EXAM 2 Flashcards
(60 cards)
What are predictors of drug use, misuse, abuse, and dependence?
Intrapersonal and extrapersonal
What are extrapersonal predictors for drug use, misuse, abuse, and dependence?
It is neurological and cognition
What are predictors for extrapersonal drug use, misuse, abuse, and dependence?
social groups and large social/physical environment
What is the chicken and the egg?
Does a variable lead to later drug use or addictive behavior (is it a predictor), or does it stem from drug use or addictive behavior (outcome). A (antecdents), B (behaviors), C (consequences)
What are genes?
Genetic variations, genetic polymorphisms and allele associations lead to
differences in metabolic processes, which may lead to addiction
What are brain structures?
Brain variation or structure/pathway communication may
lead to addiction
What are brain juices?
Neurotransmitters and neuropeptides
What is the genetic variance of drug abuse?
30% to 60% of the variation in drug abuse
What is the genetic variance of alcoholism among siblings?
rug abuse (e.g., Deak & Johnson, 2021; Facal et al., 2021—50% of alcoholism; twin studies; e.g., brother-brother, father-son; COGA Study
What is the amygdala?
emotional processing of sensory inputs; innervates VTA; conditioned incentives
What is the hypothalamus?
set-point, regulation functions; innervates VTA
What is the ventral tegmental area?
VTA (manufacture of DA)
What is medial forebrain bundle?
MFB) (carrier of DA)
What is the nucleus accumbens?
an endpoint of DA, sends information to motor areas)
What is the palladium?
connects movement-control regions
What is the hippocampus?
guidance of behavior from episodic inputs; long-
term memory
What is the anterior cingulate cortex?
executive processing, planning
What is the prefrontal cortex?
another endpoint of DA; Dorsolaeral PFC [working memory]
What are neurotransmitters?
They are associated with appetitive-motivated behaviors
What is the orbital frontal cortex?
(implicit cognition, emotion, motivation
What is the medial frontal cortex?
effort-based reward-related decision making
What is serotonin?
It is associated with emotion/pleasure maintenance and sleep processing
What is dopamine?
It is associated with novelty, pleasure, and reward
What do recreational drugs do to the brain and neurotransmitters?
They appear to increase DA turnover