Extranuclear Inheritance (2) Flashcards
1
Q
3 mitochondrial DNA defects
A
MERRF
LHON
KSS
2
Q
MERFF
A
Myoclonic epilepsy and ragged red fiber disease
• maternal transmission
•symptoms:
Ataxia, deafness, dementia, seizures
3
Q
LHON
A
Lebers hereditary optic neuropathy
Maternal inheritance
Symptoms: sudden bilateral blindness by late 20’s
4
Q
KSS
A
Kearns-Sayre syndrome
Symptoms: blind, deaf, heart conditions
5
Q
Heteroplasmy
A
Variation of DNA within organelles such as mitochondria and chloroplasts within the same cell.
