Exam 1 Study Guide (Modules 1-3) Flashcards

(42 cards)

1
Q

5 main points in the Surgeon’s General’s call to actions on obesity

A

2001
1) Promote the recognition of overweight and obesity as major public health problems.

2) Assist Americans in balancing healthful eating with
regular physical activity to achieve and maintain a
healthy or healthier body weight.

3) Identify effective and culturally appropriate
interventions to prevent and treat overweight and
obesity.

4) Encourage environmental changes that help
prevent overweight and obesity.

5) Develop and enhance public-private partnerships
to help implement this vision

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2
Q

Categories for BMI

A

Class 1 (low-risk) obesity = 30.0-34.9 BMI

Class 2 (moderate-risk) obesity = 35.0-39.9 BMI

Class 3 (high-risk) obesity = 40.0-49.9 BMI

Super obesity = equal to or greater than 50.0 BMI

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3
Q

How to calculate BMI

A

A person’s weight in kilograms divided by the square of height in meters
BMI= kg/(m)^2 or
BMI= kg/(m)(m)

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4
Q

Top 4 disease risk by overweight and obese

A

Cardiovascular disease
Hypertension (high blood pressure)
Type 2 diabetes
Chronic inflammation
Stroke

Disease risk increases beginning at BMIs of 25-29.9and further at BMI of 30. Risk has to do with adiposity vs lean tissue mass

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5
Q

Limitations of BMI and why its important

A

1) BMI fails to distinguish between fat and muscle mass
2) Ethnicity (some body fat percentages at ethnicities are normal compared to others)
3) Older adults tend to have more body fat than younger adults for an equivalent BMI
4) Women have greater amounts of total body fat than men with an equivalent BMI

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6
Q

Metabolic Syndrome

A

Group of conditions that together increase risk of cardiovascular disease, type 2 diabetes, and stroke

Five risks that make up metabolic syndrome:
1) High waist size/circumference (greater than 102 cm in men and 88 cm in women)
2) High triglycerides (greater than 1.7mmol/L)
3) Low HDL-Cholesterol (less than 1.03 mmol/L in men and less than 1.29 mmol/L in women)
4) High blood pressure (greater than 120mmHg or 85 mmHg)
5) High glucose (greater than 5.6 mmol/L)
If a person has 3/5 of these, they will most likely be diagnosed with metabolic syndrome

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7
Q

Framing Principles

A

Individualized frame: Defining a problem in individualized terms limits governmental responsibility; Individual causing the problem
System frame: Systemic frames invite governmental action; System is causing the problem

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8
Q

5 Social Determinants of Health

A

1) Education access and quality
2) Economic stability
3) Social and community context
4) Neighborhood and build environment
5) Health care access and quality

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9
Q

3 Theoretical Perspectives in Sociology and What Sociology Encompasses

A

1) Functionalist: Concerned with order, balance, and stability in society, with social structure and the ways in which society’s parts fit together. Essentially, functionalists focus on impact, on consequences, regardless of intent
2) Conflict Theorist: Especially concerned with the ways in which the benefits of human social arrangements are distributed. See society as constantly changing, and they see conflict as the primary engine of change
3) Social Interactionist: Focus more on the micro-sociological level - on interactions between individuals and among small groups, and they ask what meanings are conveyed and how

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10
Q

5 layers of socio-ecological framework

A

Smallest
Individual: Knowledge, skills, and attitude
Interpersonal: Family, friends, and social networks
Organizational: Organizations, social institutions
Community: Relationships among organizations
Public policy: National, state, local laws
Largest

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11
Q

Nutrient dense

A

High levels of nutrients per serving (vitamins, minerals, etc)
Ex: Vegetables, fruits, whole grains, seafood, eggs, unsalted nuts, seeds

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12
Q

Energy dense

A

More calories per serving
Ex: Yogurt, cookies, donuts, fast food

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13
Q

Main points of the “Poverty and Obesity related to energy” article

A

1) Highest rates of obesity occur among population groups with the highest poverty rates/the least education
2) There is an inverse relation between energy density and energy cost, such that energy-dense foods composed of refined grains, added sugars, or fats may represent the lowest-cost option for the consumer
3) The high energy density and palatability of sweets and fats are associated with higher energy intakes
4) Poverty and food insecurity are associated with lower food expenditures, low fruit and vegetable consumption, and lower-quality diets

Poverty and obesity relationship is due to the low cost of energy dense foods and the high palatability of sugar and fat. More Americans become overweight and obese while consuming more added sugars and fats and spending a lower percentage of their disposable income on food

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14
Q

Bioenergenetics

A

The flow of energy through biological (living) systems, including human beings

Study of how energy is transferred in cells, tissues, and organism in which the body utilizes and transfers energy from carbohydrates, proteins, and fats

Process is through cellular metabolism

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15
Q

Intermediary Energy Metabolism

A

The intracellular process that convert food material into specific products (metabolites) by the action of enzymes with a net production of energy

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16
Q

Energy Balance

A

The relationship between energy intake (food calories taken into body) and energy output (calories being utilized for daily energy requirement)

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17
Q

Anabolism

A

Cells utilize smaller molecules and free energy to rebuild larger molecules requires energy
Needed for organism to maintain, grow, and store molecules
Ex: Formation of polypeptides from amino acids, glucose forming glycogen, and fatty acids forming triglycerides

18
Q

Catabolism

A

Breaking down large complex molecules into smaller units
Releases energy
Needed for organism to perform activities
Ex: Proteins broken down into amino acids, carbohydrates into glucose, and triglycerides into fatty acids

19
Q

ATP and its relation to energy

A

Energy is obtained through high-energy bond/source called ATP (adenosine triphosphate). Fuels the work of all body cells

Carbohydrates: Glycolysis (glucose and ATP make pyruvate and more ATP) and cellular respiration (pyruvate from glycolysis make ethanol and lactic acid)
Protein: Amino acids create pyruvate to create glucose
Fat: Dehydrogenase; C18FA-CoA + acetyl CoA = ATP

20
Q

Energy balance in relation to calories

A

Based on thermodynamics
energy cannot be destroyed and thus can only be gained, lost, or stored by the organism
Energy balance is the state achieved when the energy intake equals energy expenditure
Energy (initial) + Energy (expenditure) = 0

21
Q

Thermodynamics Laws 1 and 2

A

1) Law of conservation of energy: Energy can be changed from one form to another, but it cannot be created or destroyed. Focus is on transfer of energy from one form to another
2) Law of entropy: Entropy (disorder) must increase if a reaction is to be spontaneous. Applies to metabolism, and therefore, to bioenergetics

22
Q

Decreasing entropy

A

Human consumes food and decreases entropy via anabolic metabolism
Protein, carbohydrates, lipids, vitamins, minerals, water, and other food components

23
Q

Increasing entropy

A

Human generates wastes and increases entropy via catabolic metabolism
Carbon dioxide, water, and other components of breath, urine, feces, and sweat

24
Q

Difference in caloric balances

A

Isocaloric balance: Weight maintained; Energy in = Energy out
Negative caloric balance: Weight loss; Energy in < Energy out; High hunger index
Positive caloric balance: Weight gain; Energy in > Energy out; High satiety index

Cycle:
Eat food, digest food, absorb food nutrients, transport nutrients, store food calories, burn calories, eat food

25
BMR
Basal Metabolic Rate One of the three ways calories are expended Energy is expended through basal metabolic rate 60-75% of the time Energy metabolism that occurs after waking in the morning, at least 12 hours after last meal; Includes energy for functions that sustain life: Breathing, Heart beat, Brain, Liver, Kidneys
26
TEF
Thermic effect of food One of the three ways calories are expended Energy is expended through TEF 5-10% of the time Process of burning calories as you digest, absorb, transport, store, and metabolize food; Diet can have a mild influence (A little higher for protein)
27
TEE
Total energy expenditure TEE = BMR * Physical activity + TEF
28
NEAT
Non-Exercise Activity Thermogenesis Calories burned through daily physical activities outside of structured exercise Ex: Household chores, walking, fidgeting, posture, daily activities Physical activity expends energy 15-30% of the time
29
How to calculate BMR
BMR for women = 665.1 + (9.563*weight in kg) + (1.85*height in cm) - (4.676*age) BMR for men = 66.5 + (13.75 * weight in kg) + (5.003 * height in cm) - (6.775 * age) Activity factor Sedentary: 1.2 Lightly active: 1.375 Moderately active: 1.55 Very active: 1.725 Extra active: 1.9
30
Nature vs. Nurture
Nature (genetics) vs. Nurture (environment or environmental conditioning)
31
Genetics
The branch of discipline of biology that seeks to understand and explain genes, heredity, and variation in living things
32
Epigenetics
The study of how our behaviors and environment can cause changes that affect the way our genes work Epigenetic changes are reversible and do not change DNA sequence Epigenetic changes affect gene expression to turn genes "on" and "off"
33
DNA
Deoxyribonucleic acid carries genetic information in body's cells Made of chemicals A, T, C, and G that are repeated over and over in pairs, and they are held together by hydrogen bonds
34
Components of genetic material
Genes: Long chunks of DNA; Coded instructions for making everything the body needs, especially proteins Cell Genome: DNA contained within the complete set of chromosomes Chromosome: Contain DNA Polypeptides DNA: Carries genetic information in body's cells DNA, RNA, Genes, Plasmids, Chromosomes, Mitochondrial DNA
35
Proteins
Chains of chemical building blocks called amino acids. Proteins form the basis of what the body does, such as digestion, making energy, and growing
36
Chromosomes
Genes packaged in bundles. Humans have 23 pairs of chromosomes (total of 46). 1 pair is the sex chromosomes, and the other 22 are autosomal chromosomes
37
Human genome project
Complete copy of the entire set of human gene instructions Human Genome Project (2003) identified all the human genes in DNA and stored the information in databases so all researches everywhere could use it
38
Application of inherited genetics
Genes are either dominate, recessive and are inherited from small levels of taste genes to our perspective on obesity TAS2R38 gene with TT alleles - taste bitterness TAS2R38 gene with tt alleles - cannot tase bitterness TAS2R38 gene with Tt alleles- can taste bitterness TAS2R38 gene is a dominant allele
39
3 ways genes can be expressed
1) DNA Methylation: Can modify gene expression by adding a chemical group to DNA. Blocking proteins that attach to the DNA to read the gene 2) Histone Modification: DNA wraps around protein called histone and surround the gene in which makes it difficult for the gene to be read 3) Non-coding RNA: Coding RNA is used to make proteins. Non-coding RNA aids in control of gene expression by attaching to coding RNA, along with certain proteins, to break down the coding RNA so it cannot be used to make proteins. Non-coding RNA may also recruit proteins to modify histones to turn genes "on" and "off"
40
3 types of genetic obesity in humans
Syndromic: Obesity caused by chromosomal rearrangements (Prader-Willi syndrome, WAGR syndrome, Cohen syndrome, etc) Monogenic: Obesity inherited. Examples include mutations in the leptin signaling pathway Polycenic: Accounting for 60% of inherited obesity. These mutations are specific to genes (CYP27A1, TFAP2B, PARK2, UCP2 - which code for uncoupling proteins in skeletal and brown adipose tissue). Often other associated genes result in appetite control and energy balance
41
Twins studies relation to genetic obesity
Body weight differences in identical twins (monozygotic; single egg fertilized by single sperm and then split into two) must be due to environmental influences. However, there is evidence to suggest a genetic basis for obesity
42
How are overweight and obesity defined?
Defined by Body Mass Index (BMI). Moderately correlated with more direct measures of body fat. Strongly correlated with various metabolic and disease outcomes