Extra (Final) Flashcards

(55 cards)

1
Q

Far more of the human brain is dedicated to [blank] than any other sense

A

Vision

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2
Q

What lies in front of photoreceptor cells at the back of the eye?

A

Neurons (transparent, do not hinder the very light sensitive photoreceptor cells) which are insensitive to light

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3
Q

How does the visual system solve the blind spot problem?

A

The optic disk (blind spot) is in a different spot in each eye
Left of fovea in left eye, right of fovea in right eye

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4
Q

Where are rods most abundant?
Where are cones most abundant?

A

Rods more abundant outside the fovea
Fovea has only cones

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5
Q

Difference of rods and cones with respect to light-absorbing pigments

A

All rods have same pigments (419 nm [white])
Cones have one of three pigments

S cone = 419 nm [blue, short]
M cone = 531 nm [green, medium]
L cone = 559 nm [red, long]

(Four pigments altogether form the basis of our vision)
(Frequencies shown are of max. absorption)

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6
Q

Constancy vs sensitivity of perceiving colour from blue, red, and green cones

A

Three cones are evenly distributed (perceive colour fairly constant across the visual field)

Numbers of red and green cones roughly equal, but there are fewer blue cones (not as sensitive to wavelengths in blue part of visual spectrum)

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7
Q

What are photoreceptors connected to?

A

Two layers of retinal neurons
First layer (amacrine, bipolar, horizontal cells)
Second layer (retinal ganglion cells)

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8
Q

Cortical columns

A

Strips of occipital lobe (0.5 mm)

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9
Q

What is the occipital lobe divided into?

A

6 visual regions (V1, V2, V3, V3A, V4, V5)
- V1 = primary visual cortex (striate cortex)
- Rest = extrastriate (secondary visual) cortex

Each extrastriate (secondary visual) cortex processes specific features of visual information
Each occipital region has different cytoarchitecture and unique inputs/outputs (different function)

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10
Q

Compression waves of changing air pressure (sound waves) move through what?

A

Compressible media, air, water, ground, etc. but not through vacuum of outer space

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11
Q

Sounds perceived as high pitched have ____?

A

More wave frequencies
(i.e., more waves per second)

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12
Q

In humans, the evolution of sound-processing systems for both language and music was accompanied by what?

A

Enhancement of specialized corticol regions (especially in temporal lobe)

Humans have marked expansion of auditory areas

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13
Q

Inner hair cells in the organ of corti synapse with what?

A

Neighbouring bipolar cells (axons that form the auditory nerve)

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14
Q

Free nerve endings for pain

A

(Nociception)
Slow

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15
Q

Free nerve endings for temp.

A

(Nociception)
Slow

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16
Q

Meissner’s corpuscle (touch)

A

(Hapsis)
Rapid

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17
Q

Pacinian corpuscle (flutter)

A

(Hapsis)
Rapid

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18
Q

Ruffini corpuscle (indentation)

A

(Hapsis)
Slow

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19
Q

Merkel receptor (steady skin indentation)

A

(Hapsis)
Slow

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20
Q

Hair receptors (flutter or steady skin indentation)

A

(Hapsis)
Slow

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21
Q

Muscle spindles (muscle stretch)

A

(Proprioception)
Rapid

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22
Q

Golgi tendon organs (tendon stretch)

A

(Proprioception)
Rapid

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23
Q

Join receptors (joint movement)

A

(Proprioception)
Rapid

24
Q

Auditory pathway from cochlea to primary auditory cortex

A

Cochlea
Superior olives (hindbrain)
Inferior colliculus (tectum, midbrain)
Medial geniculate nucleas (thalamus, diencephalon)
Primary auditory cortex

25
In the four homunculus model of the somatosensory homunculus, what do each of the four areas correspond to?
3a - muscles 3b - skin (slow) 1 - skin (fast) 2 - joints, pressure
26
What does area 2 of the four homunculus (somatosensory) model contain?
Multimodal neurons responsive to force, orientation, and direction of movement
27
What would unilateral damage to the spinal cord at the shoulder do?
Loss of fine-touch and pressure sensation on the same side of the body below the shoulder Loss of pain and temperature sensation on the opposite side of the body below the shoulder
28
For a corticospinal tract coming from the left hemisphere: The anterior corticospinal tract would control what? The lateral corticospinal tract would control what?
Trunk/muscles towards the midline on the left side Limbs/muscles away from the midline on the right side
29
What transmitter activates skeletal muscles? It also inhibits heartbeat
Acetylcholine
30
What determines if a transmitter will be excitatory or inhibitory?
The ion channel and its associated receptor
31
What chemical (transmitter) accelerates heart rate in animals?
Norepinephrine
32
What releases hormones into the bloodstream to excite or inhibit targets?
The pituitary gland (under control of the thalamus)
33
What process corresponds neurotransmitters being released into the synaptic cleft?
Exocytosis
34
Peptide transmitters
Synthesized in the cell according to DNA instruction Packaged in membranes in the Golgi body Transported on microtubules to axon terminal
35
How does an action potential play an important role in step 3 (neurotransmitter transport and release into cleft) of neurotransmission?
- Action potential arriving at the axon terminal opens Ca2+ channels - Ca2+ rushes in and forms a complex with synaptic vesicle
36
What are autoreceptors important for?
Negative feedback loop
37
Which glial cell is important to both uptake of neurotransmitters and the blood brain barrier?
Astrocyte
38
Gap junctions (electrical synapses) eliminate the 5 ms time delay in information, why are they not used more in the body?
Do not have plasticity (whereas chemical synapses do)
39
Can a neurotransmitter be excitatory at one location and inhibitory at another?
Yes
40
All motor neurons leaving the spinal cord use what neurotransmitter?
ACh
41
Small-molecule transmitters (amines)
Dopamine Norepinephrine (noradrenaline) Epinephrine (adrenaline) Seratonin
42
Small-molecule transmitters (amino acids)
Glutamate GABA Glycine Histamine
43
Small-molecule transmitters (purines)
Adenosine ATP
44
Which two enzymes help make ACh?
Acetyl CoA and ChAT acetyl coenzyme A choline acetyltransferase
45
What medication is administered to help Parkinson's disease?
L-dopa Helps make more dopamine
46
What two transmitters are the 'workhorses of the brain' because so many synapses use them?
Glutamate and GABA
47
Families of peptide neurotransmitters
Opioids Secretins Insulins Gastrins
48
Functions of neuropeptides
Hormones that respond to stress Enable a mother to bond Eating and drinking Pleasure and pain Contribute to learning
49
Predominant class of lipid transmitters
Endocannabinoids
50
Do cannabinoids dampen neural excitation or inhibition?
Both - since they inhibit the release of both GABA and glutamate
51
Examples of gaseous transmitters
CO NO H2S
52
At a skeletal muscle, cholinergic neurons are _____ ?
Excitatory (cause muscle contractions)
53
What is the single main receptor of the SNS system?
Nicotonic acetylcholine receptor
54
Least obstacles per route of drug administration
(Least obstacles) Injecting into brain Injected bloodstream Inhaled into lungs Injected into muscles (Most obstacles)
55
Two types of ganglion cells
P (parvo, midget) M (magno, parasol)