Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

farma > farma coll 1 > Flashcards

farma coll 1 Flashcards

(65 cards)

Start Studying
1
Q

receptors in eyes

A

Alpha 1 - mydriasis
Alpha 2 - decr. IOP/F
Beta 1 - incr. secr. IOF
M3 - Myosis, incr. accomodation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Receptors in heart

A

Beta 1 - increase HR, conduction, contractility, automatism
Beta 2 - incr.
M2 - decrease HR, conductivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Receptors in BV

A

Alpha 1 - contraction
Beta 2 - relaxation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Receptors in Lungs

A

Beta 2 - decrease muscle tone
M3 - incr. Muscle tone, secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Receptors in GI

A

M3 - incr. muscle tone, motility, secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Receptors in Liver

A

Alpa 1 - incr.
Beta 2 - incr. glycogenolysis and glyconeogenesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

receptors in pancreas

A

Alpha 2 - decrease insulin
Beta 2 - increase insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

receptors in urinary bladder

A

Alpha 1 - sphincter (contraction)
Beta 2 - M. detrursor (relaxation)
M3 - m.Detrursor(contraction) + sphincter (relaxation)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

receptors in kidney

A

beta 1 - incr. renin release (incr. BP)
Beta 2 - incr. Renin release

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

receptors in glands

A

M3 - increase secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

receptors in uterus

A

Beta 2 - decrease muscle tone (relaxation)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

receptors in CNS

A

Alpha 2 - presynaptic pole (inhib)
Nn - autonomic ganglia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Receptors in Skeletal muscle

A

Beta 2 - increase muscle tone, glycogenolysis, K+ uptake
Nm - neuromuscular synapse (contraction)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Phenylephrine

A

-alpha 1 adrenoreceptor agonist
selective
-local vasocontriction
-nasal decongestants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Clonidine

A

-Alpha 2 adrenoreceptor agonist
selective
-hypotensive effect
-hypertesion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Isoprenaline

A

-β adrenoceptor
agonist
Non selective

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Salbutamol

A

-β2 adrenoreceptor
agonist
selective
-bronchodilation + tocolytic
- asthma + premature contractions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Epinephrine

A

-α,β adrenoceptor agonist
non selective

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Norepinephrine

A

-Nonselective α
selective β1 adrenoceptor agonist
- vasoconstriction
- acute hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Doxazosin

A

-α1 adrenoreceptor ANTAgonists
selective
- Vasodilation of peripheral blood vessels
(reflect tachycardia - dangerous)
decr. urethral tone + relaxes prostate
- hypertension + prostate adenoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Timolol

A

-Nonselective β adrenoblockers
-decr. IOF/P
-Glaucoma (used topically)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Propranolol

A

-Nonselective
β adrenoceptor ANTAgonist
-lipid soluble (BBB)
-hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Metoprolol
Bisoprolol

A

-Selective
β1 adrenoceptor
ANTAgonist
-hypertension, CAD, AFib, CHF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Carvedilol

A

-Selective α1,
nonselective β adrenoceptor ANTAgonist
-cardio depressant
-CHF, CAD, Hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Nebivelol
-selective beta1 ANTAgonist -vasodilation -hypertension
26
Pilocarpine
-M cholinoreceptor agonists -Eyes, reduce IOF/P -Glaucoma, Xerostomia
27
Neostigmine
-Anticholinesterase inhibitor - incr. Ach in body -> stimulation of N and M receptors -> muscle contraction -myasthenia gravis
28
Atropine
-M cholinoreceptor ANTAgonists Non-selective -incr. activity -bradycardia, preoperative, antidote to muscarine poisoning, eyes topical use mydriasis
29
Botulinum toxin (Sugammadex antidote)
-N ANTagonist -local Ach inhibition -> muscle relaxation -post-stroke spasticity etc. cosmetic surgery
30
Nicotine Suxamethonium
-N cholinoreceptor agonists - stimulation -> suppression - Intubation + short surgical manipulation
31
Rocuronium
-N cholinoreceptoru antagonists -Non depolarizing muscle relaxants -Muscle relaxation during surgical procedures
32
What is pharmacokinetics?
he branch of pharmacology concerned with the movement of drugs within the body
33
Terms for pharmacokinetics
Absorption -> Distribution -> Metabolism -> Elimination
34
What is pharmacodynamics?
the branch of pharmacology concerned with the effects of drugs and the mechanism of their action
34
Types of therapy?
EDPPRS Etiological-Diagnostic-Pathogenetic-Prophylaxis-Replacement-Syptomatic
35
What is Etiological therapy?
Treating the cause of the disease (eg. Bacterial infection)
36
What is therapy used for diagnostic purposes?
Use of drugs for diagnostic purposes eg. Contrast fluid
37
What is Pathogenetic therapy?
No known cause Known pathological process of disease (eg. hypertension, cancer)
38
What is Prophylaxis therapy?
Drugs used for prevention of the diasease (eg.Anticoagulants)
39
What is replacement therapy?
Substitution of something that is missing in the body (eg. Iron, vitamins)
40
what is symptomatic therapy?
Treating the symptoms of the disease (eg, allergic reaction)
41
What is medicinal toxicity?
produce harmful effects on the body or mind, often due to overdose, prolonged use, or adverse reactions
42
What is medicinal side effect?
unwanted, usually unpleasant, effects caused by medicines
43
List the types of Toxic syndromes
-sympathomimetic, anticholinergic, sedative-hypnotic (fast and furious) -opioid-induced(Depressed) -Combined
44
What is the "Fast and furious" Toxic syndrome?
1) Sympathomimetic toxidrome 2) Anticholinergic toxidrome Both with n increased heart rate and increased body temperature
45
What is Neuroleptic malignant syndrome?
caused by antipsychotic drugs -increased body temperature, - sweating, - muscle stiffness
46
What is Serotonin syndrome?
caused by psychotropic drugs (selective serotonin reuptake inhibitors and MDMA)
47
What is the "depressed" Toxic syndrome?
1) toxidrome caused by sedative-hypnotics; 2) opioid-induced toxidrome slower heart rate and decreased blood pressure
48
What is combined drug toxicity?
When a combined drug causes both anticholinergic/sympathomimetic toxidrome (Cetrizine+pseudepherine)
49
What are the types of Drug-induced liver injury? DILI
1)Predictable shortly after drug exposure 2)unpredictable common after use of a medication (paracetamol intoxication) 3)Acute laboratory tests have been changed for less than 3 months 4)Chronic laboratory tests have changed for more than 3 months
50
What are the types of clinical-biochemical types of liver damage?
1)Hepatocellular iver cell dmg + ALAT ASAT elevated + pain 2)Cholestatic itching + jaundice + incr. serum Alkaline phosphatase 3)Mixed various symptoms possible, nothing elevated predominantly
51
What are the risk factors for drug-induced nephrotoxicity?
▪ A decrease in "absolute" or "effective" intravascular circulating volume ▪ Age > 60 y. ▪ Diabetes mellitus ▪ Multiple nephrotoxin effect ▪ Heart failure ▪ Sepsis ▪ Chronic renal failure (GFR < 60 ml/min)
52
Definition of BAS
chemical compound that can modify the behaviour of cells and change the functions of organism
53
Definition of Pharmacological substance
BAS that has a definite pharmacological activity
54
Definition of Medicine
chemical used in the diagnosis, treatment or prevention of disease
55
Definition of Pharmaceutical form
Form of drug making for definite route of administration
56
What are the steps of development of new medicine?
1. Chemical preparing of the drug 2. Laboratory studies with animals 3. Clinical researches
57
What is a placebo?
Biologically inactive substance
58
What are the enteral routes of administration?
* per os * sublingually * transbuccally * rectally * duodenum by probe
59
What are the parenteral routes of administration?
* topical rout * transdermal rout * subcutaneously * intramuscularly * intravenously * intraarterially * subarachniodally * inhalation rout * intravaginally * insert into uterus or urine bladder
60
Subcutaneously
-slowly absorbed -Ony aqueous solutions
61
Intramuscularly
-quickly absorbed -Can be administered suspensions, oily solutions, irritating substances
62
Intravenously
-immediate effects -large volumes permitted -injected slowly -Only aqueous and soluble solutions
63
What is Toxicology of cholinesterase inhibitors?
acetylcholine excess in skeletal muscles Muscarinic manifestations: D diarrhea, defecation U urination M miosis B bronchoconstriction B bradycardia E excitation (of skeletal muscle and CNS) L lacrimation S salivation S sweating Central nervous system manifestations: agitation, seizures, coma
64
What is the Toxicology of atropine? Anticholinergic intoxication
Completely antagonize Ach in Muscarinic receptors Mad as a hatter Blind as a bat Red as a beet Hot as a hare Dry as a bone Full as a Flask Stuffed a a Pepper

farma (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions