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Flashcards in Exam 2 Deck (93)
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1

What is the site of synthesis of Calcitonin including type of cells

"C" cells of the thyroid gland

2

Chemical class of calcitonin

PPP

3

2 primary functions of calcitonin

Decrease plasma calcium and decrease osteoclast cell synthesis and activity

4

3 secondary functions of calcitonin

Decrease digestion, plasma phosphorus, and plasma sodium

5

True of false calcitonin lowers phosphate in plasma

true

6

True or false calcitonin increases bone reabsorption

False, it inhibits it

7

Name two clinical uses for calcitonin

Osteoporosis and Paget's disease

8

What is osteoporosis

Bone mass and strength decreased

9

What is Paget's disease?

Disorder of the normal bone remodeling (example of old men talking about their hats not fitting because they're getting smarter)

10

True or false the bone that develops from Paget's disease is strong and normal

False, it is weak, abnormal and enlarged

11

What is the site of synthesis for Erythropoietin in adult

Kidney

12

What is the site of synthesis for Erythropoietin in a fetus

Liver

13

What is the chemical class of Erythropoietin

PPP

14

What is the function of Erythropoietin

Stimulate the development of RBC

15

Name 3 hormones that control the secretion of Erythropoietin

STH, Substance P, and Thyroxine

16

What is Erythropoietin EPO and what produces it

A hormone produced by the kidney

17

What does Erythropoietin EPO do?

promotes the formation of red blood cells by the bone marrow

18

What clinical treatment would Erythropoietin EPO be used for

Patients with amenia

19

What famous athlete used Erythropoietin EPO and why was it beneficial

Lance Armstrong, using the drug in a healthy body increases the RBC count and thus can increase an athletes VoMax

20

Name three things that can cause an increase in Erythropoietin

Performance enhancing drugs, heart attack or stroke, and thickening of the blood

21

True or false you would never prescribe Erythropoietin EPO to a patient with improperly functioning Kidneys

False, you WOULD prescribe Erythropoietin EPO (well...not you because you won't prescribe drugs)

22

Name the 2 sites of synthesis for Vitamin D

Liver and Kidney

23

Name the chemical class of vitamin D

Seco-steroid

24

What is the name of Vitamin D after hydroxylation in liver

25-hydroxcholecalciferol

25

What is the name of Vitamin D after hydroxylation in kidney

1, 25-Dihydroxycholecalciferol

26

What is the name of the form of Vitamin D in the kidney before it becomes hydroxylated again

1, 25-OH2D3

27

1-alpha-hydroxylase in the kidneys tightly regulates Vitamin D, what hormone controls 1-alpha-hydroxylase

Parathyroid hormone

28

What is the name of fully active form of vitamin D?

1, 25-Dihydroxycholecalciferol

29

Name the two primary functions of Vitamin D

Increase linear height, and increase plasma calcium

30

What is the secondary function of Vitamin D

Stimulate the integumentary system