Female Embryogenesis

Question 1

What happens in absence of SRY protein?

Answer 1

sex cords fragment into clusters of epithelial cells that each surround a PCG

-each cluster forms a primordial follicle along the cortex of the ovary

Question 2

Developmental sequence of embyronic ovaries

Answer 2

1. Both paramesonephric and mesonephric ducts are intact, coelomic epithelium of primitive gonads will develop into ovarian cortex
2. Rete tubules and sex cords regress and paramesonephric duct enlarges
3. Primitive follicles begin developing in cortex, mesonephric tubules and ducts keep regressing
4. Clusters of follicles develop at periphery of ovary, sex cords are gone and gonad resembles an ovary (has cortex and medulla), mesonephric ducts and tubules are gone

Question 3

Developmental sequence of female repro tract

Answer 3

1. Fusion of caudal part of paramesonephric ducts to one other and to budding UG sinus
2. Further fusion of ducts to form cranial portion of uterus and cervix, bud of UG sinus elongates to develop vaginal canal further
3. Vulva & vestibule are formed by ectoderm that invaginates in mesoderm-derived repro tract

Question 4

Is the female repro tract retroperitoneal?

Answer 4

Yes, it is supported by the broad ligament, a layer of dorsal peritoneum (mesentry)

Question 5

Paramesonephric ducts and gonadal regions

Answer 5

Cranial regions stay seperate from one another and will develop into uterine horns and oviducts, ducts get closer to one another as they move caudally