Bovine respiratory syncytial virus
Eosinophilic multinucleated giant cells associated with BRSV.
Condition is associated with pneumonia and emphysema
BRSV is associated with what clinical signs?
Outline the pathogenesis of PI-3.
Affects mucociliary escalator - ceases clearance
This respiratory pathogen is associated with:
- Alveolar hyperplasia
- Cellular inclusion bodies
What four pathogens are associated with the Bovine Respiratory disease complex?
What age group is usually affected?
- BHV-1 (IBR)
Calves < 6mo - cough, increased respiratory rate, nasal/occular discharge, pyrexia (39.5oC)
Ovine pulmonary adenomatosis - adenocarcinoma
OPA results in what pathogenic changes within the lung?
Type 2 pneumocyte adenocarcinoma - therefore increased release of surfactant into alveolar spaces.
- Overproduction of respiratory fluids
- Wt loss
Small ruminant lentivirus
Outline the pathogenesis of Maedi Visna
Transmitted by inhalation or through infected colostrum - the virus infects the respiratory parenchyma causing smooth muscle hyperplasia and lymphoid infiltration
Pneumonia and wasting - FATAL
What species are associated with Pasturellaceae? (x3)
- Mannheimia haemolytica
- Histophilus somni
- Pasturella multocida
- Mycoplasma ovipneumoniae
Bacterial fibrinous pleuricy and intra-alveolar fibrinous inflammation.
This commensal bacteria in the respiratory tract of ruminants causes pasturella associated disease.
What antibiotic therapies are used in treatment of Pasturellaceae associated disease
Atypical pneumonia in sheep
What clinical signs are associated with atypical pneumonia?
Non-progressive chronic pneumonia
Chronic soft cough
Decreased growth rate