Pneumovirus
Bovine respiratory syncytial virus
Eosinophilic multinucleated giant cells associated with BRSV.
Condition is associated with pneumonia and emphysema
Paramyxovirys
Para-influenza virus
BRSV is associated with what clinical signs?
Outline the pathogenesis of PI-3.
Affects mucociliary escalator - ceases clearance
Epithelial necrosis
SBI
This respiratory pathogen is associated with:
- Bronchitis
- Bronchiolitis
- Alveolar hyperplasia
- Cellular inclusion bodies
Parainfluenza 3
What four pathogens are associated with the Bovine Respiratory disease complex?
What age group is usually affected?
- BHV-1 (IBR)
- BRSV
- PI-3
- BVD
Calves < 6mo - cough, increased respiratory rate, nasal/occular discharge, pyrexia (39.5oC)
Jaagsiekte retrovirus
Ovine pulmonary adenomatosis - adenocarcinoma
OPA results in what pathogenic changes within the lung?
Type 2 pneumocyte adenocarcinoma - therefore increased release of surfactant into alveolar spaces.
Clinical signs:
- Dyspnoea
- Overproduction of respiratory fluids
- Wt loss
Small ruminant lentivirus
Maedi Visna
Outline the pathogenesis of Maedi Visna
Transmitted by inhalation or through infected colostrum - the virus infects the respiratory parenchyma causing smooth muscle hyperplasia and lymphoid infiltration
Pneumonia and wasting - FATAL
What species are associated with Pasturellaceae? (x3)
- Mannheimia haemolytica
- Histophilus somni
- Pasturella multocida
- Mycoplasma ovipneumoniae
Bacterial fibrinous pleuricy and intra-alveolar fibrinous inflammation.
Pasteruellaceae
This commensal bacteria in the respiratory tract of ruminants causes pasturella associated disease.
Histophilus somni
What antibiotic therapies are used in treatment of Pasturellaceae associated disease
Oxytetracycline
Florfenicol
Tylosin
Atypical pneumonia in sheep
Mycoplasma ovipneumoniae
What clinical signs are associated with atypical pneumonia?
Non-progressive chronic pneumonia
Chronic soft cough
Nasal discharge
Decreased growth rate
