Examplify Flashcards

(36 cards)

1
Q

a patient presents with sigs of a chest infection and is coughing yellow sputum. You do not want to delay treatment. Which test will give you the best microbiological answer within the next 6 hours to help you choose the most appropriate Abx

A

gram stain sputum

doesn’t provide a specific organism but can make a good assumption

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2
Q

a 78yr old women presents to ~ED with a fever and acute confusion. Sepsis is suspected and the appropriate sepsis bundle initiated. With regards to sepsis this is….

A

identified doom observations and clinical features

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3
Q

between which vertebrae is a lumbar puncture performed?

A

L3/L4

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4
Q

which immune cells express the bacterial peptides pn MHC class II molecules

A

dendritic cells

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5
Q

what sort of bacteria does gentamicin work against?

A

gram negative

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6
Q

marker of muscle damage

A

creatine kinase

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7
Q

a 21 year old is admitted unconscious after attending a club. According to his friends he had taken ecstasy. The attached liver section shows features of

A

coagulative necrosis

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8
Q

carbon monoxide causes which type of hypoxia

A

histotoxic

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9
Q

what will occur to cells affected by the infarcation

A

influx of sodium and calicum

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10
Q

what will serum levels of calcium and phosphate be like in a pt with a calcified aortic valve

A

normal serum conc

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11
Q

heat shock proteins are present in

A

low concentrations in unstressed cells

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12
Q

the histology report describes the presence of Mallory’s hyaline within the hepatocytes. With which condition is this finding associated?

A

alcohol liver disease

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13
Q

what characteristic of clostridium allows it to survive outside of the host for long periods

A

spore formation

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14
Q

what type of bacteria is c.difficile

A

anaerobic bacteria

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15
Q

what antibiotic is prescribed for clostridium difficile infection

A

metronidazole

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16
Q

metronidazole is

A

active against anaerobic bacteria and also protozoan§

17
Q

what is the recommended treatment for MRSA infection

A

vancomycin given intravenously

18
Q

which cell is responsible for controlling HIV infection during the period where the pt remains clinically well

A

HIV specific CD8 T cell

19
Q

Acute HIV infection is characterised by the following

A

a flu like illness with mild rash

20
Q

how should you approach testing if a pt is HIV positive

A

use an opt-out approach following a discussion with the pt

21
Q

type of viral structure of HIV

A

single stranded RNA

22
Q

immunity against hep B is evidenced by the presence of adequate levels of

23
Q

why is staphylococcus epidermis good at adhering to the central line

A

it prodxcues a layer of slime that facilities adherence to prosthetic material such as central lines or intravenous catheters

24
Q

how and where is a murmur heard due to aortic stenosis

A

an ejection systolic murmur in the 2nd intercostal space on the right

25
how and where is tricuspid regurgitation (incompetence) heard
systolic murmur in the left lower sternal border
26
which mechanism of action of antibiotic is used to treat acute bacterial endocarditis
cell wall synthesis inhibitor
27
antibody produced after first exposure
IgM
28
antibody produced if virus has been previously encountered
IgG
29
where are prostaglandins produced and in response to what
in the cell membrane phospholipids in response to acute inflammation
30
which conditions are seen classically with alpha-1-antitrysin
emphysema and cirrhosis
31
what accumulates within a blister
serous exudate
32
in acute phase response of acute inflammation, which of the following proteins are produced by the liver in smaller amount than in the normal state
albumin
33
how does a neutrophil move from the blood to the infected tissue
chemotaxis, margination, diapedesis and phagocytosis
34
what occurs during acute inflammation
capillary hydrostatic pressure increases
35
which chemical mediator is available immediately at the site of injury
histamine
36
in which conditions is inflammation predominantly acute
lobar pneumonia not crohns, RA< sarcoidosis, TB (chronic)