Exam 1: final review Flashcards

(37 cards)

1
Q

A variation of a gene is called an ________

A

allele

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2
Q

a piece of DNA that encodes many proteins and functional RNAs and is bound tightly during mitosis is called _________

A

a chromosome

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3
Q

if a geneticist is studying the prevalence of a trait in a species they are at the ___________ level of study

A

population

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4
Q

which of the following is not a component of the DNA or RNA backbone?
A. ribose
B. phosphate
C. nucleotide bases
D. deoxyribose

A

C. nucelotide bases

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5
Q

the probability that a seed pod has a yellow seed and then a green seed and then two yellow seeds and then a green seed can be calculated using __________

A

the product rule

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6
Q

which of the following statements regarding natural selection are true?
A. genotypes increasing in frequency in a population are under negative selection
B. gene sequences in organisms must change for natural selection to occur
C. selection strength is not affected by the environment
D. phenotype must be affected for natural selection to act on genetic changes

A

A. phenotype must be affected for natural selection to act on genetic changes

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7
Q

In humans, patterns of inheritance are often studied using which of the following?
A. A dihybrid testcross
B. self-fertilization
C. producing true breeding lines
D. pedigree analysis
E. none of the above

A

D. pedigree analysis

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8
Q

using mendels flower color (purple is dominant, white is recessive), if two heterozygous plants are crossed, what is the probability that the first two offspring will have purple flowers

A

56.25% or 9/16

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9
Q

what genotype/phenotype would you use to perform a testcross to determine an unknown genotype of two traits in an organism

A

double homozygous recessive

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10
Q

The advantage of ___________ is short read, but huge amounts of data
The advantage of ___________ is longer reads, less data and more costly, also more time consuming
The advantage of ___________ is only single DNA sequences at once, very specific, bases added one at a time

A

Illumina
Roche 454
sanger dideoxy sequencing

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11
Q

which of the following would contain the same genes, in the same order but are not 100% identical
A. sister chromatids
B. homologous chromosomes
C. Chromosome 3 from a chimp and human
D. all answers are correct

A

B. homologous chromosome

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12
Q

What is the mRNA sequence from this coding strand of DNA:
5’ CGTAAGTA 3’

A

5’ CGUAAGUA 3’

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13
Q

which of the following phenomena results in the largest change in genome size?
A. Polyploidization
B. Gene Loss
C. Horizontal gene transfer
D. gene family expansion

A

polyploidization

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14
Q

which of the following statements about bacteria are true?
A. bacteria usually have nuclei
B. bacterial chromosomes are usually larger than most animal chromosomes
C. bacterial chromosomes are usually circular
D. bacteria usually have multiple chromosomes

A

C. bacterial chromosomes are usually circular

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15
Q

Which protein unwinds the DNA during DNA replication?

A

DNA helicase

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16
Q

Which group of organisms has the highest percentage of functional, transcribed DNA?

17
Q

Where is extranuclear DNA located in mammalian cells?

A

mitochondrion

18
Q

which of the following processes depends on complementary base pairing?
A. protein translation
B. RNA transcription
C. hybridization
A. all of the above

A

all of the above

19
Q

Alternative splicing refers to the process where multiple _________ are produced from one __________. This process is most common in ________, occurs less frequently in ___________ like C. elegans, and does not happen in ___________.

A

gene products, gene, mammals, nematode, bacteria

20
Q

T/F: after the DNA copy checkpoints and proofreading is complete, DNA replication is perfect

21
Q

T/F: when Mendel published his work it was an immediate success and changed science. He died a hero to science

22
Q

T/F: When the word “dominant” is used to describe an allele, it is the allele that will be expressed in a heterozygote and it will eventually go to fixation in a population

23
Q

Mendel’s law of segregation refers to the fact that the two alleles for a gene in a diploid organism separate during gamete formation and each gamete receives only one of these alleles

24
Q

T/F: genome size and chromosome number do not increase with organism complexity when looking at the whole picture of life

25
T/F: understanding genetics is critical to understanding all biological fields
true
26
__________ genes in different species that evolved from a common ancestral gene by speciation
ortholog
27
_________ is a type of mutation in which a base is lost and a frameshift is caused in the ORF
deletion
28
___________ obtaining a genetic sequence using DIdeoxy terminators, best for single genes across diverse taxa, not whole genomes
sanger sequencing
29
__________ the set of observable characteristics of an individual resulting from the interaction of its genotype with the environment
phenotype
30
_________ defines the probable origin of the mitochondrion and chloroplast
endosymbiosis theory
31
__________ alleles not expressed in a heterozygous locus
recessive
32
__________ adenine and guanine
purines
33
__________ genes in a single genome that evolved from a common ancestral gene by gene duplication
paralog
34
framework of genetic information going from DNA to protein
central dogma of molecular biology
35
_____________ fluorescent in-situ hybridization
FISH
36
_____________ a protein that binds to DNA and regulates gene expression by promoting or supressing transcription
transcription factors
37
______________ the genetic makeup of an organism
genotype