Exam 2 Flashcards

(29 cards)

1
Q

zygote

A

from fertilization to 4 days old

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2
Q

blastula or blastocyst

A

hollow ball of cell forms around 4-5 days

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3
Q

gastrula

A

3 layered ball of cells forms 7-10 days

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4
Q

ectoderm

A

outer layer, forms skin and nervous systems

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5
Q

mesoderm

A

middle layer, forms muscle blood and bone

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6
Q

endoderm

A

inner layer, forms internal organs lungs liver intestines

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7
Q

neural plate

A

part of the back ectoderm that forms the neural tube by folding in on itself

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8
Q

neural tube

A

hollow tube of cells that eventually forms the spinal cord and brain

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9
Q

neural crest

A

these cells eventually migrate out and form the peripheral nerves

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10
Q

cell proliferation

A

the formation of two new cells from one cell

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11
Q

cell migration

A

the movement of cells from one place to another

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12
Q

cell differentiation and maturation

A

the process by which unspecialized stem cells or precursor cells take one their final specialized state

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13
Q

synaptogenesis

A

the formation of a functional synapse between an axon from a presynaptic neuron and the dendrites of a post synaptic neuron

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14
Q

myelination

A

the formation of myelin sheaths and neurons

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15
Q

The process of neural migration

A

starts around 8-9 weeks post conception and is complete 2-3 months before birth

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16
Q

two main types of migration

A

tangential and radial

17
Q

tangential

A

moving up/down or around

18
Q

radial

A

moving out from center

19
Q

Tangential migration of neural crest cells to form

A

Schwann cells and neurons in peripheral nerves

20
Q

Radial migration of cerebral cortical neurons to form

A

layers of the cerebral cortex

21
Q

The processes associated with neuronal maturation

A

chemical differentiation

morphological differentiation

22
Q

Chemical differentiation

A

hormones and other chemical signals activate master regulatory genes specific proteins done by birth

23
Q

master regulatory genes

A

genes that produce a protein that then turn on neuron

24
Q

morphological differentiation

A

cell taking on its adult form- dendrites and axons begin to form continues into childhood

25
The role of chemoattractants and adhesion molecules in process of axonal extension
1) secretion of chemoattractants from the target cell that guide the axon to them 2) cell adhesion molecules that then grasp the axon and adhere it to the target cell
26
Synaptogenesis process
starts during prenatal development and continues into late childhood
27
Creation of proper synaptic structure by cellular activites in both neurons
1) pre synaptic neuron needs to synthesize and store neurotransmitter vesicles 2) post synaptic neuron needs to form and insert neurotransmitter receptors into membrane
28
Neuronal cell death and synaptic pruning
post-synaptic cells secrete neurotrophins which promote survival of neurons. Neurons with a stronger connections get more neurotropic support those with weaker connections don't and eventually die. This 'scuplts' away neurons with weaker connections, leaving only ones with strong functional connections
29
Which regions of the brain undergo myelination first and which under go it last
Regions controlling basic sensory analysis and simple movement myelinate first, regions involved with decision making and impulse control myelinate last