Exam Review Pharm

Question 1

Any deviation from the normal rhythm of the heart

Answer 1

An arrhythmia

Question 2

Abnormal cardiac electrophysiological function is how what drug works?

Answer 2

Antiarrhythmics

Question 3

Class I drugs

Answer 3

Sodium channel blockers

Question 4

Sodium channel blockers exert their actions on the ?

Answer 4

Sodium (fast) channels

Question 5

Class II drugs

Answer 5

B-adrengeric blockers

Question 6

B-adrenergic blockers work by blocking:

Answer 6

Sympathetic nervous system stimulation of the heart

Question 7

Class III drugs

Answer 7

Potassium channel blockers

Question 8

Potassium channel blockers increase the?

Answer 8

Action potential duration by prolonging repolarization in phase 3

Question 9

Class IV drugs

Answer 9

Calcium channel blockers

Question 10

Calcium channel blockers work by:

Answer 10

Inhibiting the calcium channel

Question 11

Loop diuretics act primarily along the?

Answer 11

Ascending limb of the loop of henle

Question 12

Loop diuretics are used to manage edema associated with

Answer 12

Heart failure and hepatic or renal disease

Question 13

Loop diuretics are used to control

Answer 13

Hypertension

Question 14

Mannitol is a(n)

Answer 14

Osmotic diuretic

Question 15

Mannitol works along the:

Answer 15

Entire nephron

Question 16

Mannitols major sites of action is:

Answer 16

Proximal tubule and descending limb of the loop of henle

Question 17

Mannitol can be used to treat:

Answer 17

Cerebral edema

Question 18

Spironolactone and triamterene are used to treat:

Answer 18

Hyperaldosteronism and hypotension

Question 19

Chlorthalidone and hydrochlorothiazide are used in the treatment of:

Answer 19

Hypertension

Question 20

The therapeutic effects of ACE inhibitors and ARBs in the treatment of HF are related to:

Answer 20

Their potent vasodilating properties

Question 21

B-blockers prevent _________ __________ actions on the heart

Answer 21

Catecholamine-mediated

Question 22

Reduces HR, delays atrioventricular node conduction, reduces myocardial contractility and decreases myocardial automaticity

Answer 22

B-blockers

Question 23

Used in the severe stages of HF to decrease edema

Answer 23

Aldosterone antagonists

Question 24

Milrinone

Answer 24

Positive inotropic response and vasodilation

Question 26

Slows the heart and improves cardiac efficiency

Answer 26

Digoxin

Question 27

Diuretics Beta blockers Nitrates ACE inhibitors ARBS CCBs Alpha blockers All treat:

Answer 27

Hypertension

Question 28

Decreasing volumes of plasma and extracellular fluid, which results in decreased preload:

Answer 28

Primary effect of diuretics

Question 29

These drugs work by blocking a critical enzyme system responsible for production of angiotensin II

Answer 29

ACE inhibitors

Question 30

ACE inhibitors and ARBS are more effective in:

Answer 30

White population rather than black population

Question 31

Block sodium channels on peripheral vessels

Answer 31

DHP ccbs

Question 32

Triglycerides are stored in

Answer 32

Adipose tissue

Question 33

HMG-CoA reductase inhibitors Bile acid sequestrants Niacin (vitiman B3) Fibrates All can be used to treat:

Answer 33

Dyslipidemia

Question 34

Bind bile and prevent the resorption of bile acids from the small intestine

Answer 34

Bile acid sequestrants

Question 35

Effective in lowering lipid levels

Answer 35

Niacin

Question 36

Primarily effect triglyceride levels

Answer 36

Fibric acid derivatives

Question 37

Nitrates B-blockers CCbs All used to treat:

Answer 37

Angina pectoris

Question 38

Primary mechanism of nitrates

Answer 38

Vasodilation

Question 39

Drugs that prevent the formation of a clot

Answer 39

Anticoagulants

Question 40

Prevents clot formation

Answer 40

Antiplatelet

Question 41

Preventing the lysis of fibrin, promoting clot formation

Answer 41

Antiffibrinolytic

Question 42

Antianginal drugs help decrease the workload of the heart and reduce angina by?

Answer 42

Reducing the heart rate

Question 43

Beta blockers help treat stable angina by:

Answer 43

Reducing myocardial oxygen demand by reducing heart rate

Question 44

Nitrate therapy treats acute angina by:

Answer 44

Dilates coronary peripheral arteries more than coronary arteries

Question 45

Used to decrease the frequency and severity of exertional angina

Answer 45

Metoprolol

Question 46

Antihypertensive that has hyperkalemia as a potential side effect:

Answer 46

Spironolactone

Question 47

Diuretic used as a first line for treating hypertension

Answer 47

Hydrochlorothiazide

Question 48

An action of digoxin

Answer 48

Slows the heart rate

Question 49

Blocks the enzyme responsible for LDL-receptor breakdown

Answer 49

PCSK9 inhibitors

Question 50

Will stop a crucial step in the pathway of cholesterol synthesis

Answer 50

Rosuvastatin

Question 51

Decrease the slope of phase 0, depolarization, in myocytes

Answer 51

Sodium channel blockers

Question 52

Non-DHPs treat arrhythmias by:

Answer 52

Inhibiting nodal cell calcium channels, they reduce heart rate

Question 53

Propranolol is class?

Answer 53

Class II agent

Question 54

Disopyramide is class?

Answer 54

Class IA agent

Question 55

Amiodarone is class?

Answer 55

Class III agent

Question 56

Propafenone is class?

Answer 56

Class IC agent

Question 57

Verapamil is class?

Answer 57

Class IV agent

Question 58

Lidocaine is class?

Answer 58

Class IB agent

Question 59

Drugs that end in “pril”

Answer 59

ACE inhibiotrs

Question 60

Drugs that end in “lol”

Answer 60

Beta-blockers

Question 61

Blocks intestinal absorption of LDL

Answer 61

Ezetimibe

Question 62

reduces hepatic synthesis of LDL

Answer 62

HMG CoA reductase inhibitors

Question 63

Increase clearance of very low density lipoprotein VLDL

Answer 63

Fibric acid derivatives

Question 64

Promote intestinal clearance of cholesterol

Answer 64

Bile acid sequestrants

Question 65

Angina is a symptom of:

Answer 65

Ischemic heart

Question 66

Used to treat variant angina?

Answer 66

Nifedipine

Question 67

You should avoid _________________ with diltiazem

Answer 67

Grapefruit juice

Question 68

Used to treat symptoms of acute angina

Answer 68

Isosorbide dinitrate

Question 69

Drug used to treat supraventricular arrhythmias

Answer 69

Dilitiazem

Question 70

Arrhythmia that typically occurs because of scar tissues from an MI

Answer 70

Ventricular tachycardia

Question 71

Primary management of ventricular arrhythmias

Answer 71

Amiodarone

Question 72

Hydrochlorothiazide prescribed with furosemide in heart failure, it can cause

Answer 72

Hypokalemia

Question 73

Digoxin should be administer alone with what other drugs when used for treating heart failure

Answer 73

ACE inhibitors

Question 74

The effect on the heart when cardiac glycosides are used

Answer 74

Positive inotropic effect, increasing the force of contraction

Question 75

First line treatment of hypertension when coronary artery disease is present and ACE inhibitors are not tolerated

Answer 75

Olmesartan

Question 76

First like treatment of hypertension in patients with angina

Answer 76

Atenolol

Question 77

Drug that can cause dehydration and hypokalemia

Answer 77

Furosemide

Question 78

A drug associated with a characteristic cough side effect

Answer 78

Quinapril

Question 79

An orally administered anticoagulant used to prevent pulmonary embolism, thrombotic and embolic stroke

Answer 79

Warfarin

Question 80

Routes used to administer heparin and LMWH

Answer 80

IV and subcutaneous

Question 81

Thrombolytic drugs help dissolve clots by

Answer 81

Increasing the digestion of fibrin

Question 82

CCBs are used in the treatment of stable and unstable angina True/false

Answer 82

False