Fat Soluble Vitamins Flashcards Preview

DEMS: Unit IIb > Fat Soluble Vitamins > Flashcards

Flashcards in Fat Soluble Vitamins Deck (17)
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1

Vit A: Biochemical fxns

  • Constituent of retinal visual pigments
  • Eyes, epithelium, infections
  • (FAM: Retin-A → retina → eye)

2

Vit D: Biochemical fxns

  • Hormone
    • (plasma membrane & nuclear receptor)
  • Bones
    • (FAM: Drink milk - good for bones)

3

Vit E: Biochemical fxns

  • Antioxidant
  • Neurologic
  • (FAM: E is for Erythrocytes)

4

Vit K: Biochemical fxns

  • Essential for carboxylation of factors II,VII, IX, X, C, S
  • (FAM: K for Koagulation)

5

Vit A: Physiologic Metabolic Role

  • Essential in the photochemical basis of vision
  • maintenance of conjunctival membranes and cornea
  • critical for epithelial cellular differentiation

6

Vit D: Physiologic Metabolic Role

  • Increases intestinal absorption of calcium and phosphate
  • increases bone resorption
  • helps immune system
  • Regulates cell growth & differentiation

7

Vit E: Physiologic Metabolic Role

  • Antioxidant, free radical scavenger
  • Cell membrane stabilizer

8

Vit K: Physiologic Metabolic Role

Coagulation

9

Vit A: Major dietary sources

  • Preformed Vit A: liver, dairy, egg yolks, fish oil
  • Precursor beta-carotene: abundant in deep yellow/orange and green vegetables

10

Vit D: Major dietary sources

  • UV light converts Vit D to active form 
  • fish liver oils, fatty fish
  • egg yolks
  • fortified milk and formulas

11

Vit E: Major dietary sources

  • Polyunsaturated vegetable oils
  • wheat germ

12

Vit K: Major dietary sources

  • Leafy vegetables
  • fruits
  • seeds
  • synthesized by intestinal bacteria

13

Vit A: Characteristic deficiency findings

  • Night blindness, Xeropthalmia → extreme dryness of cornea, immune dysregulation.
  • Used to treat measles
  • Can be due to low fat intake or fat malabsorption

14

Vit D: Characteristic deficiency findings

  • @ children: Rickets
    • failure of maturation of cartilage & calcification on bones)
  • @ adults: osteopenia/malacia, osteoporosis
  • macrophages that can’t kill pathogens
  • Due to: low sun exposure, dietary intake, fat malabsorption, obesity, liver/renal dz

15

Vit E: Characteristic deficiency findings

  • Irreversible neurologic degeneration (DTR go 1st)
  • caues: Fat malabsorption syndromes, hemolytic anemia, premature infants

16

Vit K: Characteristic deficiency findings

  • Prolonged coag time
  • hemorrhagic disease of newborn
  • rash/skin findings
  • causes: Chronic antibiotics, poor diet

17

Circumstaces with increased risk of vitamin deficiency or toxicity

  • Inadequate food intake/variety
  • Fat malabsorbtion
  • Pancreatic insufficiency
  • Liver disease → low bile salts
  • Protein energy malnutrition
  • Increased nutrient requirements/metabolic demands
  • Maldigestion
  • Drug-nutrient interactions