Exercise 08: Coagulation Testing

Question 1

Complex process where blood started to form clots.

Answer 1

Coagulation / Clotting

Question 2

A test that measures blood’s ability to clot, and how long it takes to clot.

Answer 2

Coagulation Test

Question 3

Four (4) Factors that affect Coagulation / Clotting

Answer 3

1. Genes
2. Medications
3. Diseases
4. Current Medical Condition and Lifestyle

Question 4

Group of tests that evaluate the cells that circulate in blood, including RBCs, WBCs, and PLTs.

Answer 4

Complete Blood Count (CBC)

Question 5

The normal platelet count ranges from __________.

Answer 5

150,000 to 450,000

Question 6

It is the time required for the plasma to clot after an excess of thromboplastin and an optimal concentration of calcium have been added.

Answer 6

Prothrombin Time

Question 7

Normal Range of Prothrombin Time (PT)

Answer 7

10 to 15 seconds

Question 8

A PT test measures how long it takes for the clot to form in the blood sample. An INR is the type of calculation based on PT test results.

Answer 8

PT-INR Tests

Question 9

(T/F): INR levels that are too low, at risk for dangerous blood clots.

Answer 9

T

Question 10

(T/F): INR levels that are too high, are at risk for dangerous bleeding.

Answer 10

T

Question 11

If PT or INR is slightly elevated, withhold warfarin for __________, then reinstitute therapy with reduced dosage.

Answer 11

24 to 48 hours

Question 12

If PT or INR is elevated and bleeding occurs, administer __________ over 30 minutes. Patients who are bleeding may require the administration of blood products that contain clotting factors.

Answer 12

10 mg of Phytonadione

Question 13

It measures how long it takes your blood to form clot.

Answer 13

Activated Partial Thromboplastin Time (APTT) Test

Question 14

Normal Range of Activated Partial Thromboplastin Time (APTT) Test

Answer 14

21 to 35 seconds

Question 15

Three (3) Methods to Determine Blood Clotting Using Whole Blood

Answer 15

1. Slide Method / Milian’s Slide Method
2. Capillary Tube Method / Wright’s Method
3. Test Tube Method / Lee-White Method

Question 16

A method modified by Hinman and Sladen. The only apparatus required is the microscope slide.

Answer 16

Slide Method / Milian’s Slide Method

Question 17

Clotting Time Range of Slide Method / Milian’s Slide Method

Answer 17

4 to 10 minutes

Question 18

It could be by means of breaking the capillary tube or blowing the tubes.

Answer 18

Capillary Tube Method / Wright’s Method

Question 19

In which several glass tubes of narrow bore are filled with the same amounts of blood, and the time determined when the blood cannot be blown from the tube, or if blown out onto filter paper shows clot.

Answer 19

Wright’s Method

Question 20

A finger-stick blood sampler that is used to obtain blood for testing blood sugar (glucose).

Answer 20

Lancet

Question 21

It was used to monitor the heparin therapy, but now it is replaced by the APTT.

Answer 21

Test Tube Method / Lee-White Method

Question 22

Device that measure the clotting mechanisms of hemostasis.

Answer 22

Coagulation Analyzer

Question 23

It uses blood viscosity changes to determine clotting time.

Answer 23

Mechanical Impedance

Question 24

Monitor changes in the specimen’s optical density to detect the beginning of clot formation.

Answer 24

Photometric Principle

Question 25

When the clot forms, it entangles the magnet, breaking the electromagnetic coupling and allowing the magnet to rotate with the tube, terminating the test.

Answer 25

Electromagnetic Principle