Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

ANSC 333 > Exam 1 - Lecture 3 > Flashcards

Exam 1 - Lecture 3 Flashcards

(63 cards)

Start Studying
1
Q

A protein which binds a corresponding molecular ligand conferring biological
activity

A

Receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

A molecule which binds to the receptor to elicit a response

A

Agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Interacts with the receptor to block or inhibit the effects of the ligand

A

Antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Agonist: acts like a natural —-

Antagonist: —- signal transduction

A

ligand
block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Receptors confer ________ and _________

A

Specificity and Activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Hormones require ——– to induce an effect

A

Receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The abundance and accessibility of these receptors dictates the local
___________ of biological activity

A

intensity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How to increase the intensity of signals?

A

Increase hormones and increase of receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Steroid hormone action: —- receptor binds to steroid hormone
—- to nucleus.
—- binding domain binds to specific HRE of DNA.
—- occurs. (this is how steroid hormones modify —-)

A
  • Cytoplasmic
  • Translocate
  • DNA
  • Dimerization
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the three members of the Nuclear Receptors

A
  • Androgen receptors
  • Estrogen Receptors
  • Progesterone Receptors
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

ramp up the gene

A

Androgen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

turns the gene off

A

estrogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

ramp up or turn down the gene like a switch

A

progesterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

In Serum Carrier Proteins, what are the Sex Hormone-Binding globulin/ Androgen Binding Protein

A

Testosterone
DHT
Estradiol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

In Serum Carrier Proteins what are the Corticosteroid binding globulin

A

Progesterone
Cortisol
Corticosterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

In Serum Carrier Proteins what are the Albumin (4)

A

Estradiol
Testosterone
Progesterone
Estriol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Is albumin a free steroid

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What binds cell surface receptors

A

Non-steroid hormone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What are the 2 class of membrane bound receptor

A

Metabotropic
Ionotropic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

change receptor shape to allow metabolism

A

Metabotropic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

shape like ion channels, allows ion to flow through into the cell. Important tissue to move ion in and out by opening the membrane

A

Ionotropic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Large scale effect on cell function

A

metabotropic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

change membrane, polarization

A

Ionotropic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Affinity: how —- a ligand will stick to its receptor

A

well

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Why is affinity important in Receptor Specific Responses
different affinity, the bind will be different to the receptors
26
What is high affinity vs low affinity
High = sticks longer and activates better Low = sticks not long and does not activate better
27
What is the most important thing in Receptor Specific Responses
The concentration/dosages
28
GnRH: Released from: Class: Target: Action: increase ---- and ---- release
Hypothalamus Peptide anterior pituitary LH FSH
29
KISS: Released from: Class: Target: Action: increase/ decrease ---- release
Hypothalamus Peptide Hypothalamus GnRH
30
Why is GnRH Important
Major hormone in behavior
31
What is Kispeptin
controls timing to released puberty and controls the release of GnRH
32
Melatonin: Released from: Class: Target: Action: increase or decrease ---- release
pineal gland amine hypothalamus GnRH
33
What is the Hormone control of the Pineal gland
Melatonin
34
LH: Released from: Class: Target: Action: induces ---- promotes ---- formation increases luteal ----
Anterior Glycoprotein Ovary/testis Ovulation Luteal formation Luteal P4
35
FSH: Released from: Class: Target: Action: ---- development/maturation, increase ---- synthesis
Anterior Glycoprotein Ovary/testis follicular developement estrogen
36
Oxytocin: Released from: Class: Target: (3): ——- gland, ———gland, ——— Action: increases ---- motility, increases PGF2a, milk ejection
Posterior Peptide Uterus, Mammary gland, Accessory glands Uterine motility Increases PGF2a Milk ejection
37
Estradiol (E2): Released from: Class: Target: (3) ——-, ——- tract , ——— gland Action: (4) increase for all 4
follicle steroid hypothalamus, repro tract, mammary gland increase sexual behavior, increase GnRH production, increase uterine activity, mammary development
38
inhibin: Released from: Class: Target: Action:
follicle glycoprotein pituitary decrease FSH release
39
Progesterone (P4): Released from: Class: Target:(3) : ———, ——- endothelium/myometrium, ——— glands Action: ---- maintenance, decrease ---- behavior, decrease ----, decrease ---- activity, and lactation
corpus luteum steroid hypothalamus, uterine endothelium/myometrium, mammary gland pregnancy sexual GnRH uterine
40
Relaxin: Released from: Class: Target(3): Action: soften ---- and ----
Corpus Leuteum Protein Uterus Cervix Pelvis ligaments and cervix
41
testosterone (T): Released from: Class: Target(2): Action(5): spermatogenesis, increase ---- development, decrease ----, male sex behaviors, ---- maturation
Testis Steroid Reproductive tract Muscle muscle GnRH sperm
42
Estradiol: Released from: Class: Target (2): Action (5): spermatogenesis, increase ---- development, decrease ----, male sex behaviors, ---- maturation
Testis Steroid Brain and Repro tract muscle GnRH sperm
43
How to convert T to Estradiol
Aromatase
44
prostaglandin E2: Released from: Class: Target: Action (2): ---- production, regulate ---- tone
Uterus prostaglandin Ovary progestrone muscle
45
prostaglandin F2a: Released from: Class: Target(2): Action (2): ---- P4, uterine ----(ends pregnancy)
Uterus Prostaglandin Ovary Uterine myometrium Decrease progestrone contraction
46
Progesterone: Released from: Class: Target(3): Action (2):
Placenta Steroid Hypothalamus Uterine Mammary gland Pregnancy decrease sexual, GnRH, uterine activity
47
Chorionic Gonadotropin (CG): Released from: Class: Target: Action:
Placenta Glycoprotein Ovary maintain Progestrone
48
Placental Lactogen: Released from: Class: Target: Action: prepartum ---- development
Placenta Protein Mammary gland mammary
49
The endocrine system can be regulated at different levels. 3
The quantity of hormones Availability of hormones Sensitivity of the target tissue
50
What are the quantity of hormone (3)
Synthesis Release Elimination
51
What is the availability of hormone
Binding protein association
52
What is the sensitivity of the target tissue
regulate sensitivity of cell by changing receptor up or down regulation
53
Example of regulating sensitivity of cell
Ridlin increases neuroactivity but decreases sensitivity
54
What are the 2 types of control mechanisms for hormones?
positive and negative feedback
55
(-) feedback: functions to maintain ______. (ex: ______steroids in males)
homeostasis Gonadal
56
(+) feedback: creates altered physiological states by amplifiying pushes the variable from the set point to achieve specific physiological purpose (ex: ________ in female)
GnRH
57
Pulsatility: the way that most ---- hormones are secreted. The quantity in circulation is a product of ----, ----, ----. Changes in the Frequency/amplitude dictate the ---- of hormone
reproductive Frequency Amplitude Elimination function
58
What is the patterns of hormone secretion
Basal Episodic Sustained
59
Patterns of hormone Secretion: Basal: ---- hormone levels Episodic: having an episode of ---- release (a spike in a graph) Sustained: steady ---- and plateau
Baseline High Incline
60
Half life practical implications (3)
detection Dosage Withdrawl period
61
Glucuronidation or steroid metabolism: Located in ----. A ---- molecule is attached to a steroid. This molecule is is very hydro----. This makes the steroid water ---- for destruction. Then it is taken to ----
liver Glucose hydrophilic kidney
62
Glycoprotein Excretion: Small glycoproteins are removed directly by the ----. Filtration rate is dependent on ---- state. Intact hormones can be detected in ----
Kidney glycosylation state urine
63

ANSC 333 (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions