Exam 3 slides 1 Flashcards
Laterized
-One hemisphere is more involved
-Language is laterized
Epilepsy
-Characterized by seizures
-“Cluster” of disorders
-When severe requires surgery
Seizures
-Excessive or synchronous brain activity
Grand mal seizures
-Most severe
-Generalized tonic clonic seizures
Generalized and tonic clonic meaning
Generalized: Seizure spreads to both hemispheres, loss of consciousness
Tonic Clonic: Involves muscle contractions
Electricorticography
-Determines seizure origin
Wada test
- inject a sedative into one of the arteries
- Have a patient speak continuously
- This gradually moves into the hemisphere on that side
- As it reaches the hemisphere, is their speech impaired?
- If so, don’t do surgery on that side
Brocas aphasia
-“Non fluent”, unable to produce speech
-Can comprehend language fine
Wernickes aphasia
-“Fluent”, able to produce speech
-Speech makes little sense, cant comprehend language
Focal resection
-If seizures have a clear origin or “seizure focus” it can be removed
-These patients are often studied with the lesion method
Corpus Callosotomy
-Cutting the corpus callosum (nerve fibers that connect the right and left hemisphere
Split brain patients
-Have undergone a corpus callosotomy
-Appear fine, need to probe more carefully to detect deficits
Split brain experiment-oddities
-Asked patient to look at objects selected from both hands
-Left hemisphere will make up a story to explain what the other hand grabbed
-Possible psychological defense mechanism
Left vs right brain functions
Left: Analytic thought, Logic, Language, Science and math
Right: Holistic thought, Intuition, Creativity, Art and music
Neural correlates of consciousness NCC
-What is the basis of consciousness?
-Most unknown question in neuroscience
-Connectivity
Neuropil
All of the tissue of the brain
Local connectivity
-The brain is constantly active
-Electromagnetic fields always flowing through neuropil
Local field potentials LFP
-Name for the electromagnetic fields
-Flow through the brain and affect neurons
Ephaptic coupling
When LFPs influence neurons
Neurodynamics
Study of brain interactions