Exercise and Hormones, Ergogenic aids, Recovery and Tapering Flashcards
(75 cards)
What are the roles of the Neuroendocrine system in exercise and recovery?
- Highly interactive and widespread roles
- Involved in breaking things down during exercise and building things up after
Why are endocrine effects of exercise considered complex?
Because many hormones have diverse and sometimes overlapping roles, impacting multiple tissues with both anabolic and catabolic effects.
How do peptide and steroid hormones differ in their action?
Peptides act fast by binding to surface receptors and using second messengers (e.g., cAMP), while steroids are slower, entering cells and acting at the nucleus.
What is the “big picture” role of hormones during and after exercise?
To maintain homeostasis in response to current and anticipated demands, including energy balance and recovery.
What happens hormonally during prolonged or competitive low-CHO exercise?
Catabolic hormones increase and insulin is suppressed.
What hormonal response is seen with high motor unit activation (intense exercise)?
More anabolic hormone profile during and after exercise.
What are steroid hormones made from, and when are they made?
- Made on demand from cholesterol
- They are lipid-soluble
- Travel with a transport protein and directly enter cell
What are peptide and amine hormones made from, and when are they made?
- Made in advance and stored
- They are water-soluble
- Travel freely and act on a target cell
What is a second messenger?
An intracellular molecule that amplifies a hormone’s effect after it binds to a receptor (e.g., cAMP).
What do hormones do?
They change rates of specific reactions in target cells by:
- Transport across membrane
- Secretory activity
- Enzyme activity
- Protein synthesis.
What determines a hormone’s activity in the body?
- Hormonal concentration in blood
- Secretion rate
- Rate of inactivation
- Quality of transport protein
- Plasma volume
- Receptor interaction
- Number of target cell receptors
- Affinity of binding
What is meant by hormone-receptor interaction?
It refers to the number and sensitivity of receptors, which can be up- or down-regulated.
What can acutely change hormone function during exercise?
- Secretion rate
- Plasma volume
- Metabolism/clearance
- Receptor sensitivity and density
- Antagonist hormone levels.
What is the HPA axis and what does it regulate?
Hypothalamus-Pituitary-Adrenal axis; it regulates catabolic stress responses like cortisol release.
What is the HPG axis and what does it regulate?
Hypothalamus-Pituitary-Gonadal axis; it regulates anabolic sex hormone responses.
Which hormones are primarily catabolic during exercise?
- Adrenaline
- Noradrenaline
- Cortisol
- Glucagon
Which hormones are primarily anabolic?
- Growth Hormone
- Testosterone
- Oestrogen
- Progesterone
- Insulin
What is the effect of training on catecholamine response?
Trained individuals have a lower response at the same absolute intensity, but not at the same relative intensity.
What does adrenaline do during exercise?
Increases glycogenolysis, cardiovascular output, and mobilisation of fats and immune responses.
How does exercise intensity affect glycogen use?
Higher intensity leads to more glycogen depletion.
What spares glycogen during moderate or prolonged exercise?
Mobilisation of free fatty acids (FFAs).
Why is FFA use reduced during heavy exercise?
Due to reduced blood flow to fat tissue and increased blood acidity.
What are the effects of glucagon (from pancreas) during prolonged or heavy exercise?
Increase glycogenolysis and gluconeogensis to maintain blood glucose
What are the effects of cortisol (from adrenal cortex) during prolonged or heavy exercise?
- Increase lipolysis
- Increase amino acids,
- Reduce glucose uptake to maintain blood glucose