Female Reproduction, Breast, Ova, Tumescence, Climax and Fertilization Flashcards Preview

Endo/Repro Exam 1 > Female Reproduction, Breast, Ova, Tumescence, Climax and Fertilization > Flashcards

Flashcards in Female Reproduction, Breast, Ova, Tumescence, Climax and Fertilization Deck (27):
1

What layer of cells surround the primordial follicle?

One layer of squamous epithelial cells

2

What occurs to the single layer of squamous cells once the primordial follicle is stimulated to become the primary follicle?

They become cuboidal granulosa cells

3

What denotes a secondary follicle?

When several pockets of antral fluid begin to develop

4

What denotes a tertiary follicle?

When the several pockets of antral fluid coalesce into a single chamber of fluid

5

What stimulates a tertiary follicle to become a preovulatory mature stage (Graafian)

LH

6

What occurs once the Graafian follicle erupts in ovulation?

The follicle becomes a corpus luteum and later a corpus albicans

7

What stage is the ovum arrested in?

Prophase I (of meiosis I)

8

What keeps the ovum in meiosis I?

OMI ovum maturation inhibiting factor

9

What does side chain cleavage enzyme cut?

The bond between cholesterol's C-20 and C-22 leaving a 21 carbon progesterone compound

10

Five classes of steroids?

Progesterones (progestins)
Androgens
Mineralocorticoids
Glucocorticoids
Estrogens

11

What enzyme cleaves C-20 and C-21 to make 19-C androgens?

3beta-Hydroxysteroid Dehydrogenase

12

What enzyme cuts off C-19 to make 18-C estrogens?

Aromatase

13

Follicular phase major product of follicle?

Estradiol

14

Luteal phase major products of corpus luteum?

Progestins

15

What can't theca cells produce?

Estradiol due to lack of aromatase

16

What can't granulosa cells produce?

Androstenedione due to lack of 17a-hydroxyprogesterone

17

Steps of testosterone formation in theca cells?

Cholesterol
Pregnenolone
Progesterone
17a-OH progesterone
Androstenedione
Testosterone

18

Steps estradiol formation in granulosa cells?

Cholesterol
Pregnenolone
Progesterone
Androstenedione
Testosterone and Estrone
Estradiol

19

What stimulates aromatase activity in the granulosa cells?

FSH

20

Two cell theory summary:

The preovulatory follicle produces estradiol through a paracrine interaction between theca and granulosa cells. The theca cells provide the substrate, androstenedione, to the granulosa cell for estradiol production. The granulosa cells express the enzymes necessary for transformation of androstenedione to estradiol

21

What does the glandular tissue of the breast consist of?

Branching ducts and terminal secretory lobules that converge into larger lactiferous ducts at the opening of the nipple

22

What structure in the uterus is used for implantation of the egg?

Pinopodes

23

What cell type is the vagina?

Stratified squamous epithelium

24

Outer layer of the ovum?

Zona pellucida

25

What cells surround the zona pellucida?

Corona radiata

26

What is the perivitelline space?

Space between the zona pellucida and the oocyte cell membrane

27

What causes a vagina to secrete mucus?

PSNS impulses to vaginal epithelium and bulbourethral glands to secrete mucus