Feline Panleukopenia Virus

Question 1

is a highly contagious, often fatal, viral disease of cats that is seen worldwide

Answer 1

Feline panleukopenia

Question 2

are affected most severely of feline panleukopenia

Answer 2

kittens

Question 3

The causative parvovirus is very resistant; it can persist for ______ at room temperature in the environment if protected in organic material.

Answer 3

1 year

Question 4

FPV; synonymous with feline panleukopenia virus

Answer 4

Feline Parvovirus

Question 5

Feline parvovirus is closely related to mink enteritis virus and the type 2 canine parvoviruses (CPV) that cause ___________

Answer 5

canine parvoviral enteritis

Question 6

FPV can cause disease in all ______ and in some members of related families, but it does not harm canids

Answer 6

felids (racoon and mink)

Question 7

Conversely, some currently circulating CPV strains ______, _____, _____have been shown to cause feline panleukopenia in domestic cats and larger felids.

Answer 7

CPV-2a, -2b, and -2c

Question 8

FPV dominates over CPV as the cause of ________ worldwide

Answer 8

feline panleukopenia

Question 9

Vaccines that contain ____ protect cats against disease caused by CPV, although vaccines that contain FPV induce much lower antibody titers against CPV-2c than against FPV.

Answer 9

FPV

Question 10

Virus particles are abundant in all secretions and excretions during the acute phase of illness and can be shed in the_____ of survivors for as long as______ after recovery.

Answer 10

feces
6 weeks

Question 11

parvoviruses can be transported long distances via fomites

Answer 11

shoes and clothing

Question 12

FPV can be destroyed by exposure to a _____________

Answer 12

1:32 dilution of household bleach
(6% aqueous sodium hypochlorite)

Question 13

are also highly effective. It is important that contaminated surfaces are thoroughly cleaned of organic material before disinfectants are applied.

Answer 13

Peroxygen disinfectants (eg, potassium peroxymonosulfate)

Question 14

Cats are infected _______ by exposure to infected animals, their feces, secretions, or contaminated fomites.

Answer 14

oronasally

Question 15

FPV infects and destroys actively dividing cells in ________, _________, ________ and—in very young animals—_________, and ____________

Answer 15

bone marrow, lymphoid tissues, intestinal epithelium
cerebellum and retina.

Question 16

In pregnant queens, the virus may spread _________ to cause _________, __________, _________ or _________

Answer 16

transplacentally

embryonic resorption, fetal mummification, abortion, or stillbirth.

Question 17

FPV infection of kittens in the perinatal period may destroy the _______________, leading to __________, _________ and ___________

Answer 17

germinal epithelium of the cerebellum

cerebellar hypoplasia, incoordination, and tremor

Question 18

FPV Physical examination typically reveals profound _______, _________ and _______

Answer 18

depression, dehydration, and sometimes abdominal pain.

Question 19

FPV Acute cases show __________, and __________ after an incubation period of 2–7 days

Answer 19

fever (104°–107°F [40°–41.7°C]) depression, and anorexia

Question 20

can induce immediate vomiting—may reveal thickened intestinal loops and enlarged mesenteric lymph nodes.

Answer 20

Abdominal palpation

Question 21

In cases of _________, ataxia and tremors with normal mentation are seen.

Answer 21

cerebellar hypoplasia

Question 22

________, if present, appear as discrete gray foci.

Answer 22

Retinal lesions

Question 23

FPV mortality is highest in kittens___________

Answer 23

<5 months old.