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The Liver 2113 > Facts about the liver > Flashcards

Flashcards in Facts about the liver Deck (12):
1

Give 4 facts about the liver

1. The largest intestinal organ of the body
2. Huge reserve capacity
3. Regenerative
4. If critically damaged, multiple complications involve many body systems

2

What % of resting Cardiac output flows through the liver?

30%

3

What is the % of total blood volume held in the liver?

13%

4

What is the % of disease removal possible from the liver, but would still function relatively normal?

70-80%

5

To what % of its original size can a liver regenerate to?

5-10%

6

What is the functioning unit of the liver?

Hepatocyte

7

How are the hepatocytes arranged?

Hepatocytes are arranged in lobules

8

What is the service network in the liver?

The portal Triad: Hepatic artery (30%), Hepatic Portal Vein (70%) supply the blood and a bile duct forms a biliary drainage system.

9

What happens to the flow of blood in the liver?

From the Hepatic artery and the Hepatic portal vein, the blood flows into the SINUSOIDS, exposed to hepatocytes, then is drained by the hepatic veunles/veins, out of the liver.

10

What are the special cells in the liver that phagocytose bacteria and cell debris?

Kupffer cells

11

The liver is central to maintanence of homeostasis in the liver. What are all these functions?

Storage, Clearance, Filtration, Secretion, Excretion, Synthesis, Metabolism, Homeostasis

12

How does the liver fulfill its function of Detoxification?

It destroys endogenous and exogenous substances (i.e. substances formed inside and outside of the body)
It destroys cellular debris and invading bacteria via the kupffer cells
It causes the deamination of amino acids
Involves the removal of Bilirubin (yellow substance) in bile
Also is involved in hormone deactivation