exam 2 Flashcards
(351 cards)
what is hypertension
- common and manageable chronic condition
- major risk factor for other severe medical disorders
- leads to increased risk of premature morbidity and morality
- > 130/>80
risk factors for HTN
- cigarette smoking
- obesity
- physical inactivity
- excessive alcohol use
- diet
- stress
- dyslipidemia
- diabetes
- microalbuminuria or GFR <60mL/min
- age
- family hx of premature CVD in males below 55 and females younger than 65
BP =
CO x PVR
- mechanisms that involve increased CO, increased PVR, or both will overall increase BP
- anything that increases HR or circulating volume will increase BP
- anything that increases PVR, like angiotensin II will increase BP
increased sodium intake causes
increased sodium fluid retention increasing stroke volume and BP
renin-angiotensin-aldosterone system (RAAS) causes
- excess angiotensin II resulting in vasoconstriction and increased BP
- excess angiotensin also resulting in increased aldosterone
aldosterone causes
- sodium and water retention resulting in increased stroke volume and BP
- enhanced K+ secretion causing low K+
- low K+ increases vasoconstriction through closure of K+ channels
sympathetic nervous system causes
- vasoconstriction reuslting in increased peripheral vascular resistance and increased BP
- ## can increase HR
essential hypertension
- family hx
- african americans
- hyperlipidemia
- smoking
- older than 60 or postmenopausal
- excessive sodium and caffeine intake
- overweight/obesity
- physical inactivity
- excessive alcohol intake
- low K+, Ca+, or Mg
- excessive and continuous stress
secondary hypertension
- kidney disease
- primary aldosteronism
- pheocromocytoma
- cushing disease
- coarctation of aorta
- brain tumors
- encephalitis
- pregnancy
- drugs: estrogen, glucocorticoids, mineralocorticoids, sympathomimetics
out of office and office BP elevated =
sustained HTN
out of office high and office BP normal =
masked HTN
out of office BP normal and office BP high =
white coat HTN
out of office BP normal and office BP normal =
normal BP
elevated BP
120-29/<80 mmHg
stage 1 HTN
130-139/80-89 mmHg
stage 2 HTN
140+/90+ mmHg
hypertensive crisis
> 180/>120
hypertensive urgency
DBP >=120mmHg w/ no s/s of organ damage
hypertensive emergency
DBP >120mmHg w/ evidence of organ damage
renal findings if TOD present
- proteinuria
- elevated BUN and creatinine
- decreased eGFR
endocrine findings if TOD present
- elevated Na+
- elevated K+
- elevated TSH
metabolic findings if TOD present
- fasting blood glucose >100mg/dL
- LDL, triglycerides
- low HDL
other tests for TOD
- left ventricular hypertrophy
- low hematocrit
treatment for HTN
- based on severity
- goal: deccrease BP readings and minimize or prevent end-organ damage
- first step: life style changes
- second step: medications