Exam 3 - Drug uses

Question 1

Bethanecol

Answer 1

Post op urinary rent ion, neurogenic ileus

Question 2

Cevimeline

Answer 2

Dry mouth and dry URT
After head and neck irradiation
Sjogren’s

Question 3

Pilocarpine

Answer 3

Miotic in glaucoma

Partial agonist - so less headache

Question 4

Edrophonium

Answer 4

Diagnose Myasthenia Gravis

Distinguish b/t myasthenic and cholinergic crisis

Question 5

Donepezil

Answer 5

Alzheimer’s (recall in alzheimer’s you loss cholinergic neurons; this drug will work until all neurons are lost)

Question 6

Neostigmine

Answer 6

Increase GI activity post op

Question 7

Pyridastigmine

Answer 7

Treatment myasthenia gravis

Question 8

Malathion

Answer 8

pediculus capitis

Question 9

Atropine

Answer 9

mydriatic

Question 10

Cyclopentolate

Answer 10

mydriatic

Question 11

Tropicamide

Answer 11

mydriatic

Question 12

Scopolamine

Answer 12

Decrease GI activity
“Antispasmodic”
IBS

Question 13

Oxybutinin

Answer 13

Tx incontincence

Question 14

Tolterodine

Answer 14

Tx incontinence

Question 15

Solifenacin

Answer 15

Tx incontinence

Has specificity for M3, so no action on heart

Question 16

Ipratropium

Answer 16

Causes bronchodilation

Question 17

Tiotropium

Answer 17

Like ipratropium
Causes bronchodilation
Lasts 24 hours

Question 18

Epinephrine

Answer 18

alpha 1, beta 1, and beta 2 activity
Bronchodilator
Used to inhibit antigen-induced histamine release

Question 19

Albuterol

Answer 19

Bronchodilator

Question 20

Metaproterenol

Answer 20

Bronchodilator

Question 21

Salmeterol

Answer 21

Bronchodilator

Question 22

Phenylephrine

Answer 22

Nasal decongestant
Mydriasis
Increases peripheral resistance (pressor effect)

Question 23

Pseudoephedrine

Answer 23

Nasal decongestant

Indirect agonist

Question 24

Oxymetazoline

Answer 24

Nasal decongestant

Relieves eye redness and itching

Question 25

Dopamine

Answer 25

Increases CO (pressor effect) Indirect agonist Has some B1 activity

Question 26

Dubutamine

Answer 26

``` Beta 1 Increases CO (pressor effect) ```

Question 27

Midodrine

Answer 27

``` alpha 1 agonist used for sympathetic deficiencies --postural hypotension --urinary incontinence --retrograde ejaculation ```

Question 28

Isoproterenol

Answer 28

Cardiac stimulant | In AV block, prevent LOC

Question 29

Tyramine

Answer 29

Indirect sympathomimetic found in cheese and sausage

Question 30

Propranolol

Answer 30

HTN - -acts on heart - -blocks renin release from JG cells

Question 31

Timolol

Answer 31

HTN? | no Na block

Question 32

Pindolol

Answer 32

Angina, HTN | Partial agonist, so less dec HR and BP

Question 33

Atenolol

Answer 33

Less effect on lungs | Excreted in kidney

Question 34

Metoprolol

Answer 34

Less effect on lungs Excreted via liver Especially good in asthma and in preventing CV problems

Question 35

Tamulosin

Answer 35

BPH

Question 36

Prasosin

Answer 36

HTN

Question 37

Terazosin

Answer 37

HTN

Question 38

Phentolamine

Answer 38

block necrosis by injected sympathomimetics

Question 39

Ergotamine

Answer 39

Moderate migraine

Question 40

Ergonovine

Answer 40

Constricts/stops bleeding of uterus post partem

Question 41

Veranicline

Answer 41

Decreases smoking/nicotine satisfaction | Counteracts craving

Question 42

Bupropion

Answer 42

Antidepressent | May block some of nicotine's effect

Question 43

Mecamylamine

Answer 43

Ganglionic blocker Blocks first w/o stimulating Ganglionic blockers --sometimes used in orthopedic surgery to dec BP and blood loss