Exam # ANTITUBERCULARS, ANTIFUNGALS,ANTIVIRALS

Question 1

Rifampin (Rifadin®) - antibuercular

Answer 1

Could be given in multiple drug regimen
o Firstlineofdrugs
o More effective and less toxic than second line o Combinationtherapy
 Minimum of 3 to 5 drugs
 Initial phase
 Last 2 months  Continuation phase
 Next 4 to 7 month

Question 2

Rifampin (Rifadin®) - antibuercular Side Effects/Adverse Reactions?

Answer 2

Headaches, dizziness, confusion
 GI distress
 Peripheral neuropathy
Ocular toxicity, ototoxicity, nephrotoxicity, hepatotoxicity
 Thrombocytopenia
 Respiratory depression
 Rifampin turns body fluids orange
 Tears, urine, sweat, sputum, vaginal secretions
 Contact lenses may be permanently discolored

Question 3

Isoniazid (INH) - antibuercular General Info?

Answer 3

1 pill a day 
Route
 Oral
 IM
o Inhibits bacterial cell wall synthesis

Question 4

Isoniazid (INH) - antibuercular Side effects/adverse reactions

Answer 4

Dry mouth, GI distress, constipation
 Blurred vision, photosensitivity, tinnitus
 Drowsiness, dizziness, peripheral neuropathy
 Psychotic behavior, tremor, seizures
 Hyperglycemia
 Hepatotoxicity
 Thrombocytopenia
 Agranulocytosis

Question 5

Isoniazid (INH) - antibuercular Assessment

Answer 5

Obtain general medical history from the patient

 Assess for hearing changes if drug regimen includes streptomycin

Question 6

Isoniazid (INH) - antibuercular Planning?

Answer 6

The patients sputum test for acid fast bacilli will be negative 2-3 months after
prescribed antitubercular therapy

Question 7

Isoniazid (INH) - antibuercular Interventions?

Answer 7

Administer INH 1 hours before or 3 hours after meals
 Give vitamin B6 (pyridoxine) as prescribed with INH to prevent peripheral
neuropathy

Question 8

Vitamin B6 (Pyridoxine)?

Answer 8

Given with antitubercular medications which can cause  Hyperglycemia
 Hyperkalemia
 Hypophosphatemia  Hypocalcemia
o GIVE WITH INH (ISONIAZID) to prevent peripheral neuropathy

Question 9

Mycostatin (nystatin) – ANtifungal

Answer 9

It is a polyene

Question 10

Nystatin(Myocstatin) Action?

Answer 10

Binds to sterols causing loss of intracellular potassium and other cell contents

Question 11

Nystatin(Mycostatin) side Effects?

Answer 11

Skin irritation, rash, pruritus • GI distress

• Hyperglycemia, tachycardia • Angioedema, bronchospasm • Stevens-Johnson syndrome

Question 12

Nursing Process antifungals: assessment?

Answer 12

◦ Assess patient’s hepatic and renal function tests.

Question 13

Nursing Process: Antifungals: Diagnoses?

Answer 13

Knowledge, Deficient related to the treatment regimen.

Question 14

Nursing Process: Antifungals: Planning?

Answer 14

The patient’s fungal infection will be resolved without life-threatening adverse reactions.

Question 15

Nursing Process: Antifungals: Interventions?

Answer 15

Advise the patient to take drugs as prescribed. ➢ Advise the patient not to consume alcohol.
➢ Encourage the patient to report side effects.