f2f review

Question 1

First line of drug produce red-orange body fluids

Answer 1

Rifampin / Rifampicin

Question 2

Antimycobacterials that are hepatotoxic

Answer 2

All first-line drugs

Question 3

Antimycobacterial may cause peripheral neuritis

Answer 3

Isoniazid

Question 4

Drug to give if patient is experiencing a gout attack, hyperuricemia, and increased uric acid

Answer 4

Pyrazinamide

Question 5

2nd line drug that is given if TB strain is already resistant to Amikacin

Answer 5

Streptomycin

Question 6

Technical definition of your MDR TB

Answer 6

Resistant to both Isoniazid and Rifampin

Question 7

Duration of TB treatment intensive phase

Answer 7

2 months

Question 8

Duration of continuation/maintenance of TB treatment

Answer 8

4 or more months

Question 9

Duration of TB of the spine or TB meningitis treatment

Answer 9

1 year (2 months intensive, 10 months maintenance)

Question 10

Main drug used for leprosy

Answer 10

Dapsone

Question 11

Drug for multibacillary leprosy

Answer 11

Clofazimine

Question 12

Rifampicin analog that can be used or can be given orally but is not absorbed systemically

Answer 12

Rifaximin

Question 13

Rifampicin analog given to HIV/AIDS patients

Answer 13

Rifabutin

Question 14

May cause tendon rupture or tendonitis

Answer 14

Fluoroquinolones

Question 15

Causes myalgia-arthralgia

Answer 15

Streptogramins: Quinupristin-Dalfopristin

Question 16

Causes gray baby syndrome

Answer 16

Chloramphenicol

Question 17

Causes red man syndrome

Answer 17

Vancomycin

Question 18

Has the propensity to cause pseudomembranous colitis

Answer 18

Ampicillin
Co-Amoxiclav
Carbapenems/Meropenems
Clindamycin

Question 19

All drugs with MRSA activity

Answer 19

Vancomycin, Clindamycin
Streptogramins
Ceftaroline (5th gen beta-lactam)
Tigecycline, Eravacycline, Omadacycline
Rifampicin
Tedizolid
Cotrimoxazole
Levofloxacin, Gatifloxacin, Sparfloxacin

Question 20

Pseudomonal activity

Answer 20

Carbapenems (except ertapenem)
Cefoperazone
Ceftazidime

Question 21

What age can tetracyclines be given

Answer 21

8 and above

Question 22

Causes ototoxicity and nephrotoxicity

Answer 22

Aminoglycosides

Question 23

Most notable adverse effect of Tetracyclines

Answer 23

Tooth enamel discoloration
Enamel dysplasia

Question 24

Drugs that are contraindicated for pregnants

Answer 24

Tetracyclines:
Doxycycline
Demeclocycline
Minocycline
Tigecycline

Question 25

Prophylaxis for leptospirosis

Answer 25

Doxycycline

Question 26

Drugs that are allowed for Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Answer 26

Demeclocycline

Question 27

Used for increased gastric motility

Answer 27

Erythromycin

Question 28

Cause QT prolongation

Answer 28

Macrolides (Torsades de Pointes Arrhythmia)

Question 29

Used for malaria

Answer 29

Doxycycline Clindamycin Sulfadoxine + Pyrimethamine

Question 30

Used for chlamydia

Answer 30

Doxycycline 100mg 2x a day for 1 week

Question 31

Given to pregnant patient with chlamydia

Answer 31

Azithromycin

Question 32

Drugs that inhibit the growth of microorganisms

Answer 32

Bacteriostatic

Question 33

Drugs that kill the bacteria itself

Answer 33

Bactericidal

Question 34

In cell wall inhibitors, what chemical structure is responsible for determining drug susceptibility to enzymatic hydrolysis?

Answer 34

R group

Question 35

Used for gonorrhea

Answer 35

Ceftriaxone single IM dose

Question 36

Used for syphilis

Answer 36

Penicillin G single IM injection

Question 37

Which cephalosporin is active against MRSA

Answer 37

Ceftaroline (5th gen)

Question 38

Which cephalosporin is active against P. aeruginosa

Answer 38

Ceftazidime Cefoperazone

Question 39

Which cephalosporin is used as prophylaxis before surgery

Answer 39

Cefazolin

Question 40

Which carbapenem needs renal dehydropeptidase when administered

Answer 40

Imipenem

Question 41

Which among tetracyclines is derived from fluorocyclines

Answer 41

Eravacycline

Question 42

Which among tetracyclines is useful in the treatment for inappropriate secretion of ADH

Answer 42

Demeclocycline

Question 43

What is the ratio of Streptogramins

Answer 43

70% Dalfopristin (Strep A) 30% Quinupristin (Strep B)

Question 44

What is the target molecule of Streptogramins (MOA)

Answer 44

Inhibition of Protein synthesis by binding 50S Ribosomal RNA

Question 45

What is the target molecule of Linezolid

Answer 45

23S of the 50S RIbosomal Unit

Question 46

What part of the combination regimen in the treatment of H. pylori

Answer 46

Tetracycline

Question 47

What is the clinical application of streptomycin

Answer 47

Tuberculosis Plague Tularemia MDR strains of MTB

Question 48

What agent is reserved for serious infections resistant to aminoglycoside

Answer 48

Netilmicin

Question 49

Which is not recommended in the treatment of pharyngeal gonococcal infections

Answer 49

Spectinomycin

Question 50

What is the MOA of Trimethoprim

Answer 50

Inhibits dihydrofolate reductase

Question 51

What is the MOA of Sulfonamide

Answer 51

Inhibits dihydropteroate synthase

Question 52

Drug of choice for P. jirovecii infection

Answer 52

Co-Trimoxazole/Trimethoprim-Sulfamethoxazole

Question 53

Drug of choice for the prophylaxis in treatment anthrax

Answer 53

Fluoroquinolones: Ciprofloxacin

Question 54

3rd Gen Fluoroquinolones

Answer 54

Levofloxacin, Gatifloxacin, Sparfloxacin

Question 55

What is a respiratory fluoroquinolone used to treat pneumonia; second line TB

Answer 55

Levofloxacin (Single Dosing)

Question 56

Dose-dependent visual disturbances

Answer 56

Ethambutol

Question 57

What treatment is used for tuberculosis patients with HIV

Answer 57

Rifabutin

Question 58

What is the Drug of Choice for the treatment of Mycobacterium avium complex

Answer 58

Clarithromycin / Azithromycin

Question 59

What is the MOA of dapsone

Answer 59

Inhibition of Folic Acid

Question 60

Inhibits Mycolic Acid Synthesis

Answer 60

Isoniazid

Question 61

What inhibits your DNA-dependent-RNA polymerase

Answer 61

Rifampicin

Question 62

What vaccines are given at birth?

Answer 62

BCG Hepatitis B

Question 63

What Vaccines are Live-Attenuated

Answer 63

Measles, Mumps, Rubella Varicella Rotavirus (MMRV-BOY)

Question 64

When is 5 in 1 Vaccine given

Answer 64

6, 10, 14 weeks of age, 4, 6 years old, then every 10 years for Tetanus & Pertussis

Question 65

What vaccines can be given orally?

Answer 65

Oral polio: Salk: Live Vaccine

Question 66

Antigen that is able to induce an immune response

Answer 66

Immunogen

Question 67

Can elicit an immune response; Some are combined with antibodies

Answer 67

Vaccines

Question 68

They could develop faster immunity but could become a full-blown disease if you have a weak immune system

Answer 68

Live Vaccines