export_upper respiratory viruses i Flashcards
Symptoms of the common cold
Rhinitis
Pharyngitis
Which symptoms are not found in the common cold?
No high fever, LRT involvement, or respiratory distress
When do colds occur most frequently?
Spring and fall
More common in children than adults
Complications of common cold
Otitis media
Sinus infections
Exacerbation of asthma
Which common cold virus exacerbates asthma the most?
Rhinovirus C
Which viruses cause the common cold (most to least frequent)?
Rhinovirus
Other known viruses
Coronavirus
Rhinovirus family and characteristics
Picornavirus
+ssRNA
Non-enveloped
Viral species of rhinovirus
A, B, and C
Over 100 different serotypes
Clinical implications of rhinovirus
Shed in respiratory secretions, transmission via direct contact with these secretions
Incubation period of rhinovirus
1-3 days
Treatment for rhinoviruses
Alleviation of symptoms
Antihistamines and decongestants
Antibiotics ONLY with bacterial superinfections
Prevention of rhinoviruses
Hand washing and cough/sneeze into elbow
Due to high number of serotypes, no vaccine is available
Non-SARS coronavirus characteristics
Enveloped
+ssRNA
Clinical implications of non-SARS coronaviruses
Replicate in epithelial cells
Transmission through large droplets
Optimal temperature is cooler than body temp
Incubation period for non-SARS coronaviruses
~3 days
Outbreaks of coronaviruses
Spring and winter months
Who is most likely to get a non-SARS cornavirus infection?
Infants and children
Non-SARS coronavirus treatment and prevention
Alleviate symptoms
No vaccine
Adenovirus characteristics
Non-enveloped
dsDNA
Adenovirus fiber proteins
Protrude from icosahedral capsid, used for attachment and are toxic
Clinical implications of adenoviruses
Transmission from oral, droplet inhalation, or conjunctiva
Replication in respiratory epithelia
May enter lymphoid tissue, and shedding can occur for up to 18 months
No seasonal pattern