Exam 3 Practice Questions

Question 1

Who observed the possible relationship between the cowpox virus and smallpox virus, developing the first vaccination?

Answer 1

Edward Jenner

Question 2

How are viruses grown in the laboratory?

Answer 2

in chick embryos

Question 3

What is a capsid, with regard to viral structure?

Answer 3

the protein layer enclosing viral genome

Question 4

What is the function of a glycoprotein in the viral envelope?

Answer 4

to allow a virus to attach to a host cell

Question 5

A capsid that has icosahedral symmetry results in a virus with a ___________ shape.

Answer 5

Spherical

Question 6

Which of the following is considered a spongiform encephalopathy?

Select one:

a. kuru
b. Chagas disease
c. parkinson’s disease
d. Huntington’s disease

Answer 6

Kuru

Question 7

A bacteriophage attaches to its host cell during which phase of replication?

Select one:

a. Adsorption
b. Penetration
c. Maturation
d. Release

Answer 7

Adsorption

Question 8

When viruses remain in a cell for a prolonged period of time, this is referred to as a _______________ infection.

Answer 8

Persistent

Question 9

What portion of an enveloped virus binds to the host cell?

Answer 9

Glycoproteins

Question 10

Which type of RNA virus has a nucleic acid composition that can immediately serve as mRNA?

Answer 10

positive strand RNA viruses

Question 11

Retroviruses produce double stranded DNA from RNA. What name is given to the double stranded DNA molecule?

Answer 11

Proviral DNA

Question 12

Bacteriophage DNA is injected into the host cell during which phase of replication?

Select one:

a. Adsorption
b. Penetration
c. Maturation
d. Release

Answer 12

Penetration

Question 13

New viral assembly occurs during which phase of replication?

Select one:

a. Adsorption
b. Penetration
c. Maturation
d. Release

Answer 13

Maturation

Question 14

What enzyme is produced to allow viral release from the host bacterial cell?

Select one:

a. Lysozyme
b. Catalase
c. Perioxidase
d. Amylase

Answer 14

Lysozyme

Question 15

Following replication, how does a naked virus typically exit the cell?

Answer 15

by lysis

Question 16

Viral transformation may lead to:

Answer 16

cancer

Question 17

What is the name of the virus that causes smallpox?

Answer 17

variola

Question 18

About how many cases of smallpox occurred globally in 2015?

Answer 18

None

Question 19

Small flesh colored bumps are characteristic of which pox virus?

Answer 19

molluscum contagiosum

Question 20

Which pox virus is used to vaccinate for smallpox?

Answer 20

vaccinia

Question 21

Which poxvirus typically causes lesions on the hands and fingers?

Answer 21

orf

Question 22

What is the most common route of transmission of CMV?

Answer 22

sexual contact

Question 23

In AIDS patients CMV can cause ______________.

Answer 23

retinitis

Question 24

What are the two routes of transmission for the varicella zoster virus?

Answer 24

direct contact with vesicle fluid

respiratory secretions

Question 25

What is the site of latency for the VZV virus?

Answer 25

neurons

Question 26

Which of the following conditions is characterized by a rash in a single dermatome?

Answer 26

shingles (zoster)

Question 27

Infections due to HSV-1 are typically:

Answer 27

the oral cavity

Question 28

Infections due to HSV 2 are typically:

Answer 28

genital infections

Question 29

The lesions known as herpetic whitlow are frequently observed on:

Answer 29

the fingers

Question 30

Who contracts herpes gladiatorum?

Answer 30

wrestlers

Question 31

What is the site of latency for the Epstein-Barr virus?

Answer 31

B lymphocytes

Question 32

An overactive immune response to EBV results in which pathology?

Answer 32

mononucleosis

Question 33

Lack of immune response to EBV results in which pathology?

Answer 33

lymphoma

Question 34

What is the mode of transmission of EBV?

Answer 34

oral secretions

Question 35

Roseola is due to infection with:

Answer 35

HHV 6

Question 36

A child with a fever that persists for 3 days develops a rash that does not itch. What is the likely diagnosis?

Answer 36

roseola

Question 37

HHV 8 is responsible for:

Answer 37

Kaposi's sarcoma

Question 38

Which of the following is a common way to contract a human papillomavirus infection? Select one: a. sexual contact b. fecal- oral transmission c. respiratory transmission d. injection drug use

Answer 38

sexual contact

Question 39

Some strains of HPV can transform cells leading to _______________.

Answer 39

cervical cancer

Question 40

Common warts seen on the hands or fingers are typically the result of HPV ____________________.

Answer 40

on contaminated articles like towels

Question 41

Viruses known as JC and BK are which type of viruses?

Answer 41

polyomavirus

Question 42

Fifth disease, also sometimes called "slapped cheek" disease is caused by ________________.

Answer 42

parvovirus

Question 43

What is the function of the N (neuroaminidase) glycoprotein spike?

Answer 43

to aid in viral exit from the host cell

Question 44

What is the function of the H (hemagglutinin) glycoprotein spike?

Answer 44

to allow the virus to attach to the host cell

Question 45

What is the mode of transmission for the rubeola (measles) virus?

Answer 45

respiratory

Question 46

On of the hallmarks of measles is the whitish patches inside the oral cavity, what are these mucosal patches called?

Answer 46

Koplick's spots

Question 47

Encephalitis is an occasional complication of which of the following viruses, occurring in approximately 1 in 1000 cases?

Answer 47

rubeola virus

Question 48

Parainfluenza viruses are responsible for which of the following conditions?

Answer 48

croup

Question 49

Mumps is an infection of the ________________

Answer 49

salivary glands

Question 50

What is the mode of transmission for the mumps virus?

Answer 50

respiratory

Question 51

Orchitis is a somewhat common complication of mumps. What is orchitis?

Answer 51

testicular swelling

Question 52

What is the mode of transmission for the rubella virus?

Answer 52

respiratory

Question 53

A baby born with hearing loss, mental retardation and heart defects may be suffering from:

Answer 53

congenital rubella

Question 54

A 31 years old male patient who is HIV + complains of fever and loss of peripheral vision. A blood specimen is submitted to detect viral antigen. Which virus is likely causing these symptoms?

Answer 54

CMV (cytomegalovirus) Can cause retinitis in the eye of up to 15% of AIDS patients

Question 55

A 72 year old woman complains of a burning, painful rash on her chest. A physical exam reveals a vesicular rash limited to the dermatomal area of T7-T8. What is the likely diagnosis?

Answer 55

HZV Latent varicella virus in neurons is reactivated

Question 56

A 22 year old sexually active man complains of warts on his penis. The man is tested fro HPV, in addition to his female partner. What might she be at risk for developing is she is positive?

Answer 56

Cervical cancer

Question 57

A 19 year old college student presents with fever, very painful sore throat and headache. Physical exam reveals enlarged lymph nodes and a slightly enlarged spleen. What virus might be responsible for this?

Answer 57

Epstein Barr virus Becomes latent in B cells

Question 58

At a preferment evaluation, a 31 year old pregnant woman reports pain on urination and a burning itching sensation in the genital area. What virus is most likely causing these symptoms?

Answer 58

HSV-2 (could also be HSV 1 but unlikely) She should not have a vaginal delivery

Question 59

A 16 year old male present with tenderness and swelling of the left testis. He also reports difficulty swallowing and on exam, his salivary glands are enlarged. What virus is causing his symptoms?

Answer 59

Mumps

Question 60

A 20 year old college student presents with fever, cough and conjunctivitis. Physical exam reveals pale patches in the oral mucosa and a rash on her face, spreading to her trunk. She is unvaccinated due to personal beliefs, What is her likely diagnosis?

Answer 60

Measles (disease) which is cause by infection with rubeola (virus)