final Flashcards
(250 cards)
pancreas hormones
- insulin
- glucagon
target cells of insulin
cells of body to lower blood glucose levels by moving insulin into cells
glucagon target cells
- liver and muscles
- promotes glycogenolysis by increasing blood glucose levels by conversion of glycogen to glucose
exocrine function
secretion of pancreatic juices into the small intestine that aid in digestion
endocrine function
blood glucose control by the islet cells; insulin (beta cells) and glucagon (alpha cells)
when blood glucose gets high…
the pancreas releases insulin to stimulate the liver to convert glucose into glycogen for storage to LOWER blood glucose levels
if blood glucose is too low…
glucagon causes liver to turn stored glycogen back into glucose and release it to INCREASE blood glucose levels
risk factors of diabetes
- age >30 years for type 2 and <30 years for type 1
- elevated HDL and triglyceride levels
- hx of gestational diabetes or delivery of baby >9lb
HTN - family hx of diabetes
- obesity
- previously impaired fasting glucose test
- african americans, hispanics, native americans, asians, pacific islanders
pre-diabetes
- impaired fasting glucose, impaired glucose tolerance
- warning for development to type 2 DM
fasting blood glucose pre-diabetes
100-125 mg/dL
a1c prediabetic
5.7-6.4%
oral glucose tolerance test prediabetic
140-199mg/dL
type I DM
- autoimmune disorder causing beta cells of pancreas to be destroyed resulting in no insulin production
- children and young adults
- total insulin deficiency occurring within 1 year
- lifelong insulin therapy needed
- surgery induced diabetes
type II DM
- insulin resistance: body tissues do not respond to insulin’s action due to unresponsiveness or insufficient numbers of insulin receptors
- inadequate insulin secretion: cell of pancreas become fatigued and so insulin production is decreased
diagnosing diabetes
- fasting blood glucose >126
- A1C >6.5%
- oral glucose tolerance test >200mg/dL
- random glucose test >200mg/dL
testing must be repeated before diagnosis
clinical manifestations of diabetes
- polyuria (increased urination)
- polydipsia (increased thirst)
- polyphagia (increased hunger)
- glucosuria
- fatigue
- unexplained weight loss (type I)
medical management of diabetes
maintenance of glycemic levels and prevention of complications
type I medical management
- glucose monitoring
- insulin
- diet
- patient education
- disease management
type II medical management
- glucose monitoring
- medications
- diet
- exercise
- weight loss
- patient education
- disease management
assessing glycemic control
- self monitoring w/ finger stick (before meals and at bed time)
- continuous glucose monitor (skin impant or close loop system, insulin pump)
- Hgb A1C (2x/year q3 months if targets haven’t been met)
diet for diabetics
- weight, meds, activity, and comorbidities should be taken into account
- consistency in times for meals
- carb counting
- incorporate diet individually
exercise for diabetics
- exercise lowers glucose levels and encourage weight loss as well as many other health benefits
- dietary adjustments
- if glucose >250 and urinary ketones are present, do NOT exercise until levels are normal
- try to exercise at same time each day
- insulin shouldn’t be injected in area that will be worked out
- monitor levels before, during, and after workout
insulin therapy
- regular insulin
- lispro
- glargine
- determir
regular insulin
use of this insullin increases change of hypoglycemia if give 3-4x/day due to action overlap