Exam 3

Question 1

Mutations in the APC gene lead to ___________. APC protein is part of a destruction complex which ___________.

Answer 1

Polyps, Inhibits Wnt/beta catenin signaling

Question 2

Curcumin is derived from black pepper and has been proven to prevent many types of cancer.

Answer 2

False

Question 3

The experimental arm of a clinical trial is testing a new treatment for breast cancer.
In the control arm patients receive?

Answer 3

The best, most established effective treatment

Question 4

The majority of sexually active people will be exposed to the HPV virus in their lifetime.

Answer 4

True

Question 5

Reactive oxygen species are?

Answer 5

Produced in the Mitochondria
Found in antioxidant skin creams

Question 6

Recent studies have documented an unexpected increase in colorectal cancer in American women over 60 years of age.

Answer 6

False

Question 7

Colon cancer forms when cells within benign ___________ accumulate ____________ which lead to cancer.

Answer 7

Polyps, Mutations

Question 8

In 2019 the CDC reported that fully protective herd immunity has been achieved for vaccination against HPV-related cancers in the United STATES

Answer 8

False

Question 9

The obesity rate in America is less than 25%.

Answer 9

False

Question 10

To date, studies have failed to link daily use of any vitamin or supplement with any increase in lifespan.

Answer 10

True

Question 11

Telomerase inhibitors are a common effective treatment for a variety of cancers.

Answer 11

False

Question 12

Immune Checkpoint inhibitors are ____________ which block/cover proteins over-expressed on the surface of _________ cells.

Answer 12

Antibodies, Cancer

Question 13

Certain bacteria are found in higher numbers in colorectal tumors as compared to adjacent normal tissue. What can you conclude from this observation?

Answer 13

there is a positive correlation between the bacteria and the cancer

Question 14

Gardasil/HPV vaccine contains a heat-inactivated version of the HPV virus.

Answer 14

False

Question 15

In clinical trials, the strongest evidence for an effect comes from?

Answer 15

Randomized control trials

Question 16

Data from ___________ which can detect ___________ shed from tumors suggest that early-onset colorectal cancer might have a unique mutational profile.

Answer 16

Liquid biospy, cell free DNA

Question 17

Countries with higher HPV vaccine acceptance have demonstrated a lower prevalence of oncogenic HPV subtypes in the unvaccinated population.

Answer 17

True

Question 18

Herd Immunity can protect the unvaccinated.

Answer 18

True

Question 19

Lower death rates from cervical cancer in developed countries are due to the availability of the Pap smear test.

Answer 19

True

Question 20

Obesity can lead to insulin intolerance. Insulin can act as a growth factor for certain cancers.

Answer 20

True