Exam 2 Flashcards
(133 cards)
callous-unemotional traits
- lack of remorse or guilt
- lack of empathy
- unconcern about performance in important activities
- shallow or deficient affect
how are CU traits measured?
as set of traits, or diagnostically as a specifier of conduct disorder in the DSM
Conduct Disorder
clinical diagnosis characterized by: 1. aggression 2. destruction of property 3. deceitfulness 4. serious rule violations symptoms must occur before 18, unless in context of APD, before 16
ODD
pattern of negative, hostile, and defiant behavior
may have symptoms related to anger/irritability, may be argumentative/defiant/vindictive
ADHD
clinical diagnosis characterized by several inattentive or hyperactive-impulsive symptoms
comorbid with CD and ODD
adolescent limited CD
from Moffitt’s model; one pathway to CD where onset coincides with adolescence and is less likely to continue into adulthood; behavior may be exaggeration of normal adolescent rebellion process
life course persistent CD (5)
from Moffitt’s model; pathway where onset is early (6 years old) and continues into adulthood, where individuals are likely to have
- neuropsychological deficits
- cognitive deficits (IQ)
- temperament/personality risk factors
- genetic risk
- neural risk
ACC
neural area found to be important for flexible control of aversively motivated behavior; tracks outcomes of choices made in recent past and integrates reward info to allow adaptive modification of behavior
OFC
neural area found to be important for integrating signals and modulating activity of other brain regions. role in:
- representing affective value of reinforcers
- stimulus reinforcement learning
- decisionmaking
- executive function
amygdala
neural area found important for threat detection (“fear center”) and stimulus reinforcement learning, and esp as a salience motivation detector
ventral striatum
portion of striatum including 1. nucleus accumbens 2. olfactory tubercle 3. islands of Calleja reward center
dlPFC
neural area essential for executive functions (maintain/shift set, planning, response inhib, working memory, organization, reasoning, problem solving, abstract thinking)
MAOA
enzyme affecting NTs dopamine, NE, and 5HT
serotonin genes (5HTTLPR)
codes for serotonin transporter
COMT
modifying gene; role in modulating PFC dopamine levels, associated with subtypes of antisocial behavior
heritability
statistic used in genetics that estimated how much variation in a phenotypic trait in a population is due to genetic variation among individuals in that population
culpability (3)
culpable if cause a negative event act
- act was intentional
- act and consequences could have been controlled (agent knew likely consequences, was not coerced, and overcame hurdles to make event happen)
- person provided no excuse or justification for actions
mitigation
circumstances that may be considered by a court in determining culpability of a defendant or extent of damages to be awarded to a plaintiff
do not justify or excuse offense, but may reduce severity of charge
high MAOA + ___ leads to (2)
- maltreatment
2. proactive aggression and CU traits
low MAOA + ___ leads to
aggressive/impulsive behavior
pathway for low MAOA leading to aggression/impulsivity
+ maltreatment, leads to increased amygdala and decreased cortical response (increased availability of 5HT activates amygdala)
pathway for high MAOA leading to callous/proactive aggression
+ maltreatment, leads to decreased amygdala response (decreased availability of 5HT)
homozygous long allele for 5HTTLPR + ___ leads to…
+ low SES; high CU and narcissistic traits
homozygous short allele for 5HTTLPR + ___ leads to…
impulsivity