Female Repro Microstructure

Question 1

Eggs per Month

Answer 1

20-50 recruited/ month to develop. Secondary follicles dependent upon FSH for development

Question 2

Ovary Blood Supply

Answer 2

Mesovarium blood vessels in mid medulla

Question 3

tunica albuginea

Answer 3

surrounds the ovary

Question 4

Follicle development at late primary follicle

Answer 4

follicular cells&raquo_space; granulosa cells

ooocyte forms, surrounded by z pellucida, theca interna

Question 5

Secondary/Antral Follicle

Answer 5

theca externa/interna, antrum forming, granulosa cells

Question 6

Mature/Graafian Follicle

Answer 6

Theca externa/interna, ring of granulosa cells surround liquor follicle, corona radiata, cumulus oophorus

Question 7

Appearance of Primary Oocyte

Answer 7

larger, cuboidal granulosa cell

Question 8

Components of Zona Pellucida

Answer 8

glycoprotein and acid proteoglycans

ZP1, 2, 3

Question 9

What’s in an antrum

Answer 9

liquor follicule (FSH, Estrogen)

Question 10

Secondary Follicle components

Answer 10

theca externa: fibroud

granulosa interrupted by antrum

Question 11

Purpose of antrum

Answer 11

steroids, pituitary hormones, local growth factors

Question 12

Appearance of graafian

Answer 12

antrum enlarges and the oocyte is displaced

granulosa cells surround oocyte

Question 13

What surrounds Oocyte in Graafian

Answer 13

Corona radiata Cumulus Ooopohorus

Question 14

Early Stage of oocyte from follicle: antrum

Answer 14

mucoplysacchrides depolymerize and increase colloid osmotic pressure.

granulosa less cohesive and cumulus loosens

Question 15

Where does follicle break down

Answer 15

stigma

Question 16

Role of LH pre ovulation

Answer 16

stimulate granulosa to produce plasminogen activator and cause plasmin.

follicle wall ruptures

Question 17

Role of LH post ovulation

Answer 17

cause granulosa cells to transform into gran lutein and theca intern into theca lutein

Corpus Lutein!

Question 18

Corpus Luteum

Answer 18

secrete progesterone and estrogen.

Enlarges if implantation occurs,

Question 19

Granulosa Lutein

Answer 19

Progesterone produceers

Question 20

Theca Lutein

Answer 20

Estrogen precursors

Question 21

Follicle Atresia

Answer 21

dying follicle

Question 22

Role of Estrogen

Answer 22

• promote development and maintenance of reproductive structures
• increase protein metabolism
• lower cholesterol
• inhibit GnRH, FSH, LH

Question 23

Role of Progesterone

Answer 23

• prep endometrium for implantation
• prep breasts to secrete milk
• inhibit GnRH and LH

Question 24

Oviduct Functions

Answer 24

• transport germ cells
• capacitation and fertilization
• transport zygote

Question 25

Ampulla anatomy

Answer 25

- many mucosal folds into lumen | - mucus membrane with epithelium and lamina propria

Question 26

Oviduct Cell types

Answer 26

1) ciliated: aid transport of sperm up isthmus 2) non-ciliates secretory cells 3) SM muscle coat for peristalsis

Question 27

Epithelium of Endometrium

Answer 27

pseudostratified ciliates and some w/ microvilli

Question 28

Layers of Endometrium

Answer 28

Stratum Functionalis (shed) Stratum Basalis Myometrium

Question 29

Cycles of Menstral Period

Answer 29

Proliferative-endo regenerates Secretory- endo thickens Ischemic- drop in hormones Menstrual- functional layer GONE

Question 30

Arterial Supply to Endometrium

Answer 30

Uterine artery in myometirum | upward branches spiral and form capillary beds at functional is surface

Question 31

When is the Late Secretory Phase

Answer 31

Days 15-28

Question 32

Endocervix cell type

Answer 32

simple columnar mucus-secreting cells

Question 33

Phases of mucus secretion

Answer 33

Around ovulation: thin and watery (estrogen) | After ovulation: viscous (progesterone)

Question 34

95% cervical cancers occur where

Answer 34

in squamo-columanr junction zone of cervix (low pH and squamous metaplasia healing leaves it susceptible to virus)

Question 35

Vagina cells

Answer 35

- stratified squamous epithelium - NO GLANDS - fibroelastic lamina propria - layer of circular SM - skeletal muscle at orifice

Question 36

Vaginal Exctretion?

Answer 36

synthesizes glycogen in response to estrogen (lactic acid after bacteria..)

Question 37

Breast Tissue change at pregnancy

Answer 37

inactive ducts proliferate into alveoli at ends of ducts, fully differentiate and secrete milk

Question 38

Hormones of breast change

Answer 38

estrogen, progesterone, lactogenic hormones

Question 39

Breast Protein release

Answer 39

via exocytosis of merocrine secretion. lipids discharged via apocrine