Exam 3: Lecture 23 - Anesthetic Complications Flashcards

(40 cards)

1
Q

When do we automatically associate a death with anesthesia after surgery?

A

-Death that occurs within 48 hours in small animals, or up to 7 days in horses

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2
Q

In dogs, cats, & rabbits, about ___ % of postoperative deaths occur within 3 hours of the end of anesthesia

A

50%

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3
Q

In horses, ___% of complications occur in recovery and are neuromuscular or respiratory in nature

A

92%

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4
Q

What complications can occur days to weeks after anesthesia?

A

-Decreased renal or hepatic function

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5
Q

What are common complications that can occur during the peri-anesthetic period?

A

-The 4 H’s!
1. hypoventilation
2. Hypotension
3. Hypothermia
4. Hypoxemia

-CV
-Respiratory
-CNS
-Anesthetic depth
-Temperature regulation
-Dysphoric recovery
-Gastroesophageal Regurgitation (GER) & possible aspiration

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6
Q

What are uncommon side effects that can occur during the peri-anesthetic period?

A

-Metabolic
-Neuromuscular
-Post-anesthesia cortical blindness

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7
Q

___ is a common CV complication due to drugs, physical status of patient, other causes of vasodilation (e.g. anaphylaxis)

A

Hypotension (MAP < 60 mmHg or < 90 mmHg on Doppler)

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8
Q

How do we treat the CV complications that can occur during anesthesia?

A

-Decrease depth, consider fluid therapy, and vasopressor and/or positive inotrope

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9
Q

With hypotension, a severe decrease in ___ leads to decreased perfusion of optic nerve and kidneys

A

BP

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10
Q

How is hypertension defined?

A

MAP > 150 mmHg

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11
Q

What are CV complications associated with anesthesia?

A

-Hypotension
-Hypertension
-Hypovolemia due to hemorrhage
-Cardiac arrest
-Arrhythmias (consider treatment if BP is affected. Look for underlying cause)

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12
Q

How is hypoventilation defined?

A

-ETCO2 > 55 mmHg
-Most common complication, usually caused by anesthetic drugs and/or excessive anesthetic depth.
-Could be due to pre-existing co-morbidities (always check equipment!)
-Can lead to respiratory acidosis, hypoxemia, and increased intracranial pressure

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13
Q

What is the treatment for hypoventilation?

A

-Check depth and adjust if appropriate
-Provide IPPV
-Change position of patient if possible
-Check equipment

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14
Q

When would we see hypoxemia in anesthetized patient?

A

-Unlikely if intubated and on 100% O2, but can quickly become life-threatening
-SpO2 of 95% = PaO2 of 80 mmHg
-SpO2 of 90% = PaO2 of 60 mmHg
-Patient can be hypoxemic and not show cyanosis!

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15
Q

What is the treatment for hypoxemia?

A

-Check O2 flow rate for adequacy
-Check placement of ETT
-Check anesthesia machine & SpO2 probe
-Give IPPV
-Consider adding PEEP (stert w/ 2.5 cmH2O)
-Assess perfusion and support cardiac output
-Change position to sternal & discontinue anesthesia if no improvement with other interventions

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16
Q

What are the 5 causes of hypoxemia?

A
  1. Hypoventilation
  2. V/Q mismatch
  3. Decreased FiO2
  4. Right to left shunt
  5. Diffusion impairment
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17
Q

When does GER (gastro-esophageal reflux) occur during general anesthesia?

A

-When gastric contents pass into esophagus
-Can look like clear or brown fluid coming from nose or mouth

18
Q

Up to ____ % of dogs may experience GER during general anesthesia, but not often noticed

19
Q

Can you see GER in cats?

A

-Yes, up to 33% incidence reported

20
Q

What can GER lead to?

A

-Esophagitis, esophageal stricture formation, or aspiration pneumonia

21
Q

What are risk factors for GER?

A

-Pregnancy (later stage)
-Anesthetic drug protocol (e.g. morphine)
-Abdominal & orthopedic sx
-Breed (brachycephalic, large, or deep-chested dogs)
-Expected complication of endoscopy
-Pre-existing conditions (GI disease, megaesophagus, dysphagia, regurgitation)
-Length of preop fasting time & type of food (small meal of canned food 3 hrs prior may reduce incidence of GER)
-Prolonged duration of anesthesia
-Recumbency & changes in body position during anesthesia
-Older dogs

22
Q

How do we treat GER?

A

-Be sure ETT cuff has good seal, use pH strip to measure pH - treat if acidic or basic
-Esophagus suctioned & lavaged w/ warm water & bicarb using urinary catheter or double-lumen suction catheter, after regurgitation occurs & before patient recovers
-Sucralfate & H2-receptor antagonist can be considered
-Admin. metoclopramide by bolus & CRI at higher doses than commonly used reduced incidence
-Oral omeprazole 4 hours prior may reduce GER
-Maropitant (Cerenia_ does NOT prevent GER

23
Q

What are some metabolic complications of anesthesia?

A

-Hypoglycemia or hyperglycemia (glycemic control important for diabetic patients, monitor BG at reg. intervals & be prepared to treat)
-Acid-base disturbance (resp. acid-base disturbance discussed in blood gas analysis lecture)
-Electrolyte imbalance

24
Q

Treatment of hyperkalemia should be done

A

BEFORE anesthesia, even in an emergency case!

25
What are some neurological & musculoskeletal complications of anesthesia?
-Myopathy -Neuropathy -Prolonged or weak recovery -Myoclonus -Seizures -Post-anesthetic cortical blindness
26
How is myopathy caused in anesthetized patients?
-By ischemic muscle damage due to prolonged compression or inadequate padding and/or prolonged hypotension leading to under-perfusion of muscles
27
How is peripheral neuropathy caused in anesthetized patients?
-Stretching, compression, ischemia, metabolic derangement, & surgical resection
28
What is the treatment of myopathy & neuropathy?
-Prevention is better than treatment! -Treatment includes IVF for diuresis, analgesics, anti-inflammatory drugs, sedatives if needed, and vasodilators -Rehabilitation therapy is also beneficial
29
When can blindness after anesthesia be seen in cats?
-May be seen after dental cleanings, likely due to use of mouth gags leading to cerebral ischemia (maxillary artery blood flow compromised) -Could also happen due to severe hypotension and/or CPA
30
What are signs of dysphoria in recovery (aka "rough recovery")?
-Vocalization -Panting -Restlessness -Urination/defecation -Salivation **Emergence delirium**: -Thrashing, agitation, hyperexcitable -"Lights are on but nobody is home"
31
How is dysphoria treated in recovery?
1. Most commonly used = **dexmedetomidine** (could be continued as CRI if needed) 2. Commonly used = Acepromazine 3. If benzodiazipine is suspected as cause of dysphoria, the flumazenil may be considered 4. If severe dysphoria, consider propofol to "reset" recovery 5. Consider naloxone if opioid-induced dysphoria suspected (Use butorphanol instead if continued analgesia desired)
32
What are some examples of human error preventable complications?
-Leaving pop off valve closed -Intracarotid or perivascular injection -Walking away from patient & it falls off table -Tracheal tear from turning intubated patient attached to breathing system
33
What are some examples of drug preventable complications?
-Miscalculation, administration of wrong drug, incorrect dose, route, or reconstituted to incorrect concentration -Selected wrong drug for debilitated patient
34
What are some examples of equipment malfunction preventable complications?
-Sodasorb expired or channeling occurs -Oxygen tank runs out or O2 supply line disrupted -Misassmebly of machine or breathing system -Sticking of exhalation valves -> rebreathing CO2 -Hole in ETT cuff; kinking or obstruction of ETT
35
How are tracheal tears in cats caused?
-**Over-inflation of ETT cuff**, turning patient while connected to breathing system, stylet puncture, extubation with cuff inflated -Often seen in cats having dentals
36
What are the clinical signs of a tracheal tear in cats?
-Subcutaneous emphysema, dyspnea, respiratory stridor, pneumomediastinum +/- pneumothorax -Inspect ETT for blood at extubation -Signs develop hours to days after anesthesia - cat may stop eating, cough, and have a fever
37
How are tracheal tears in cats treated?
-Medical vs. surgical -O2 therapy, cage rest & sedatives -SQ emphysema may resolve in 1-6 weeks
38
How are tracheal tears in cats prevented?
-Use 3.5-4.5 mm ETT, add 0.5 mL air at a time with 3 cc syringe until pressure holds at 15-20 cm H2O -Disconnect patient when flipping -Deflate cuff for extubation
39
What are other possible surgery or anesthesia complications?
-Swollen feet and/or joint pain from being tied too tightly on surgery table -Corneal ulcers -Over administration of IVF -Epidural needle or local anesthetic being placed directly in the nerve
40
What should you do after an anesthetic complication?
-Hold M&M rounds afterwards to discuss complication(s) -Development of SOP to prevent or reduce future occurrences