Exam 4 Flashcards
(69 cards)
What are modifiable systemic risk factors?
Type 2 diabetes
Tobacco use
What are non-modifiable systemic risk factors?
Type 1 diabetes
Genetic influences
Periodontal health declines as what climbs?
Blood sugar
What are the oral complications of poorly controlled diabetes?
o Reduced salivary flow
o Abscess formation
o Cheilosis
o Burning mouth/tongue
o Altered hyperinflammatory response to infection
o Imbalance bone destruction and repair
uncontrolled/poorly controlled diabetes on periodontium
occurs when glucose binds to biomolecules, transforming them into harmful, tissue-destructive molecules
Glycation
o Inextricably links collagen fibers together
o AGE-modified collagen can occur in blood vessel walls
o Implicated in diabetes-related complications such as Neuropathy, retinopathy, & nephropathy
Cross-Linking of AGEs
What does AGE-RAGE interaction contribute to?
o Increased inflammation
o Insulin resistance
o Impaired tissue repair
Beneficial because it physiologically prepares body to respond to fight-or-flight situation
Essential adaptive instinct for survival
Acute stress
o Maladaptive; impedes homeostasis
o Mediated by cortisol
Chronic stress
What can chronic stress effects manifest as?
Anxiety
Depression
Impaired cognition
Altered self-esteem
pyogenic granuloma
Pregnancy benign tumor
Localized overgrowth of tissue
o Natural condition in fourth to sixth decades
o Estrogen levels fluctuate
o Many drastic physical and behavioral changes
o Estrogen declines can lead to systemic bone loss
Menopause on periodontium
A reduction in bone mass making the woman more prone to bone fractures
Osteoporosis
A condition in which there is a lower-than-average bone density but not necessarily an increase in risk or incidence of bone fracture
Osteopenia
Cluster of related metabolic disturbances that tend to occur together and initiate proinflammatory state
Metabolic syndrome
o Having three or more components significantly associated with higher risk of periodontitis
o May influence progression of periodontitis by contributing to chronic low-grade inflammation
Metabolic syndrome
o Increase risk for certain cancers and infections
o Has profound effect on cellular immunity
o Delays healing following tooth extraction
HIV/AIDS
o Gingival manifestation of HIV infection
o 2 to 3mm marginal band of intense erythema in free gingiva
o Exaggerated intensity
Linear gingival erythema
Safe to perform periodontal therapy if patient has undetectable viral level and high CD4+ count
HIV infected
Disorder characterized by presence of abnormally few numbers of neutrophils in blood
Neutropenia
o Increases susceptibility to infection and periodontal disease
o Treat acute periodontal exacerbations by removal of local causative factors
o Patients considered immunocompromised
Neutropenia
What are down syndrome people more at risk for?
Congenital heart defect
Infection
Respiratory problems
GI abnormalities
Childhood leukemia
o Rapid cancer of blood cells, usually white blood cells
o Usually benign in bone marrow
Leukemia