Flashcards in Non-melanoma skin cancer Deck (14):
Which skin tumour is clasically described as pearly, with a rolled edge and telangiectasia?
Basal cell carcinoma
Complications of basal cell carcinoma (2)
Very rarely metastasize but can cause local destruction
Where do BCCs typically occur?
Mainly the face, but also other sun-exposed areas
What questions should be asked in the history to assess risk factors for skin cancer? (8)
Occupation (and sun exposure)?
Typical response to sun (i.e. Fitzpatrick scale)?
Any previous serious episodes of sunburn (with blistering)?
History of sunbed use?
Significant time spent abroad?
Family history of skin tumours?
Personal history of skin problems/tumours?
Any immunosuppressive medication?
Treatment options for basal cell carcinoma (5)
Excision with a margin of 4mm
Moh's micrographic surgery
Curettage and cautery (for small superficial lesions)
Cryotherapy for small low risk lesions
Topical Imiquimod or 5'FU
Clinical variants of basal cell carcinoma? (4)
What pattern of sun exposure broadly predisposes to a) BCC b) SCC?
a) intense, intermittent e.g. severe episodes of sunburn
b) chronic sun exposure e.g. an outside occupation like a farmer
What is Bowen's disease?
Squamous cell carcinoma in situ (i.e. confined to the epidermis)
Red and scaly patches, typically waxing and waning over time, often seen on scalp and other sun-exposed areas
Why are actinic keratoses and Bowen's disease usually removed?
Precursor lesion to squamous cell carcinoma
What is a common variant of Bowen's disease and where are lesions seen in this condition?
Erythroplasia of Queyrat- on the penis
Why is SCC more serious than BCC?
As well as being locally invasive it may metastasize to regional lymph nodes
Presentation of SCC?
Variable, but typically presents as a non-healing ulcer with hard edges, which may bleed/itch. Local lymphadenopathy if metastatic