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Flashcards in Exam Deck (44):
1

Management of basal cell papilloma/seborrhoeic keratosis

Cryotherapy

2

Why are keratoacanthomas often excised?

Difficulty to distinguish between a SCC

3

Difference between a papule and a nodule?

Papule is less than 0.5cm

(both are solid raised lesions)

4

Staph infection around/within a hair follicle

Furnuncle

5

Functions of skin:

a) Langerhans cells
b) Merkel cells

a) Antigen presenting cells of the skin
b) light touch mechanoreceptors

6

Four layers of epidermis from deep --> superficial

Basal
Prickle
Granular
Stratum corneum

7

Pearly lesion with a rolled edge and telangiectasia

Basal cell carcinoma

8

BCC treatment options? (4)

Excision
Moh's micrographic surgery
Cryotherapy
Imiquimod

9

What pattern of sun exposure broadly predisposes to a) BCC b) SCC?

a) intense, intermittent e.g. severe episodes of sunburn
b) chronic sun exposure e.g. an outside occupation like a farmer

10

Squamous cell carcinoma in situ is also known as...

Bowen's disease

11

SCC precursor lesions? (2)

Actinic keratoses
Bowen's disease

12

Patch of malignant melanocytes proliferating radially along the dermo-epidermal junction

Lentigo maligna

13

Commonest melanoma type?

Superficial spreading

14

Melanoma subtypes:
a) invasive growth from outset
b) seen on sole/palm/subungual
c) radially prolferating along the DEJ
d) diffuse blue/black patch on lower back/buttocks of a child

a) nodular
b) acral
d) lentigo maligna
d) Mongolian blue spot (congenital)

15

ABCDE criteria for assessing melanoctyic lesions?

Asymmetry
Border (irregular)
Colour (heterogenous)
Diameter (>6mm)
Evolution over time

16

Blistering skin disease:

IgG deposition in a "chicken-wire" pattern around cells within the epidermis

Pemphigus

17

Blistering skin disease:

linear IgG deposition along the basement membrane

Pemphigoid

18

Blistering skin disease:

IgA deposition in clusters around the dermal papillae

Dermatitis herpetiformis

19

Mutations in which gene predispose to atopic eczema?

Filaggrin

20

Management principles of eczema? (3)

Antimicrobial soap substitutes
Liberal use of emollients
Topical steroids

21

Episodic eczema of the palms/soles, with bullae formation

Acute pompholyx eczema

22

Management of rosacea? (3)

Trigger avoidance
Topical metronidazole
Antibiotics/roaccutane

23

What treatment should be avoided in rosacea and why?

Topical steroids- cause widespread facial erythema and rebound flares

24

Management of acne? (4)

Benozyl peroxide
Antibiotics
Isotretinoin
COCP/Dianette

25

Signs of chronic venous hypertension? (5)

Stasis eczema
Hyperpigmentation
Lipodermatosclerosis
Varicose veins
Atrophie blanche

26

Painful, palpable purpuric lesion --> punched out ulcer?

Vasculitic ulcer

27

Mainstay of venous ulcer treatment?

Compression bandaging

28

Violaceous plaques --> atrophy to become brown/yellow, seen in diabetics

Necrobiosis lipoidica

29

Treatment of impetigo?

Fusidic acid if localized, flucloxacillin if generalized

30

Causative agent of cat-scratch disease?

Bartonella

31

Treatment of localized fungal disease?

Terbinafine, miconazole, clotrimazole (antifungals)

32

Risk of systemic antifungal treatment?

Hepatotoxicity

33

Treatment of viral warts? (4)

Salicylic acid ("wart paint") for 12 weeks
Cryotherapy
Podophyllotoxin
Imiquimod

34

Fluid-filled blister on finger due to direct inoculation of herpes virus?

Herpetic whitlow

35

Causative agent of molloscum contagiosum?

Pox virus

36

Multiple purplish patches caused by herpes virus 8

Kaposi sarcoma

37

Child with fever, severe sore throat and vesicular rash over pharynx? Causative agent?

herpangina from coxasckie virus

38

HPV subtypes:
a) common warts
b) genital warts

a) 1, 2, 4
b) 6, 11, 16 and 18

39

Sites favoured by psoriasis?

Extensor surfaces of knees and elbows

40

Nail involvement in psoriasis? (3)

Pitting, oncholysis, subungual hyperkeratosis

41

Management of psoriasis?

Vitamin D analogues
Steroids for flares
Narrowband UVB
Coal tar preparations
Dithranol

42

Eruption of itchy reddish-purple papules on wrist, back and genitalia + lacy white streaks in oral mucosa

Lichen planus

43

Short flu-like illness --> single/few oval patches --> sudden eruption all over body

Pityriasis rosea

44

Patches of discolouration caused by Malassezia yeast

Pityriasis versicolor