Exam 1: Gram Positive Corynebacterium Flashcards

1
Q

Gram positive, non-motile pleomorphic bacteria

A

Corynebacterium

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2
Q

T/F. Corynebacterium are obligate aerobes.

A

F. aerobic or facultative anaerobic

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3
Q

T/F. corynecacterium are non-spore forming

A

T

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4
Q

T/F. Corynebacterium contain short mycolic acids in their cell wall

A

T

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5
Q

Where are corynebacterium commensals?

A

mucus memb.

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6
Q

Corynebacterium are opportunistic pathogens causing mostly _____ infections.

A

Pyogenic

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7
Q

Gram positive aerobes with an unusual lipid rich outer layer which tend to survive in macrophages

A

Corynebacterium

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8
Q

Virulence factor of corynebacterium that protects from hydrolytic enzymes in host phagocytes

A

External lipid coat

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9
Q

virulence factor of corynebacterium used to hydrolyze cell membranes

A

Exotoxin Phospholipase D

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10
Q

Virulence factor of Corynebacterium that interferes with protein synthesis incells

A

Diphtheria toxin

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11
Q

What are the 4 species of Corynebacterium important in vet med?

A
  1. C. pseudotuberculosis
  2. C. bovis
  3. C. renale group
  4. C. kutscheri
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12
Q

What are the 2 species of Corynebacterium renal group?

A
  1. C. renale
  2. C. pilosum
  3. C. cystitidis
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13
Q

Caseous lymphadenitis in sheep and goats is caused by ____

A

Corynebacterium pseudotuberculosis

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14
Q

Chronic pyogranulomatous infection of lymph nodes of sheep and goats

A

Caseous lymphadenitis

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15
Q

What is Thin ewe syndrome?

A

internal abscesses leading to chronic wt. loss due to Corynebacterium pseudotuberculosis infection.

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16
Q

T/F. Caseous lymphadenitis is considered a curable disease?

A

F

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17
Q

What causes ulcerative lymphangitis in horses?

A

Corynebacterium pseudotuberculosis

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18
Q

Infectious, inflamatory condition of the cutaneous lymphatic system of lower limbs and chronic abscesses in the pectoral an ventral region of horses

A

Ulcerative lymphangitis caused by corynebacterium pseudotuberculosis

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19
Q

What are the 2 categories of Corynebacterium pseudotuberculosis?

A
  1. Non-nitrate reducing biotype

2. Nitrate reducing biotype

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20
Q

Caseous lymphadenitis in sheep and goats is cause by which category of corynebacterium pseudotuberculosis?

A

Non-nitrate reducing biotype

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21
Q

Ulcerative lymphangitis in horses is caused by which category of Corynebacterium pseudotuberculosis

A

Nitrate reducing biotype

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22
Q

Horse presents with the following signs:

selling of chest, fever, loss of app., lameness, external abscesses

A

Ulcerative lymphangitis caused by Corynebacterium pseudotuberculosis

23
Q

What are other names of Ulcerative lymphangitis?

A

pigeon fever

dry-land distemper

24
Q

T/F Ulcerative lymphangitis in horses is common in wet areas?

A

F. Dry

25
Q

Ulcerative lymphangitis is a seasonal incidence. When is it most prevalent?

A

autumn and early winter

26
Q

What insects play a role in the dissemination of Corynebacterium pseudotuberculosis?

A

Stable flies, horn flies, house flies

27
Q

Inflammation of the urinary bladder that may ascend the ureters to cause infection of the kidneys in cows.

A

Contagious bovine pyelonephritis

28
Q

What organisms cause Contagious bovine pyelonephritis?

A
  1. Corynebacterium renale
  2. Corynebacterium cystiditis
  3. Corynebacterium pilosum
29
Q

What is the reservoir of corynebacterium renal group in cows?

A

vulva and vagina of carriers

30
Q

Cow presents with:

fever, loss of app., painful urination, urine odor, abbdominal pain, dec. milk production

A

Contagious bovine pyelonephritis cause by Corynebacterium renal group

31
Q

Diseas of lab animals caused by Corynebacterium kutscheri.

A

Murine pseudotuberculosis

32
Q

Gram positive bacteria occuring as cocci or rods

A

Rhodococcus

33
Q

T/F. Rhodococcus are strongly acid fast

A

F. weakly

34
Q

Opportunistic pathogen of young foals that survive in macrophages with granular formation

A

Rhodococcus

35
Q

T/F. Rhodococcus are obigate intracellular pathogens

A

F. facultative intracellular

36
Q

The main respiratory pathogen of foals under 6mo?

A

Rhodococcus

37
Q

Why are foals most susceptible to suppurative bronchopneumonia caused by Rhodococcus?

A

bacterial-directed inappropriate Th2 rather than Th1 based immune response and impaired cellular immunity in the lungs

38
Q

Virulence factor of Rhodococcus that promotes survival in non-activated macrophages

A

vapA protein

39
Q

Virulence factor of Rhodococcus that retards phagocytosis

A

Capsular polysaccharides and mycolic acid

40
Q

How do foals become infected with rhodococcus

A

inhalation

41
Q

What are some factors that inc. the chances of foals becoming infected with rhodococcus?

A
  1. Dry weather
  2. High foal density
  3. Poor grass cover on paddocks
  4. Large number of horses on farm
42
Q

What species can be infected with rhodococcus equi?

A

Foals, pigs, cattle, cats

43
Q

Bronchopneumonia and lung abscessation in foals, 1-4 mo.

A

Suppurative bronchopneumonia of foals caused by Rhodococcus equi

44
Q

Foal presents to with:

fever, anorexia, diarrhea, cough, and dyspnoea

A

Suppurative bronchopneumonia of foals caused by Rhodococcus equi

45
Q

Gram positive, pleomorphic, aerobic, bacteria. may be cocci or rods with characteristic long branching filaments

A

Nocardia

46
Q

T/F Nocardium are facultative intracellular bacterium and acid fast partial

A

T

47
Q

Where is Nocardia commonly found in the environment?

A

Soil and water

48
Q

T/F. Nocardia are pathogenic even in immunocompetent animals

A

F. non- pathogenic

49
Q

What are the 3 forms of Nocardiosis in dogs?

A
  1. Thoracic
  2. Cutaneous
  3. Disseminated
50
Q

What is the form of Nocardiosis in cows?

A

Mastitis

51
Q

What form of nocardiosis causes fibrovascular proliferative reaction on pleura and accumulation of fluid in the thoracic cavity of dogs

A

Thoracic form

52
Q

What form of Nocardiosis causes ulcers on the skin of dogs

A

Cutaneous

53
Q

What is bovine nocardial mastitis?

A

Chronic mastitis with multifocal fibrosis in affectd gland caused by Nocardia