Exam Flashcards
(118 cards)
Medications for age related changes
-decreased body water
-decreased lean tissue
-increased body fat
-decreased albumin
-decreased liver and renal function
-decreased GFR (decreases renal clearance)
-decreased hepatic blood flow
-receptor sensitivity
risk factors for medications
-pathologic processes
-functional impairments
-polypharmacy
-inadequate monitoring
-financial barriers
-insufficient recognition of adverse effects
-inappropriate prescribing
-communication barriers
-lack of information
Changes That Affect the Action of Medications in the Body
-Age-related changes in body composition (i.e., decreased body water and lean tissue and increased body fat, decreased albumin, decreased liver and renal function).
-Medications that are distributed primarily in body water or lean body mass may reach higher serum concentrations and their effects may be more intense.
-Serum concentration of highly fat-soluble substances can increase, so the immediate therapeutic effects are diminished, but the overall effects are prolonged or erratic
STOPP/START
evidence-based screening tool of older persons’ prescriptions
Communication barriers
Older adults reluctant to challenge or question
Fear of appearing ignorant
Hearing and vision impairments
Attitude of impatience on part of health professionals
Language barriers
prescribing cascade
adverse drug reaction mistaken as new medical condition
Medications and Nutrients
-Changes in the gastrointestinal tract can delay or diminish the absorption of medications.
-Medication interactions are likely to occur if the following medications are taken with food: biphosphonates, carbidopa/levodopa (Sinemet), ciproflocacin (Cipro), digoxin (Lanoxin), furosemide (Lasix), glipizide (Glocotrol), levothyroxixin (Synthroid), metformin (Glucophage), metoprolol (Lopressor) and warfarin
medications and alcohol
-Central nervous system depression
-Health care providers often do not accurately assess an older adult’s alcohol consumption.
-Alcohol can alter the therapeutic action of medications and increase the potential for adverse effect
-Over-the-counter preparations may have alcohol as an ingredient.
More susceptible to interactions between alcohol and medications
medications and nicotine
-Associated with tobacco smoking, smokeless tobacco and other nicotine-based products
-Affects therapeutic action of the medication
-Smokers may require higher doses of a medication
-Dosages of medications may need adjustment.
Functional Consequences Associated with Medications in Older Adults
-Altered Therapeutic Effects
-medications need to be monitored more closely in older adults, especially initially and when there is any change in the person’s medical status or treatment regimen
“start low and go slow.”
-Increased Potential for Adverse Effects
-Decline in function, an increased risk for falls and fractures, an increased number of visits for health care services, admission to a hospital or prolongation of a hospital stay
-Anticholinergic Adverse Effects
-Altered Mental Status
-Delirium
Common types of medications with anticholinergic properties
antidepressants, antihistamines, antiparkinson agents, antipsychotics, cardiovascular agents, gastrointestinal agents and urinary antispasmodics
Antipsychotics in People With Dementia
Extrapyramidal side effects, anticholinergic side effects = risks of orthostatic hypotension and falls
tardive dyskinesia
Rhythmic and involuntary movements of the trunk, extremities, jaw, lips, mouth or tongue.
The earliest signs are usually fine, wormlike movements of the tongue.
Other early signs include chewing, grimacing, lip smacking, jaw clenching, eye blinking and side-to-side jaw movements.
Manifestations can begin as early as 3 to 6 months after initiation of antipsychotic medications, and they usually persist even after the causative agent is discontinued.
It is considered an adverse effect of dopamine receptor-blocking agents and serotonin-norepinephrine reuptake inhibitors (i.e., certain antipsychotics and antidepressants)
Tardive dyskinesia deserves special attention with regard to older adults because advanced age correlates with both an earlier onset and increased severity of tardive dyskinesia.
drug induced Parkinsonism
Parkinson-like manifestations.
Manifestations can be reversed if the offending drug is stopped
The condition is often misdiagnosed as Parkinson disease and treated inappropriately with an antiparkinson medication.
Main causative drugs identified in studies include antipsychotics, calcium-channel antagonists, valproic acid and antiepileptic agents
Factors that Increase the Risk for Adverse Medication Effects
Increased numbers of medications
Frailty
Malnourishment or dehydration
Multiple illnesses
An illness that interferes with cardiac, renal or hepatic function
Cognitive impairment
History of medication allergies or adverse effects
Recent change in health or functional status
Medications in any of the following categories: anticoagulant/antiplatelet, antidiabetics, NSAIDs, central nervous system drugs
Barriers to nursing assessment of medications
time limitations
complex medication regimens
lack of a trusting relationship
Scope of medication assessment
All medications and other bioactive substances used
Individual’s understanding of medications
Allergies and adverse reactions
Perception and preferences
Cultural factors influencing medication use
Sources of health care
Observing patterns of medications used
-Ask to see all medications used or have them bring all medication to appointment (both prescription and over-the-counter medications).
-Direct observation of medication containers
Linking the medication assessment to the overall assessment
-Past and present medications: Help identify health issues.
-Identify clues to problems or complaints.
-Assess for residual adverse effects.
-Expected versus actual outcomes of medication interventions
-Functional ability to take medications
-Assessment of the living environment
-Risks for nonadherence
Nursing Interventions to Promote Safe and Effective Medication Management
Medication reconciliation
Teaching about medications and herbs
Addressing factors that affect adherence
Decreasing the number of medications
nociceptive pain
-Physiologic process leads to perception of noxious stimulus as painful
-Way of signaling that something is wrong.
-Caused by tissue damage
-Often localized to the area where damage or injury has occurred.
-Four processes: transduction, transmission, perception and modulation
neuropathic pain
-Caused from damage or dysfunction of nervous system.
-Unlike nociceptive pain, which is typically caused by tissue damage , neuropathic pain is often due to abnormalities in the nerves themselves.
-Abnormal processing of sensory stimuli by central or peripheral nervous system
-Can occur in the absence of immediate tissue damage or inflammation
acute pain
-Sharp, immediate pain from injury to tissue
-Time limited and responsive to analgesic
persistent pain
-lasts longer than 3 to 6 months or beyond the expected time of healing
-Continues for prolonged period; may or may not be associated with a recognizable disease process