Exam 1 Study Guide Flashcards

(40 cards)

0
Q

What type of study uses measures that include: counts, proportions, rates, survival

A

Descriptive Study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

What type of study describes or characterizes the distribution of a disease in a specified population during a defined time period?

A

Descriptive Study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The following strengths are characteristic of what kind of study:

  • describes frequency and pattern of health related states or events
  • provides critical information for research, prevention and policy
A

Descriptive Study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The following challenges are characteristic of what type of study?
- impossible to monitor everything ( cost, time)

A

Descriptive Study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What type of study relates two or more population based measures to examine possible correlates between exposure and disease occurrence?

A

Ecological Study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What type of study measures exposure and disease independently at the population level. ( not in the same individual). Correlation does not prove causation.

A

Ecological Studies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The following strengths are characteristic of what type of study?
- describes potentially useful correlations that may warrant further study (hypothesis generating)

A

Ecological Study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The following challenges are characteristic of what type of study?

  • information not at the level of the individual
  • ecological fallacy
  • cannot demonstrate cause and effect
A

Ecological Study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What type of study:

  • surveys a defined population, usually within a short period of time
  • study sample is usually identified without consideration of the distribution of exposure or outcome of interest
  • examines distribution of disease and exposure as ascertained in the cross sectional survey
A

Cross Sectional Study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

The following strengths are characteristic of what type of study?

  • can stimulate prevalence of disease and/or exposure as well as cross classifications. Estimate can be useful in healthcare planning and delivery
  • can be suggestive of risk factors for disease that may warrant further study
A

Cross Sectional Study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

The following challenges are characteristic of what kind of study?
- temporal relation between exposure and outcome is not known, thus can not demonstrate cause and effect

A

Cross Sectional Study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What type of study is characteristic of the following?

  • experimental design: intervention is under the control of the investigator
  • participants randomized to receive experimental intervention vs standard intervention (or placebo)
  • monitor out come of interest over time
A

Randomized Controlled Trials

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What type of study is characteristic of the following?

  • experimental design similar to randomized clinical trial
  • subjects are often non-diseased members of a target population and the intervention is often aimed at disease prevention
  • unit of randomization is the community/group level (school,hospital,sports team) rather than individual level
A

Community Trials

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What type of study is well suited for studying rare diseases?

A

Case Control Study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

In what type of study are participants selected on the basis of thier disease status?

A

Case Control Study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What type of study is often used to identify factors that may contribute to a medical condition by comparing subjects who have that condition/disease (the “cases”) with patients who do not have the condition/disease but are otherwise similar (the “controls”).

A

Case Control Study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

The following strengths are characteristic of what kind of study?

  • timeliness
  • relatively low cost (compared to cohort study)
  • ability to study rare outcomes
A

Case Control Study

17
Q

The following challenges are characteristic of what type of study?

  • no direct measure of disease risk
  • retrospective ascertainment of exposure
  • selection of appropriate controls
  • restricted to study of single out come
A

Case Control Study

18
Q

What type of study is an analysis of risk factors and follows a group of people who do not have the disease, and uses correlations to determine the absolute risk of subject contraction.

19
Q

The following strengths are characteristic of what type of study?

  • document exposure prior to disease occurrence
  • direct measure of disease rates and risk
  • opportunities to assess multiple outcomes
20
Q

The following challenges are characteristic of what type of study?

  • long time frame (usually)
  • cost (expensive)
  • loss to follow up
  • inefficient for uncommon diseases
21
Q

When an investigator documents but does not manipulate the exposure of interest the overall design is said to be what?

A

Observational

22
Q

When the investigator manipulates or assigns the exposure of interest the overall design is said to be what?

A

Experimental/Interventional

23
Q

What type of studies are considered to be observational?

A
Descriptive
Ecological
Cross Sectional
Case Control
Cohort
24
What type of studies are considered to be experimental/ interventional?
Randomized Controlled Trial Field Trials Community Trials
25
What term describes new cases of disease diagnosed in a defined population during a specified time period? Measures include counts, percentages, rates
Incidence
26
What term describes the total number of cases (new and existing) of disease present on a defined population during a specified time period or at a specific point in time? Measures include counts, percentages
Prevalence
27
What term describes deaths due to the disease of interest occurring in a defined population during a specified time period? Measures include counts, percentages, rates
Mortality
28
What are two strategies to minimize bias?
Randomization | Blinding
29
Participants assigned to study groups at random is know as what?
Randomization
30
The following purposes are characteristic of what? - diminish the opportunity for "confounding" by equalizing the effects of extraneous variables between/among the study groups - diminish the opportunity for selection bias
Randomization
31
Assignment of study group conducted without the knowledge of study participants and/or investigators is know as what?
Blinding
32
The following purposes are characteristic of what? - minimize bias in ascertainment of outcomes - minimize differential attrition of participants
Blinding
33
What scenario occurs when either study subjects or investigators do not know intervention status?
Single Blind
34
What scenario occurs when neither study subjects nor investigators know intervention status?
Double Blind
35
What is the primary measure of association that is derived from cohort studies?
Risk Ratio (RR) also known as Relative Risk
36
What is the primary measure of association that is derived from randomized controlled trials?
Risk Ratio (RR) also known as Relative Risk
37
What is the primary measure of association that is derived from case control studies?
Odds Ratio (OR) also known as Estimate of Relative Risk
38
Among those with the exposure of interest what term expresses the proportion of the disease that is due to exposure and could be prevented if the exposure was eliminated?
Attributable Risk Percent (RR - 1)/RR multiplied by 100 (OR - 1)/OR multiplied by 100 Or Risk in exposed - Risk in unexposed/Risk in exposed
39
In the entire population what term expresses the proportion of the disease that is due to the exposure and could be prevented if the exposure was eliminated?
Population Attributable Risk Percent E(RR-1)/[1+ E(RR-1)] E(OR-1)/[1+ E(OR-1)] E = % exposed in total population Or Risk in entire population - Risk in unexposed/Risk in entire population