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Flashcards in Exam 2.2 Deck (97)
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1

What is the iceberg effect of measles

Essentially zero

2

How is measles spread

from person to person via respiratory droplets. Super contagious

3

What kind of virus causes measles and mumps

Paramyxovirus

4

What kind of genome does measles virus have

enveloped, (-)ssRNA

5

What kind of capsid does measles virus have

helical

6

How many measles virus serotypes are there

just 1

7

What kind of vaccine is the measles mumps and rubella vaccine (MMR)

attenuated

8

What factors increase death rate from measles infection

poverty that causes malnutrition

9

What percent of the population must be vaccinated against measles virus to have herd immunity

92-94% because it is so highly infectious

10

What is one unusual effect of a measles virus infection

It suppresses the immune system which allows for secondary infections

11

Is it possible to completely rid the world of measles, mumps and rubella viruses

Yes, because humans are the only reservoir for all three

12

What kind of genome does mumps virus have

(-)ssRNA, enveloped

13

How is mumps spread

from person to person via respiratory droplets

14

What tissue does measles virus initially infect

Lung epithelium and local lympathics

15

What tissue does mumps virus initially infect

Lung epithelium, and also potentially eyes and nose

16

After measles virus goes systemic, what tissue does it infect

Epi/endothelium, thus the characteristic measles rash

17

After mumps goes systemic, what tissue does it infect

Glands including salivary and testicular ducts, but especially the parotids

18

What is the most common permanent damage caused by mumps virus infection

Duct damage resulting in deafness or sterility

19

Who is especially at risk in a rubella infection

Baby has a 25% chance of severe birth defects if mom gets a primary rubella infection in the first trimester

20

What is the iceberg effect of mumps virus

25% of infected individuals don't show signs and symptoms

21

What type of virus is Rubella

togavirus

22

what kind of genome does rubella virus have

(+)ssRNA, enveloped

23

How is rubella virus spread

from person to person via respiratory droplets

24

What tissue does rubella initially infect

respiratory tract.

25

What kind of virus is Respiratory Syncytial Virus

Paramyxovirus

26

What kind of genome does RSV have

(-)ssRNA, enveloped

27

How is RSV spread

from person to person via respiratory droplets

28

What tissue does RSV initially infect

Lung epithelium

29

What is the course of development of RSV infection

75% individuals develop UIR, 25% develop LRI and of those 3-5% require hospitalization

30

Who is most at risk for complications from RSV infection

kids with cystic fibrosis often die from RSV