extra Flashcards
(63 cards)
What is the mechanism of action of Aspirin?
Inhibits prostaglandin synthesis, hypothalamic heat regulator center, and platelet aggregation.
List common side effect of Aspirin.
- GI distress/bleeding
What are some adverse effects of Aspirin?
- Tinnitus/hearing loss
- Reye syndrome (in children)
*angioedema
*bronchospasm
What cautions or contraindications are associated with Aspirin?
- Peptic ulcers
- Bleeding disorders
- Asthma
*sick children
What patient teaching should be provided for Aspirin?
- Avoid alcohol
- Take with food
- Monitor for signs of bleeding
- Reye Syndrome
What is the mechanism of action of Ibuprofen?
Inhibits cox1 and cox2
List common side effect of Ibuprofen. What can help it?
- GI distress/ulcers (take with food)
What are some adverse effects of Ibuprofen?
- GI bleeding
- Tinnitus/hearing loss
What cautions or contraindications are associated with Ibuprofen?
- Avoid in renal disease
- Peptic ulcers
*bleeding disorder
What patient teaching should be provided for Ibuprofen?
Take with food, avoid concurrent NSAID use.
What is the mechanism of action of Celecoxib?
Selectively inhibits COX-2 to reduce inflammation without affecting platelet function.
List common side effects of Celecoxib.
- Headache
- Dizziness
- Sinusitis
- Dyspepsia
What are some adverse effects of Celecoxib?
- Hypertension
- GI bleeding
- Thromboembolism
What cautions or contraindications are associated with Celecoxib?
- Avoid in sulfa allergy
- Cardiovascular disease
What patient teaching should be provided for Celecoxib?
Take lowest dose for shortest time.
What are the adverse reactions of Infliximab?
- Fever
- Infections
- Hepatotoxicity
- Bone marrow suppression
What assessments or labs are required for Infliximab?
- CBC
- Liver function tests
- TB screening
What is Infliximab indicated for?
Used for autoimmune disorders such as rheumatoid arthritis and Crohn’s disease.
What are the adverse reactions of Febuxostat?
- Liver toxicity
- Rash
- Cardiovascular events
What assessments or labs are required for Febuxostat?
Monitor uric acid levels, liver enzymes.
What is Febuxostat indicated for?
Chronic management of gout by reducing uric acid production.
What is the mechanism of action of Carbidopa-Levodopa?
Carbidopa prevents breakdown of levodopa before it reaches the brain.
List side effects or adverse reactions of Carbidopa-Levodopa.
- Dyskinesias
- Orthostatic hypotension
- Urine discoloration
What patient teaching should be provided for Carbidopa-Levodopa?
Do not stop abruptly, take with low-protein food.