sodium normal range
0.6-1.2 135-145
39
most serious adverse effect of Lithium?
cardiac dysrthymias
40
Anti Depressant drugs SSRI’s Adverse effects
Paxil Zoloft Prozac Citalopram Serotonin Syndrome
41
Anti-Cholinergic drugs (ACh) **BOATS** **end in -ine**
Benztropine Oxybutanine Atropine Scopolamine
42
Tricyclic Antidepressants (TCA) Drug and Adverse effects
Ex. Amitriptyline - hypotension - constipation ANTICHOLINERGIC - dry you out no see, no pee, no spit, no sh!t
43
MOAI’s Drug examples AVOID what?
Nardil Parnate Marplan avoid tyramine, can cause hypertensive crisis
44
Serotonin Syndrome Symptoms
Agitation Tachycardia Sweating Muscle Spasms
45
Antidepressant interactions Highly Protein bound (W______) Avoid herbal products like _______
(warfarin) St. John’s Wort
46
Antipsychotic Drugs Adverse Effects Worst Case Scenario
Haldol, Seroquel, Abilify **Tranquilizing effect** adverse effect: EPS (extrapyramidal symptoms) - tardive dyskinesia - akathisia - parkinson’s WORST CASE SCENARIO- NMS (neuroleptic malignant syndrome)
47
Positive and Negative Symptoms of schizophrenia
+ : hallucinations, delusions - : isolation, poverty of speech,
48
which pneumonic for Anti-Cholinergic Drugs? Dry you out
BOAtS Benztropine Oxybutanine Atrophine Scopolamine
49
mnemonic for Cholinergic Drugs Example of Drug
SLUDGE salivation, lacrimation, urination, defacation, GI upset, Emesis Ex. Pilocarpine - Glaucoma
50
patient has been taking a cholinergic drug for 3 days and is experiencing Flushed Skin, BP changes, abdominal cramps, Nausea. What is patient experiencing?
Early signs of Cholinergic Crisis
51
Cholinergic Drugs are part of Parasympathetic Nervous System (rest and digest) fight or flight. What do they do?
S.L.U.D.G.E. increase excretions
52
Cholinergic Drugs can temporarily aid patients experiencing Myasthenia Gravis what are some examples of this drug? -stigmine Adverse effects?
pyridostigmine neostigmine physostigmine Adverse effects: Bradycardia, vomiting, hypotension
53
What can be used to treat cholinergic crisis in early phase?
atropine
54
ginko interacting with NSAID’s are known for causing _____?
internal bleeding
55
What is the common use for herbal Ginko? Adverse Effects Potential drug interactions
Common uses - prevent memory loss, vertigo Adverse effects - headache, bleeding, GI Upset POTENTIAL INTERACTIONS - NSAIDS, aspirin,
56
Perform baseline assessment of vital signs and overview systems before giving _________?
cholinergic drugs
57
Drugs should be taken how many minutes before eating?
30 minutes
58
What can be given to reverse effects of an overdose of a cholinergic drug?
Atropine
59
patient presents with sudden onset of muscle madness, drooling, and inability to articulate words. after ABC’s are stabilized, what history should the nurse gather?
information that aids in distinguishing cholinergic crisis from other issues
60
To differentiate between disease exacerbation and cholinergic crisis, what medication will the nurse administer?
pyridostigmine
61
what is reversal agent for pyridostigmine?
Atropine
62
What disorder does a patient most likely have if they are taking Pilocarpine?
Glaucoma
63
Killer B’s
Bradycardia - slow heartbeat Bronchospasm - spasm of bronchial Bronchorrhea - water sputum