Exam Three Flashcards
(146 cards)
Tx for anorexia
ii. Behavior modification
iii. Therapy
iv. SSRIs, but may increase SI in adolescents
v. Meds with some success:
1. Fluoxetine (prozac)
2. Olanzapine (Zyprexa)
Tx for bulimia
i. SSRIs, but may increase SI in adolescents
ii. Meds with some success:
1. Fluoxetine (prozac)
2. Amitriptyline (elavil)
iii. Behavior modification
iv. Therapy
Tx for BED
i. Therapy
ii. Lisdextroamphetamine (Vyvanse)
iii. Meds for anxiety and depression as well
Alcohol use disorder
Pre-alcoholic phase
- Alcohol is used to relieve the everyday stress
2. Tolerance develops and amount required to achieve desired effects steadily increases
Alcohol use disorder
Early alcoholic phase
- Begins with blackouts
- Alcohol stops being a source of pleasure/relief and becomes a drug that is required
- Feels enormous guilt and becomes defensive
Alcohol use disorder
Crucial phase
- Addiction is clearly evident
- Binge drinking is common
- Anger and aggression
- Individual may lose job, marriage, family, friends, and self-respect
Alcohol use disorder
Chronic phase
- Emotional and physical disintegration
a. Profound helplessness and self pity
b. Psychosis - Unmanaged withdrawal can lead to hallucinations, tremors, convulsions, agitation, and panic
- Depression and SI aren’t uncommon
- For long term heavy drinkers, withdrawal can be fatal
Effects of alcohol on the body:
Peripheral neuropathy
Reversible with abstinence from alcohol and restoration of nutritional deficiencies
- Peripheral nerve damage
- Pain
- Burning
- Tingling
- Prickly sensation of extremities
Effects of alcohol on the body:
Alcohol myopathy
- Acute: muscle pain, swelling, and weakness; red tinge to urine; rapid rise in muscle enzymes in blood
- Chronic: gradual wasting and weakness in skeletal muscles
Effects of alcohol on the body:
Wernicke-Korsakoff syndrome
- Severe thiamine deficiency
- Encephalopathy: paralysis of ocular muscles, diplopia, ataxia, somnolence, stupor
- Psychosis: confusion, loss of recent memory, confabulation
Effects of alcohol on the body:
Alcoholic cardiomyopathy
- Accumulation of lipids in the myocardial cells, resulting in enlargement and a weakened condition; CHF; arrhythmia
Effects of alcohol on the body:
Leukopenia
- Function, production, and movement of WBCs impaired in chronic alcoholics
- At high risk for infectious diseases
Effects of alcohol on the body:
Pancreatitis
- Acute: 1-2 days after alcohol binge; constant, severe epigastric pain, N/V, abdominal distension
- Chronic: leads to pancreatic insufficiency; steatorrhea, malnutrition, weight loss, DM
Effects of alcohol on the body:
Hepatitis
- Enlarged and tender liver, N/V, lethargy, anorexia, elevated WBC, fever, jaundice
- Severe cases: ascites and weight loss
Effects of alcohol on the body:
Cirrhosis
- N/V, anorexia, abdominal pain, jaundice, edema, anemia, blood coagulation abnormalities
- Complications: portal HTN, ascites, esophageal varices, hepatic encephalopathy
Alcohol withdrawal timeline
- Anxiety, insomnia, nausea, and abdominal pain - 8 hours
- High BP, increased body temp - 1-3 days
- Hallucinations, fever, seizures, and agitation - 1 or more weeks
Meds for alcohol withdrawal
i. Benzos
ii. Anticonvulsants
iii. Multivitamin therapy
iv. Thiamine
Meds for maintaining abstinence from alcohol
i. Disulfiram (antabuse)
ii. Naltrexone (reVia)
iii. Acamprosate (Campral)
iv. SSRIs
Sedative-hypnotics
Drug types
Barbiturates
Non-barbiturates
anti-anxiety
club drugs
Sedative-hypnotics
Effects on the body
- Sleep and dreaming
- Respiratory depression
- Cardiovascular effects
- Hepatic effects
- Body temp
Sedative-hypnotics
Intoxication
- Effects range from disinhibition and aggressiveness to coma and death (with increasing doses of drug)
Sedative-hypnotics
Withdrawal
- Onset depends on half life of drug
2. Severe withdrawal from CNS depressants can be life threatening
Opioids
Types
- Opioids of natural origin
- Opioid derivatives
- Synthetic opiate-like drugs
Opioids
Effects on body
- CNS effects - euphoria, mood changes, mental clouding
- GI effects -constipation
- CV effects
- Sexual dysfunction