Fat Soluble Vitamins Flashcards

1
Q

All vitamins can be synthesized in human body . True or false .

A
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2
Q

Biochemically , vitamins are inorganic heterogeneous compounds. True or false

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3
Q

List all the fat soluble vitamins.

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4
Q

List all the water soluble vitamins.

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5
Q

On the basis of function , water soluble vitamins can be further divided into :

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6
Q

Which vitamins are responsible for releasing energy?

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7
Q

Which vitamins are hematopoetic in function?

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8
Q

Vitamin c is a fat soluble vitamin. True or false.

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9
Q

Total number of vitamins required in human body are :

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10
Q

Match the following

1.Vitamin A. Tocopherol
2.Vitamin K. Cholecalciferol
3.Vitamin E. Phylloquinone
4.Vitamin D. Retinol

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11
Q

Both vitamin B7 and B9 are energy releasing in function. True or false.

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12
Q

Vitamin B4 & vitamin B8 are also essential vitamins for human body. True or false.

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13
Q

Collagen protein undergoes hydroxylation to increase its tensile strength. For this an important vitamin is required:

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14
Q

An anaemic patient can be given which vitamins as supplements :

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15
Q

Biochemically vitamin A is composed of ___________&__________

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16
Q

Role of vitamin A in our body .

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17
Q

Most biologically active form of vitamin A :

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18
Q

_____________ is the precursor of retinol.

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19
Q

Which chemical feature of vitamin A makes it an essential pigment for vision?

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20
Q

Side chain of vitamin A is composed of _______ double bonds and ______functional group.

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21
Q

Retinol on oxidation converts to ___________which on further oxidation converts to ___________ that functions as a hormone.

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22
Q

Vitamin A derivative that acts as hormone :

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23
Q

Retinol. —>. Retinal —> retenoic acid
<—-
A

Enzyme A is ?

A
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24
Q

Retinol is reversibly converted into 11- cis retinal which links via ______ amino acid to opsin protein forming _________, our visual pigment.

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25
Q

A patient with symptoms of night blindness visits a doctor and is given supplements of vitamin A bit even after few days of the treatment, there is no change in his situation. Which enzyme could be possibly defective?

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26
Q

Retinal is aldehyde form of retinol produced by oxidation at C-___

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27
Q

Conversion of 11-cis retinal to retinoic acid is an irreversible reaction. True or false.

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28
Q

An important vitamin that acts as hormone involved in regeneration:

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29
Q

Vitamin D is a derivative of which biomolecule ?

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30
Q

Activated form of vitamin D is

A
31
Q

Vitamin D regulates absorption of which ion from intestine and kidney?

A
32
Q

__________ is converted into cholecalciferol or vitamin D by the action of sunlight.

A
33
Q

The conversion of 7 dehydrocholestrol into cholecalciferol is an enzyme mediated step in skin . True or false.

A
34
Q

Which three organs are involved in vitamin D biosynthesis?

A
35
Q

Deficiency of vitamin D can cause hardening of blood vessels due to which there is deposition of fat and may result in heart attack and also reduced ability to fight infections.

True or false.

A
36
Q

Vitamin D derivative which acts as hormone.

A
37
Q

Total number of hydroxyl group present in 1,25 dehydrocholecalciferol :

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38
Q

Calcitriol is activated form of ______

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39
Q

Name the organ :

  1. 7 dehydrocholestrol is converted into cholecalciferol:
  2. Cholecalciferol is converted into 25 hydrocholecalciferol:
  3. 25 HCC is converted into 1,25 DHCC :
A
40
Q

Where does the first hydroxylation of cholecalciferol occurs and at which carbon position?

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41
Q

Calcitriol is produced in _______

A
42
Q

Cholecalciferol ——> HCC

This reaction is catalysed by which enzyme?

A
43
Q

All reaction in vitamin D biosynthesis are enzyme mediated. True or false

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44
Q

Second hydroxylation of 25 HCC occurs in ?

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45
Q

Which organs can be possibly failed if even after vitamin D supplements, the calcium absorption of a patient is not improved ?

A
46
Q

Receptors of vitamin D are found in
__________

A

Cytoplasm

47
Q

Vitamin D controls calcium metabolism by increasing which receptors on intestinal and kidney epithelial cells ?

A
48
Q

Vitamin D mediated calcium channels are generally expressed in _____ part of kidney.

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49
Q

TRPV 5 is found in __________ whereas TRPV 6 is found in ___________.

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50
Q

3 hormones involved in calcium metabolism.

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51
Q

TRPV stands for __________

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52
Q

Which calcium channels are expressed by action of vitamin D on the basolateral surface of intestinal epithelium?

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53
Q

Which calcium channels are expressed by action of vitamin D on the luminal side of intestinal epithelium?

A
54
Q

Translation of which proteins is triggered by vitamin D which help in storage of calcium within the cell and prevent their abnormal rise ?

A
55
Q

Vitamin D deficiency in children causes __________ while in adults causes __________

A
56
Q

Characteristics of rickets.

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57
Q

Tocopherol is another name for __________

A
58
Q

Tocopherols is a group of closely related _________(biomolecule)?

A
59
Q

Vitamin essential for normal reproductive function.

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60
Q

All tocopherols are composed of __________&___________.

A
61
Q

Unlike vitamin A, vitamin E does not contain conjugated hydrocarbon chain and hence cannot act as visual pigment. True or false.

A
62
Q

Vitamin ____ prevents non enzymatic oxidation in cell (between reduced biomolecules and oxidising cell environment) and thus act as potent antioxidant.

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63
Q

Vitamin K consists of _________&______

A
64
Q

Match the following

Vitamin K1 menadione
Vitamin K2. Phylloquinone
Vitamin K3. Menaquinone

A
65
Q

Vitamin K form produced by intestinal bacteria :

A
66
Q

Vitamin K form produced by plant ☘️

A
67
Q

Synthetic vitamin K is also known as _____________

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68
Q

Blood clotting factor protein undergo modification at ________ Amino acid residue to convert into functional form .

A
69
Q

Blood clotting factor protein undergo modification at glutamate residue to convert into functional form :

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70
Q

Blood clotting factor protein undergo modification at glutamate residue to convert into functional form gamma-carboxy glutamate.

The enzyme required for this is __________.

Which vitamin acts as coenzyme?

A
71
Q

_________ is a synthetic analog of vitamin c that inhibits vitamin K dependent carboxylation of blood clotting factors .

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72
Q

How does warfarin act as an anti coagulant ?

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73
Q

The only fat soluble vitamin that acts as a coenzyme?

A